Proteins are constructed from a limited alphabet of ~20 amino acids, yet the origins and selection of this specific alphabet are unresolved.
genomics
Membrane Information Organization At The Origin Of Life: From Interfaces To Informational Bodies
Membranes are usually treated as passive containers in origin-of-life models, confining prebiotic chemistry, buffering diffusion, and sustaining gradients.
Physiological Trade-offs Drive The archaeal Dominance And Carbon Turnover In Deep Subsurface
Marine sediments host a vast deep biosphere, yet how microorganisms persist under severe energy limitation and govern long-term organic carbon (OC) preservation remains poorly understood.
Liquid–liquid Phase Separation As A Driver Of Abiogenesis And Evolution
The origin of life may have emerged through physical mechanisms that enable molecular organization and self-assembly. Building on Alexander Oparin’s concept of coacervate droplets, liquid–liquid phase separation (LLPS) offers a […]
Radiation-Resistant Microbes: Pioneers for Life Beyond Earth
Radiation is one of the most pervasive environmental stressors that has profoundly influenced microbial evolution, driving the development of intricate survival strategies in extreme environments.
Artificial Intelligence Aided Design Of Peptides With Custom Secondary Structure Motifs And Reduced Amino Acid Alphabets
Proteins are highly diverse functional polymers where the specific sequence of amino acids, selected from a standard genetically-encoded alphabet of twenty (C20), determines the structure and ultimately the function of […]
What It Takes To Solve The Origins Of Life: An Integrated Review. Part 1 Experimental Methods And Data Repositories
The origin(s) of life (OoL), which has puzzled scientists for centuries, remains a major scientific challenge in the 21st century.
What It Takes To Solve The Origins Of Life: An Integrated Review. Part 2: Theoretical Methods And Emerging Trends
The origin(s) of life (OoL), which has puzzled scientists for centuries, remains a major scientific challenge in the 21st century. Understanding the processes relevant to the OoL demands theoretical frameworks […]
Hidden Viruses Reshape One Of Earth’s Largest Carbon Systems
Viruses play a far more active role in Earth’s carbon cycle than previously understood, according to new research that reveals how they infect and control microbes responsible for carbon production […]
Biosignatures: Evidence for Endogenous Collagen in Edmontosaurus Fossil BoneAnalytical Chemistry via PubMed
Reports of proteins in fossilized bones have been a subject of controversy in the scientific literature because it is assumed that fossilization results in the destruction of all organic components.
