Proteins are highly diverse functional polymers where the specific sequence of amino acids, selected from a standard genetically-encoded alphabet of twenty (C20), determines the structure and ultimately the function of […]
NASA’s Science Mission Directorate (SMD) has released a new Request for Information (RFI) entitled, Private Sector Activities in Astrobiology, Planetary Protection, and Space Biology, seeking expressions of interest from U.S. […]
The origin(s) of life (OoL), which has puzzled scientists for centuries, remains a major scientific challenge in the 21st century.
The origin(s) of life (OoL), which has puzzled scientists for centuries, remains a major scientific challenge in the 21st century. Understanding the processes relevant to the OoL demands theoretical frameworks […]
The scientific study of life’s origins is undergoing a major transition, from a decades-long focus on deep-sea hydrothermal vents toward increasing investigation of hot springs and other chemically dynamic environments […]
Experiments exploring potential emergence-of-life chemistry in a laboratory setting critically depend on simulating realistic early-Earth environments. Such experimental conditions include the implementation of controlled high temperatures and pressures, anoxic gas […]
Recently, plenty research has been done on discovering the role of energy dissipation in biological networks, most of which focus on the relationship of dissipation and functionality.
Here, we derive sufficient conditions for subgraphs supporting irreducible autocatalytic systems in the bipartite König representation of the CRN. On this basis, we develop an efficient algorithm to enumerate autocatalytic […]
We propose a simple and efficient pathway for the formation of precursors to core nucleobases in DNA and RNA using a suite of computational chemistry methods.
The origin of life is commonly discussed within two competing conceptual frameworks: the metabolism-first and information-first hypotheses. While each emphasizes a different defining property of early life, modern biochemistry reveals […]
