![Selection on a collective trait drives the origin of heredity. (A) Intracellular 5 competition drives the dominance of the red plasmid when fluorescence is enforced (left-hand panel) while poor inheritance and carriage costs purge the ancestral plasmid population entirely when no selective gate is used (right-hand panel). Coloured zones show the proportion of the population in each colour class through 21 cycles: red only, green only, yellow (red plus green), white (cells without fluorescence). -- [biorxiv.org]](https://i0.wp.com/astrobiology.com/wp-content/uploads/2026/08/Forging.png?resize=1200%2C718&ssl=1)
[biorxiv.org] A central puzzle in the evolution of individuality is the origin of heredity. Egalitarian transitions integrate formerly independent replicators into a higher-level individual, but this requires the collective to […]
Origin & Evolution of Life
Posted inOrigin & Evolution of Life
Concurrent Phosphite Oxidation And Adenosine Phosphorylation Under Prebiotic Evaporative Conditions
[Journal of Molecular Evolution] Here, we investigate the concurrent oxidation of phosphite and phosphorylation/phosphonylation of adenosine under prebiotically plausible conditions.
Posted inBiosignatures & Paleobiology
Emergence Of Biosignatures On Earth And Implications For Life Detection
[PNAS] Earth’s organic chemical evolution (OCE) from abiotic to prebiotic to biotic provides critical insights that may have implications for how we interpret observations made by life-detection planetary missions.
Posted inBiochemistry & Organic Chemistry
Chemically Modified Sugars As Multifunctional Precursors For Direct, Template-Free Synthesis Of Nanoporous Carbonaceous Materials
[JACS] Carbonaceous solids with pores in the nanometer domain are of great technological importance owing to their amenability to sorption/separation, catalysis, and electrochemical applications.
![Graphical illustration showing planetary bodies (not to scale) where H2O2 has been detected, the major production pathways of H2O2, and its role in a few examples of prebiotic chemical networks. -- [Fundamental Research]](https://i0.wp.com/astrobiology.com/wp-content/uploads/2026/08/Hydrogen-peroxide-1.png?resize=1200%2C716&ssl=1)
Posted inBiosignatures & Paleobiology
Hydrogen Peroxide On Mars And Icy Moons: Implications For The Search For Extraterrestrial Signatures Of Prebiotic Chemistry
[Fundamental Research]. Hydrogen peroxide (H2O2) is increasingly recognized as an important molecule in prebiotic chemistry that potentially had a large impact on life’s early evolution.
Posted inBiosignatures & Paleobiology
Molecular Assembly As A Universal Biosignature Measurable By Mass Spectrometry
[PNAS] Detecting life beyond Earth requires biosignatures that do not depend on the chemistry of known organisms.
Posted inOrigin & Evolution of Life
Re-evaluating Boundary Conditions Of The Concept of Life
[Proceedings IAU] It is argued that a central challenge to the task of developing a foundational model for life lies within the implicit propositions of the Western scientific view.
Posted inExtremeophiles and Extreme Environments
Could Earthquakes Sustain Yellowstone’s Underground Life?
[USGS] When you think of earthquakes, “life-sustaining” might not be the phrase that immediately jumps to mind. If you haven’t experienced the destruction of an earthquake yourself, you’ve certainly seen […]
![Distribution and protein structures of ancestral energy conservation enzymes in bacteria and archaea. For escape as free-living cells, metabolism had to achieve the state of a balanced stoichiometric reaction145, called redox balance in physiology, and the exergonic reactions of electron transfer from H2 to CO2 needed to be coupled to the pumping of ions from the inside of the cell to the outside (chemiosmotic coupling), as in modern cells. Prior to the coupling of CO2 reduction to ion pumping, the natural pH gradient provided by serpentinizing systems (pH 9–11, vs. sea water (pH 6.5146) was harnessable with the help of simple, abiotically synthesized hydrophobics147,148 such as fatty acids, which were recently shown to support the ATP-synthesizing function of a rotor-stator ATPase149. -- [q-bio.PE]](https://i0.wp.com/astrobiology.com/wp-content/uploads/2026/08/Intermediate.png?resize=1200%2C721&ssl=1)
Posted inOrigin & Evolution of Life
Intermediate Stages In The Origin Of Metabolism At A Phosphorylating Hydrothermal Vent
[q-bio.PE] The origin of life required the emergence of metabolism, an autocatalytic network of enzymatic reactions that synthesize amino acids, nucleotides and cofactors. At the origin of metabolism there were […]
![Bold black letters illustrate amino acids that are deduced as early by the approach, while red letters indicate late additions to the alphabet according to the approach (C* implies possible prebiotic synthesis under specific and narrow conditions [4]). Regular black letters represent amino acids that have not been resolved as either early or late by the approach. LUCA: last universal common ancestor; LECA: last eukaryotic common ancestor; rTCA: tricarboxylic acid cycle. -- Trends in Genetics](https://i0.wp.com/astrobiology.com/wp-content/uploads/2026/08/Reconstructing.png?resize=1200%2C720&ssl=1)
Posted inGenomics, Proteomics, Bioinformatics
Reconstructing Ancient Protein Alphabets: What Can We Truly Infer?
[Trends in Genetics] The canonical amino acid alphabet has remained remarkably stable since life’s early stages, yet the factors that shaped its emergence remain debated. Early views emphasized prebiotic availability […]