[University at Buffalo] It’s one of the origins of life’s chicken-or-the-egg problems: How could RNA have helped give rise to the first cells before there were cells to contain them?
DNA
Posted inOrigin & Evolution of Life
Liquid–liquid Phase Separation As A Driver Of Abiogenesis And Evolution
[Academia Molecular Biology and Genomics] The origin of life may have emerged through physical mechanisms that enable molecular organization and self-assembly.
Posted inExtremeophiles and Extreme Environments
Comparative Genomics Of Space-resilient Chroococcidiopsis Cyanobacteria Reveals A Core Genetic Repertoire Supporting Extreme Tolerance Towards Desert And Non-Earth Conditions
[FEMS Microbes] Desert cyanobacteria of the Chroococcidiopsis genus, due to their remarkable desiccation and radiation tolerance, are considered model candidates in the field of astrobiology.
Posted inGenomics, Proteomics, Bioinformatics
Pinpointing Where Cells First Begin Copying DNA
[Medical Research Council (MRC) Laboratory of Medical Sciences] Every time a cell divides, it must faithfully copy its entire genetic instruction manual. Errors during this process can damage the genome, […]
![a) Biological evolution as stochastic optimization: Initially, wild-type cells x grow up a population. A mutant y grows up a population. The populations x and y compete. The winner (greater population) then fetches more resources. Fitness landscapes at the bottom show how the mutant is an experiment, where the winner decides the next step direction. b) Evolution annotated in terms of the Central Dogma: (Left, green) Wildtype starting point, NA encodes PR, which gives fitness F. (Top, red), Mutation in the blueprint NA, becoming NA’. (Red, green) both NA sequences grow up into populations. (Next) The populations compete for fitness. The winner, Fx now carries with it the winning sequence NAx and protein P Rx. -- [biorxiv.org]](https://i0.wp.com/astrobiology.com/wp-content/uploads/2026/07/RNA-And-Proteins.png?resize=1200%2C720&ssl=1)
Posted inOrigin & Evolution of Life
RNA And Proteins Joined Up At The Origins Of Life: Persistence Is The Point
[biorxiv.org] What drove nucleic acids (NA) to associate with proteins (PR) at the Origins of Life? We reason from polymer physics and the Central Dogma (CD) that the fitness value […]
Posted inExtremeophiles and Extreme Environments
Rising From The Fragments: A Multi-factorial Regulatory Framework Of DNA Damage Response In Deinococcus radiodurans
[Extremophiles] Understanding the coordinated regulation of gene expression in response to environmental challenges is critical for unravelling the resistance strategies of the extremophiles that endure extreme habitats.
Posted inOrigin & Evolution of Life
How Early RNA-based Life May Have Repaired Its Genome
[University of Notre Dame] In most modern cells, DNA stores the genetic blueprint, and relies on proteins to replicate, repair and build from those blueprints. At the same time, proteins […]
Posted inAstrochemistry
Sugar Erythrulose Discovered In Interstellar Space
[Spanish National Research Council (CSIC)] Sugars are key biomolecules in living organisms, as they form the backbone of DNA and RNA and play a fundamental role in metabolic processes. In […]
Posted inBiochemistry & Organic Chemistry, Biophysics, Biosignatures & Paleobiology, Genomics, Proteomics, Bioinformatics, Nanotechnology & SynBio, Press Release, Tricorders & Sensors
Tricorder Tech: A Schematic Of Core Steps In The Enzymatic Synthesis Platform
Editor’s note: If you are on a long term mission or on an away team on another world, you might want your tricorder to be able to do some quick […]
Posted inBiosignatures & Paleobiology, Extremeophiles and Extreme Environments, Genomics, Proteomics, Bioinformatics, Habitable Zones, Mars, Planetary Protection & Biosafety, Press Release
Pathogens Survive Conditions On Extraterrestrial Locations
Micro organisms from our planet could survive on celestial bodies where water is present, such as Mars. That is the conclusion of PhD candidate Tommaso Zaccaria after experiments with simulated […]