[q-bio.GN] Reference genome assemblies are foundational resources across the biological sciences as they begin to expose the fundamental building blocks of each species and the molecular toolkits vital for adaptation […]
Genomics, Proteomics, Bioinformatics
Posted inGenomics, Proteomics, Bioinformatics
Chemical Structure Of RNA With Thiophosphate-modified Linker
[Tokyo Metropolitan University] Original source (Japanese) https://kyodonewsprwire.jp/release/202609246495 Points We discovered that the linkers (connection points) between ribosomal RNA (rRNA) and transfer RNA (tRNA) in archaea, microorganisms that inhabit high-temperature environments, […]
Posted inGenomics, Proteomics, Bioinformatics
Pathways Of Early Evolution From The Perspectives Of A Riboreplisome — The Ultimate RNA Machine Of Life
[q-bio.PE] Translation of the genetic code into proteins is universal across life, with ribosomes serving as the ancient molecular machines enabling this information transformation. We propose that early replication and […]
Posted inMicrobiology & Virology
Bacteriophage Qβ: Six Decades at the Frontier of Molecular and Viral Evolution Genome, Particle And Mutational Landscape Of Bacteriophage Qβ
[q-bio.PE] Bacteriophage Qβ, first isolated in 1961, has served for more than six decades as a model system for molecular and viral evolution.
Posted inMicrobiology & Virology
Controlled Near-space Exposure Induces Community Restructuring In An Ocean Water Microbiome
[biorxiv.org] Marine microbiomes may experience extreme environmental stress during atmospheric transport, yet how near-space conditions reshape natural microbial communities remains poorly understood.
Posted inGenomics, Proteomics, Bioinformatics
Catalog Of Mitochondria Across Life’s Family Tree Unearths New Roles For The Cell’s Powerhouse
[Broad Institute of MIT and Harvard] A research consortium has generated the broadest look yet at the proteins that make up mitochondria, capturing the organelle’s diversity across multiple branches on […]
Posted inCryobiology
Characterization Of Cold-adapted, Halotolerant Glycoside Hydrolase From Antarctic Halomonas sp. KS41843
[Applied Microbiology and Biotechnology ] Cold-adapted and halotolerant enzymes are promising candidates for industrial biocatalysis because they remain active under low-temperature and high-salinity conditions.
Posted inGenomics, Proteomics, Bioinformatics
Ancient Genome Function Persists Despite Frequent Mutations
[Heinrich-Heine University Duesseldorf] Centromeres are crucial for cell division and emerged early in evolution. A research team led by Heinrich Heine University (HHU) Düsseldorf and the Max Planck Institute for […]
Posted inAstrochemistry
Nonequilibrium Formation of C4 Carbonyls in Interstellar Ices Linked to Amino Acids
[ACS Central Science] Complex organic molecules in interstellar ices and carbonaceous asteroids record key steps in the chemical evolution toward life, yet the origin of branched carbonyl compounds a fundamental […]
Posted inBiochemistry & Organic Chemistry
Uncatalyzed Guanosine Phosphorylation under Potentially Prebiotic Conditions
[Chem EurJ] The phosphorylation of nucleosides and their subsequent polymerization are key issues in the study of the Origins of Life. How these chemical processes took place on primitive Earth […]