Proteins are built from 20 canonical amino acids. It is interesting to explore whether proteins can be formed from significantly reduced amino acid alphabets.
biorxiv.org
Posted inBiochemistry & Organic Chemistry, Biophysics, Commercial & Private Sector, Genomics, Proteomics, Bioinformatics, Microbiology & Virology, Nanotechnology & SynBio, Status Report
Behavioral, Physiological, and Transcriptional Mechanisms of Memory in a Synthetic Living Construct
Synthetic living constructs, which lack the long histories of selection in ecological contexts that shape behaviors of conventional organisms, offer an important complement to traditional studies of learning.
Posted inAstropharmacy / Biotechnology, Biochemistry & Organic Chemistry, Biophysics, Genomics, Proteomics, Bioinformatics, Gravitational Biology, Life Support Systems, Microbiology & Virology, Microgravity, Nanotechnology & SynBio, Status Report
ExocubeBio: An In-situ Fluidic Platform For Microbial Exposure On The International Space Station
Space-based platforms currently represent the most accurate means to experimentally assess the influence of the space environment on biological systems. However, performing such experiments remains technically challenging and requires highly […]
Posted inBiochemistry & Organic Chemistry, Biophysics, Biosignatures & Paleobiology, Genomics, Proteomics, Bioinformatics, Nanotechnology & SynBio, Status Report
Compositional Memory Matters For Early Molecular Systems
The error catastrophe refers to the proliferation of non-functional molecules in conditions where molecular replication has low accuracy, which is likely to correspond to conditions present at the Origin of […]
Posted inBiochemistry & Organic Chemistry, Biophysics, Genomics, Proteomics, Bioinformatics, Microbiology & Virology, Origin & Evolution of Life, Status Report
Modularity, Ecology, And Theoretical Evolution Of The Ribozyme Body Plan
Ribozymes are relics of molecular life forms from the primitive earth that are embedded within modern genomes across all kingdoms of life. Despite significant knowledge from decades of bioinformatic and […]
Posted inAI - Data - Apps - Cybernetics, Astronauts and Explorers, Genomics, Proteomics, Bioinformatics, Microgravity, Space Life Science, Space Physiology & Medicine, Space Stations, Status Report
ibSLS: A Biobank for Democratizing Access to Multi-Omics Data and Biospecimens from Spaceflight Research
During spaceflight, astronauts are exposed to extreme conditions such as microgravity, cosmic radiation, and confinement, which can cause a wide range of health problems.
Posted inAI - Data - Apps - Cybernetics, Astrochemistry, Astrogeology, Biochemistry & Organic Chemistry, Biophysics, Biosignatures & Paleobiology, Origin & Evolution of Life, Status Report
Prebiotic Resource Constraints And The Origin Of Life: A Linear Logic Framework
The origin of life is a complex scientific problem demanding interdisciplinary approaches. We propose a Linear Logic (LL)-based computational framework to formally evaluate the feasibility of early biochemical pathways across […]
Posted inMicrobiology & Virology, Microgravity, Press Release, Space Life Science, Space Stations
Microgravity Affects The Nervous System And Aging In C. elegans Through Reduced Tactile Stimulation
Space travel is becoming accessible, yet our understanding of how space environment and microgravity (µG) affect biology, physiology, and health remains incomplete.
Posted inAnalog Studies, Arctic / Antarctic / Alpine, Away Teams & Field Reports, Biochemistry & Organic Chemistry, Biosignatures & Paleobiology, Extremeophiles and Extreme Environments, Habitable Zones, Mapping, Geodesy, Cartography, Bathymetry, Microbiology & Virology, Origin & Evolution of Life, ROVs/Submersibles/Diving, Sample Return, Status Report, Water/Hycean Worlds & Oceanography
Aurora Vent Field Is A Hotspot For Microbial Hydrogen Oxidation In The Arctic Ocean
Molecular hydrogen (H2) is a widespread, energetically efficient reductant supporting microbial metabolism across most known ecosystems. Although seafloor hydrothermal vents are major energy providers for H2-oxidizing microorganisms, the diversity of […]
Posted inAnalog Studies, Arctic / Antarctic / Alpine, Away Teams & Field Reports, Extremeophiles and Extreme Environments, Genomics, Proteomics, Bioinformatics, Microbiology & Virology, Polar / Alpine Expeditions, Sample Return, Status Report
Genomic Adaptations Of Novel Halotolerant Bacteria From Extreme North Greenland
Peary Land, northern-most Greenland, is a cold desert region whose soil microbiome remains underexplored. This is the first study to explore the halotolerant soil microbiome of this region with culture-dependent […]