Editor’s note: As we expand outward from Earth to other worlds we are almost certainly going to encounter things we did not expect to find – things that are unlikely […]
genomics
The RNA-First Fallacy: Conflating Evolutionary Ancestry with Prebiotic Primacy
The RNA-World hypothesis remains the most widely accepted framework in origins-of-life research, anchored in compelling biochemical evidence for RNA’s deep evolutionary ancestry. However, this viewpoint routinely extends beyond that and […]
A Lack Of Sex Held Back Life’s Diversity For Millions Of Years
The way that Earth’s first animals reproduced held back life’s diversity for millions of years, until stress and competition led to the development of sexual reproduction, which in turn accelerated […]
Rethinking the Last Universal Common Ancestor of Life: Network Convergence and the Root of the Tree
The tree of life is rooted at the “origin of life.” One model holds that core biochemistry, which includes the genetic code, the ribosome, biopolymer backbones, and amino acid and […]
Assessing the Earliest Evidence for Life in the Geologic and Genomic Records
Both the geologic and genomic records provide information on the earliest history of terrestrial life.
Tardigrades As An Emerging Model Animal For Astrobiology Research: A Case Study
Tardigrades are extraordinarily resilient creatures, capable of withstanding radiation, extreme dehydration, temperature fluctuations, and even the vacuum of space, which makes them exemplary models for studying the viability of life […]
Stereoselective Phosphorylation of d-Ribose as a Driver of Life’s Homochirality
Life demonstrates remarkable homochirality of its major building blocks: nucleic acids, amino acids, sugars, and phospholipids. Phospholipid bilayer vesicles (liposomes) are formed at the water/air interface from Langmuir layers and […]
A Glimpse At The Origins Of Life Through A Deceptive Mirror
Imagine looking at yourself in the mirror, only to find that your reflection is governed by different laws than you are: Identical movements produce different outcomes, and what seems like […]
Synthetic Biology As An Empirical Tool For Evolutionary Theory
Evolutionary biology has traditionally inferred process from patterns in extant organisms and the fossil record, leaving many foundational questions constrained by their historical nature.
Scientists Reveal Disease Genes From Reconstruction Of Ancestor To All Complex Life
A University of Texas at Austin-led team has reconstructed the most detailed map to date of the molecular machines that carried out the functions of life in an ancient ancestor […]
