Induced pluripotent stem cells (iPSCs) grown attached as a mat in 2D on Earth as the current state-of-the-art (left) vs. iPSC experimentally grown as spheres in suspension in 3D bioreactors […]
synbio
Genome Modeling And Design Across All Domains Of Life With Evo 2
All of life encodes information with DNA. While tools for sequencing, synthesis, and editing of genomic code have transformed biological research, intelligently composing new biological systems would also require a […]
Recoding A Genome For Programmable Synthetic Proteins
Synthetic biologists from Yale were able to re-write the genetic code of an organism — a novel genomically recoded organism (GRO) with one stop codon — using a cellular platform […]
Extremophile Spinoffs: Bioactive Compounds Identified In Bacteria From The Andes
An article published in the journal Scientific Reports describes how researchers analyzed biofilm produced by bacteria found in the El Medano hot springs, located in Chile in the central Andes, […]
The Extremophile Protein That Revolutionized DNA Sequencing
This game-changing bacterium is called Thermus aquaticus, and it can withstand temperatures as high as 80°C. It’s an example of an extremophile – an organism capable of living in extreme […]
Mapping the Edges of Mass Spectral Prediction: Evaluation of Machine Learning EIMS Prediction for Xeno Amino Acids
Mass spectrometry is one of the most effective analytical methods for unknown compound identification. By comparing observed m/z spectra with a database of experimentally determined spectra, this process identifies compound(s) […]
Extremophiles and Extremophilic Behaviour – New Insights and Perspectives
Extremophiles, throughout evolutionary time, have evolved a plethora of unique strategies to overcome hardships associated with the environments they are found in.
Non-Living Intelligence: Cracking The Code For Materials That Can Learn
It’s easy to think that machine learning is a completely digital phenomenon, made possible by computers and algorithms that can mimic brain-like behaviors.
Expanding the Horizon of the Xeno Nucleic Acid Space
Xeno nucleic acids (XNAs) constitute a class of synthetic nucleic acid analogues characterized by distinct, non-natural modifications within the tripartite structure of the nucleic acid polymers.
Synthetic Cells Emulate Natural Cellular Communication
A research team from the University of Basel has succeeded in synthesizing simple, environmentally sensitive cells complete with artificial organelles. For the first time, the researchers have also been able […]
