The origin of life is a complex scientific problem demanding interdisciplinary approaches. We propose a Linear Logic (LL)-based computational framework to formally evaluate the feasibility of early biochemical pathways across […]
biorxiv.org
Posted inMicrobiology & Virology, Microgravity, Press Release, Space Life Science, Space Stations
Microgravity Affects The Nervous System And Aging In C. elegans Through Reduced Tactile Stimulation
Space travel is becoming accessible, yet our understanding of how space environment and microgravity (µG) affect biology, physiology, and health remains incomplete.
Posted inAnalog Studies, Arctic / Antarctic / Alpine, Away Teams & Field Reports, Biochemistry & Organic Chemistry, Biosignatures & Paleobiology, Extremeophiles and Extreme Environments, Habitable Zones, Mapping, Geodesy, Cartography, Bathymetry, Microbiology & Virology, Origin & Evolution of Life, ROVs/Submersibles/Diving, Sample Return, Status Report, Water/Hycean Worlds & Oceanography
Aurora Vent Field Is A Hotspot For Microbial Hydrogen Oxidation In The Arctic Ocean
Molecular hydrogen (H2) is a widespread, energetically efficient reductant supporting microbial metabolism across most known ecosystems. Although seafloor hydrothermal vents are major energy providers for H2-oxidizing microorganisms, the diversity of […]
Posted inAnalog Studies, Arctic / Antarctic / Alpine, Away Teams & Field Reports, Extremeophiles and Extreme Environments, Genomics, Proteomics, Bioinformatics, Microbiology & Virology, Polar / Alpine Expeditions, Sample Return, Status Report
Genomic Adaptations Of Novel Halotolerant Bacteria From Extreme North Greenland
Peary Land, northern-most Greenland, is a cold desert region whose soil microbiome remains underexplored. This is the first study to explore the halotolerant soil microbiome of this region with culture-dependent […]
Posted inBiochemistry & Organic Chemistry, Biophysics, Biosignatures & Paleobiology, Genomics, Proteomics, Bioinformatics, Origin & Evolution of Life, Status Report
Emergence Of A Potentially Ancestral ATP-synthesizing Activity Under Prebiotic Amino Acid Constraints
The earliest enzymes are thought to have been composed of the limited amino acid repertoire available on prebiotic Earth. However, how such compositional simplicity shaped catalytic capability remains unclear.
Posted inGenomics, Proteomics, Bioinformatics, Microbiology & Virology, Origin & Evolution of Life, Status Report
Asgard Archaeal Origin Of Microtubules
Eukaryotic cells change their shapes, actively segregate their DNA and contain membrane networks, facilitated by a complex cytoskeleton containing actin filaments, microtubules made from tubulin, and other components.
Posted inAstropharmacy / Biotechnology, Biochemistry & Organic Chemistry, Biosignatures & Paleobiology, Genomics, Proteomics, Bioinformatics, Nanotechnology & SynBio, Press Release
Xeno Amino Acid Alphabets Form Peptides With Familiar Secondary Structure
The central dogma of molecular biology describes how genetic information stored in nucleic acids guides the formation of structured proteins from a single molecular alphabet of twenty amino acids (C20)1,2.
Posted inBiochemistry & Organic Chemistry, Extremeophiles and Extreme Environments, Genomics, Proteomics, Bioinformatics, Microbiology & Virology, Origin & Evolution of Life, Status Report
Archaeal G-Quadruplexes: A Novel Model for Understanding Unusual DNA/RNA Structures Across the Tree of Life
Archaea, a domain of microorganisms found in diverse environments including the human microbiome, represent the closest known prokaryotic relatives of eukaryotes.
Posted inBiochemistry & Organic Chemistry, Biophysics, Genomics, Proteomics, Bioinformatics, Microbiology & Virology, Origin & Evolution of Life, Status Report
The Phylogenetic Context For The Origin Of A Unique Purple-green Photosymbiosis
Symbioses are widespread in nature and have been the source of much evolutionary innovation. While some types of symbioses evolved multiple times across space and time (e.g., oxygenic photosymbioses or […]
Posted inBiogeochemical Cycles & Geobiology, Biophysics, Biosignatures & Paleobiology, Origin & Evolution of Life, Status Report
Did Iron Suppress Eukaryote Emergence and Early Radiation?
The last eukaryotic common ancestor (LECA) is widely thought to have been an oxygen-respiring organism, arising through endosymbiosis when a free-living bacterium became the mitochondrion.