![A symbiotic scenario for co-evolution of the ribosome and the replicase. Two variations of the scenario are depicted, whereby the peptidyltransferase center (PTC) and the replicase (REP) ribozymes are encoded by distinct (A) or the same (B) RNA molecule. The figure depicts three major stages of cellular evolution from the primordial RNA world (left) to the intermediate RNA-protein world (center) and the last universal cellular ancestor (LUCA, right). The major events occurring during each stage are briefly described in the corresponding information boxes at the bottom of the figure. -- [q-bio.PE]](https://i0.wp.com/astrobiology.com/wp-content/uploads/2026/08/The-selfish.png?resize=1200%2C712&ssl=1)
[q-bio.PE]. The ribosome is responsible for protein synthesis in all cells, and is the largest energy consumer in the cell.
Origin & Evolution of Life
Posted inPanspermia
Natural Lithopanspermia to Earth: Transport, Shielding, and Survival Limits for Solar-System and Extrasolar Donor Classes
[physics.gen-ph] Natural panspermia is a transport-and-establishment hypothesis, not a theory of abiogenesis. The Earth-specific question is whether any nonterrestrial donor remains competitive with terrestrial origin once launch, planetary-system escape, transit, […]
Posted inOrigin & Evolution of Life
Crossing The Functional Desert: Cascade-Driven Assembly And Feasibility Transitions In Early Life
[physics.soc-ph] The origin of life poses a problem of combinatorial feasibility: How can temporally supported functional organization arise in exponentially branching assembly spaces when unguided exploration behaves as a memoryless […]
![Graphical abstract -- [The Journal of Membrane Biology]](https://i0.wp.com/astrobiology.com/wp-content/uploads/2026/08/From-Meteorites.png?resize=1200%2C712&ssl=1)
Posted inBiochemistry & Organic Chemistry
From Meteorites to Membrane Rafts: Ganglioside-Incorporating Prebiotic Vesicles and the Emergence of Membrane Domain Organization
[The Journal of Membrane Biology] Life requires membranes. But what were the first membranes made of, and how did they acquire the functional complexity of modern cells?
![The origin of life is the first, arguably, the most important and also the most enigmatic major transition in evolution (MTE). [q-bio.PE]](https://i0.wp.com/astrobiology.com/wp-content/uploads/2026/08/The-first.png?resize=1200%2C718&ssl=1)
Posted inOrigin & Evolution of Life
The First Major Transition: Origin Of Life From A Multilevel Selection Perspective
[q-bio.PE] As all MTE, the transition at the origin of life can be constructively addressed only within the conceptual framework of multilevel selection. The two levels of selection relevant for […]
Posted inOrigin & Evolution of Life
RNA Droplets May Have Helped Start life on Earth
[University at Buffalo] It’s one of the origins of life’s chicken-or-the-egg problems: How could RNA have helped give rise to the first cells before there were cells to contain them?
Posted inOrigin & Evolution of Life
Metagenomics Deciphers Diagenetic Processes Of Ferruginous Mineralization In The Deep Biosphere
[Nature Communications Earth & Environment] Ferruginous conditions in the Precambrian oceans gave rise to ancient iron formations that contain the oldest recognized traces of life in the form of mineral […]
![Photographs of the mineral and inorganic substrates used in this study and the corresponding hybrid materials obtained. -- [Nature]](https://i0.wp.com/astrobiology.com/wp-content/uploads/2026/08/Synthesis.png?resize=1200%2C720&ssl=1)
Posted inOrigin & Evolution of Life
Synthesis Of Mineral-organic Hybrid Materials Under Dynamic Prebiotic Conditions
[Nature] The increasing of molecular complexity must be understood as a planetary phenomenon where prebiotic chemistry and geological settings converge. In this scene, HCN chemistry may have played a crucial […]
![Selection on a collective trait drives the origin of heredity. (A) Intracellular 5 competition drives the dominance of the red plasmid when fluorescence is enforced (left-hand panel) while poor inheritance and carriage costs purge the ancestral plasmid population entirely when no selective gate is used (right-hand panel). Coloured zones show the proportion of the population in each colour class through 21 cycles: red only, green only, yellow (red plus green), white (cells without fluorescence). -- [biorxiv.org]](https://i0.wp.com/astrobiology.com/wp-content/uploads/2026/08/Forging.png?resize=1200%2C718&ssl=1)
Posted inGenomics, Proteomics, Bioinformatics
Forging An Evolutionary Individual From Separate Replicators
[biorxiv.org] A central puzzle in the evolution of individuality is the origin of heredity. Egalitarian transitions integrate formerly independent replicators into a higher-level individual, but this requires the collective to […]
Posted inOrigin & Evolution of Life
Concurrent Phosphite Oxidation And Adenosine Phosphorylation Under Prebiotic Evaporative Conditions
[Journal of Molecular Evolution] Here, we investigate the concurrent oxidation of phosphite and phosphorylation/phosphonylation of adenosine under prebiotically plausible conditions.