Radiation is one of the most pervasive environmental stressors that has profoundly influenced microbial evolution, driving the development of intricate survival strategies in extreme environments.
biotechnology
Artificial Intelligence Aided Design Of Peptides With Custom Secondary Structure Motifs And Reduced Amino Acid Alphabets
Proteins are highly diverse functional polymers where the specific sequence of amino acids, selected from a standard genetically-encoded alphabet of twenty (C20), determines the structure and ultimately the function of […]
StructureMASST: A Search Engine For The Chemistry Of Earth Life
Editor’s note: As we expand outward from Earth to other worlds we are almost certainly going to encounter things we did not expect to find – things that are unlikely […]
Identifying The Limits Of Protein Evolution
The number of known proteins is infinitely small in comparison to the universe of possible proteins which could in theory be realized. Yet these known proteins are the only major […]
Behavioral, Physiological, and Transcriptional Mechanisms of Memory in a Synthetic Living Construct
Synthetic living constructs, which lack the long histories of selection in ecological contexts that shape behaviors of conventional organisms, offer an important complement to traditional studies of learning.
Molecular Adaptations And Engineering Of Extremophiles For Synthetic Biology And Biotechnological Applications
Extremophiles are microorganisms that thrive in environments previously thought to be uninhabitable, including extreme temperature, salinity, pH, pressure, and radiation.
Tricorder Tech: Protein Sequencing Advance Offers New Insights Into Life’s Foundations
Editor’s note: with recent speculation about the potential habitability of other worlds and understanding the processes whereby other biospheres arise and evolve, thought needs to be given to developing sensor […]
NASA Volunteers Study Biofilm Adaptability in Space
Biofilms are communities of microorganisms that stick to one another and also adhere to a nearby surface. They are intricately associated with life on Earth, enabling functions essential to human […]
With Evo 2, AI Can Model And Design The Genetic Code For All Domains Of Life
The DNA foundation model Evo 2, first released in February 2025 as a preprint, is now published in the journal Nature. Trained on the DNA of over 100,000 species across […]
First Genome Sequence And Functional Profiling Of Psychrobacter SC65A.3 Preserved In 5,000-year-old Cave Ice
Introduction: Ancient cryospheric environments may preserve overlooked reservoirs of antimicrobial resistance (AMR) and bioactive potential. This study reports the first whole-genome sequencing and functional characterization of Psychrobacter sp. SC65A.3 isolated […]
