Given recent advances in metabolic engineering for rapid growth, extremophiles with novel properties, biological self-assembly properties of tunable materials, and emergent mechanical design principles of biological systems, DARPA is interested […]
Nanotechnology & SynBio
Comparing Earth Life Growth – At Home – And Off World
Induced pluripotent stem cells (iPSCs) grown attached as a mat in 2D on Earth as the current state-of-the-art (left) vs. iPSC experimentally grown as spheres in suspension in 3D bioreactors […]
Extremophile/Astrobiology Spinoff: A Tardigrade Protein May Help Cancer Patients Tolerate Radiation Therapy
About 60 percent of all cancer patients in the United States receive radiation therapy as part of their treatment. However, this radiation can have severe side effects that often end […]
Genome Modeling And Design Across All Domains Of Life With Evo 2
All of life encodes information with DNA. While tools for sequencing, synthesis, and editing of genomic code have transformed biological research, intelligently composing new biological systems would also require a […]
Recoding A Genome For Programmable Synthetic Proteins
Synthetic biologists from Yale were able to re-write the genetic code of an organism — a novel genomically recoded organism (GRO) with one stop codon — using a cellular platform […]
Machinery Behind Bacterial Nanowires Discovered
Almost all living things breathe oxygen to eliminate the excess electrons produced when nutrients are converted into energy. However, most microbes that mitigate pollution and climate change don’t have access […]
Extremophile Spinoffs: Bioactive Compounds Identified In Bacteria From The Andes
An article published in the journal Scientific Reports describes how researchers analyzed biofilm produced by bacteria found in the El Medano hot springs, located in Chile in the central Andes, […]
The Extremophile Protein That Revolutionized DNA Sequencing
This game-changing bacterium is called Thermus aquaticus, and it can withstand temperatures as high as 80°C. It’s an example of an extremophile – an organism capable of living in extreme […]
Mapping the Edges of Mass Spectral Prediction: Evaluation of Machine Learning EIMS Prediction for Xeno Amino Acids
Mass spectrometry is one of the most effective analytical methods for unknown compound identification. By comparing observed m/z spectra with a database of experimentally determined spectra, this process identifies compound(s) […]
Extremophiles and Extremophilic Behaviour – New Insights and Perspectives
Extremophiles, throughout evolutionary time, have evolved a plethora of unique strategies to overcome hardships associated with the environments they are found in.
