[University of Notre Dame] In most modern cells, DNA stores the genetic blueprint, and relies on proteins to replicate, repair and build from those blueprints. At the same time, proteins […]
Origin & Evolution of Life
![Outline of construction of plasmids carrying LUCA and E. coli tRNA genes and codon test genes. A LUCA and E. coli tRNA genes. Pairs of tRNA genes from E. coli and LUCA with identical anticodon sequences were synthesized. Primers (Supplementary Table S2) were used to amplify the transcription templates for in vitro synthesis. B Codon test genes. The constructs were based on the pET23a vector. Test genes were inserted between the NdeI and BamHI sites, with the start codons included in the NdeI site. -- [Journal of Molecular Evolution]](https://i0.wp.com/astrobiology.com/wp-content/uploads/2026/07/Resurrecting-tRNAs.png?resize=1200%2C716&ssl=1)
Posted inOrigin & Evolution of Life
Resurrecting tRNAs of the Last Universal Common Ancestor (Commonote) Toward Rebuilding the Ancient Translation System
[Journal of Molecular Evolution] Ancestral sequence reconstruction (ASR) was used to study the evolution of the translational system by inferring tRNA sequences of the Last Archaeal Common Ancestor (LACA), the […]
Posted inAstrogeology
Diverging Mineral Chemistry of Iron and Nickel Throughout Earth’s Changing Redox Conditions Reveals Foundation for Their Evolution as Protein Cofactors
[LIFE] Iron (Fe) and nickel (Ni) were both foundational to early metabolism, yet their biological trajectories diverged as Earth’s surface redox state changed. Here, we integrate mineral chemistry network analysis, […]
![Potential environments for the origin of life and the corresponding roles of minerals. (a) In the deep-sea hydrothermal vent hypothesis, metal sulfides play a critical role in the formation of chemical precursors and building blocks. (b) In terrestrial hot spring, minerals may concentrate and stabilize molecular building blocks, catalyze polymerization under wet–dry cycling conditions, and provide protection against environmental stresses. (c) Extraterrestrial input of organic matter through meteorites, comets and IDPs. Minerals are the carrier and preserver of organic compounds and may possibly take part in the prebiotic synthesis of organic compounds in extraterrestrial environments. (Background images are modified based on AI-generated illustrations.) -- [Fundamental Research]](https://i0.wp.com/astrobiology.com/wp-content/uploads/2026/07/The-role-of-minerals.png?resize=1200%2C717&ssl=1)
Posted inOrigin & Evolution of Life
The Role Of Minerals In Prebiotic Evolution: Implications For Identifying Worlds With The Potential For Life’s Origin
[Fundamental Research] Understanding the origin of life requires explaining how abiotic molecules transitioned into the first living systems within plausible geological settings. Increasing evidence suggests minerals as active participants in […]
Posted inAway Teams & Field Reports
Expedition Led By MBARI Researchers Reveals A Remarkable, And Rare, Form Of Deep-sea Hydrothermal Vents
[MBARI] An international team of researchers, led by MBARI Senior Scientist Aaron Micallef and Schmidt Ocean Institute, has discovered two remarkable fields of hydrothermal vents in the Doldrums Megatransform and […]
Posted inMeteorites & Asteroids
20 Years Later: The ALH 84001 Debate in Context with Viking’s Results. Lessons Learned and Portals Opened
[Astrobiology via PubMed] This article is an anecdotal recap of lessons learned from the ALH 84001 debate in light of the historical and recent debate over the Viking results.
Posted inBiochemistry & Organic Chemistry
Unraveling The Building Blocks Of Earth’s Pigments
[Ohio State] Although they are some of the most widespread substances on Earth, not much is known about eumelanin, or natural organic matter (NOM) — a dark-colored substance formed by […]
Posted inVenus
A Panspermia Origin For Venus Cloud Life
[USRA] Panspermia is the idea that life can originate on one planetary body and then be transferred to other bodies. Impacts are often the suggested method for transfer, as they […]
Posted inNanotechnology & SynBio
Ecological Constraints To Mirror Life
[bioRxiv] Our biosphere exhibits remarkable diversity yet is constrained by universal organizational principles, including molecular homochirality.
Posted inOrigin & Evolution of Life
The Earthling Ovary Blueprint Is Ancient According To Sea Stars
Editor’s note: the genetic innovations that appear over the course of life’s evolution on Earth are often preserved as evolution advances. If it works – then it works. By studying […]