NASA Spaceline Current Awareness List #1,109 19 July 2024 (Space Life Science Research Results)

The abstract in PubMed or at the publisher’s site is linked when available and will open in a new window.

Papers deriving from NASA support:

1. 
   Bailey SM, Kunkel SR, Bedford JS, Cornforth MN.The central role of cytogenetics in radiation biology.Radiat Res. 2024 Jul 10. Online ahead of print.PIs: S.M. Bailey, M.N. CornforthJournal Impact Factor: 2.5
   
   Funding: “The authors are indebted to the National Aeronautics and Space Administration (NASA) HRP program for supporting these efforts: 80NSSC21K0679 (MNC) and 80NSSC19K0434 (SMB). SMB, JSB and MNC are cofounders and Scientific Board members of KromaTiD, Inc.”
2. Jahng JWS, Little MP, No HJ, Loo BW Jr, Wu JC.Consequences of ionizing radiation exposure to the cardiovascular system.Nat Rev Cardiol. 2024 Jul 10. Review.PI: J.W.S. Jahng, J.C. WuJournal Impact Factor: 41.7
   
   Funding: “The authors were supported by research grants from the National Institutes of Health (R01 HL126527, R01 HL130020 and R01 HL141851), National Aeronautics and Space Administration through Cooperative Agreement 80ARC022CA003 (J.C.W.) and the Translational Research Institute for Space Health through Cooperative Agreement NNX16AO69A (J.W.S.J.). …”
3. Vasanthakumari P, Romano RA, Rosa RGT, Salvio AG, Yakovlev V, Kurachi C, Hirshburg JM, Jo JA.Pixel-level classification of pigmented skin cancer lesions using multispectral autofluorescence lifetime dermoscopy imaging.Biomed Opt Express. 2024 Jul 9;15(8):4557-83Note: This article may be obtained online without charge.
   
   Journal Impact Factor: 3.4
   
   Funding: “This study was supported by the National Institutes of Health (grants 1R01CA218739, R01GM127696, R01GM152633, R21GM142107, 1R21CA269099) and the Cancer Prevention and Research Institute of Texas (grant RP180588). This study was also supported by the following Brazilian funding agencies: Coordenação de Aperfeiçoamento de Pessoal de Nível Superior – Brasil (CAPES) – Finance Code 001; CNPq-PVE (401150/2014-3 and 314533/2014-1); CNPq-PQ (305795/2016-3) and São Paulo Research Foundation (FAPESP) grants: 2013/07276-1 (CEPOF); 2014/50857-8 (INCT). This work was also partially funded by the Air Force Office of Scientific Research (AFOSR) (FA9550-20-1-0366, FA9550-20-1-0367, FA9550-23-1-0599), and by NASA, BARDA, NIH, and USFDA, under Contract/Agreement No. 80ARC023CA002. …”
4. Letourneau J, Neubert BC, Dayal D, Carrion VM, Durand HK, Dallow EP, Jiang S, Kirtley M, Ginsburg GS, Doraiswamy PM, David LA.Weight, habitual fiber intake, and microbiome composition predict tolerance to fructan supplementation.Int J Food Sci Nutr. 2024 Jul 9;1-11. Online ahead of print.PI: L.A. DavidJournal Impact Factor: 3.9
   
   Funding: “This work was supported by National Institutes of Health grant 1R01DK116187, Office of Naval Research grant N00014-18-1-2616, Translational Research Institute through Cooperative Agreement NNX16AO69A, the Damon Runyon Cancer Research Foundation, and the Center for Gastrointestinal Biology and Disease, School of Medicine, University of North Carolina at Chapel Hill [NIDDK P30DK034987]. This study used a high-performance computing facility partially supported from the North Carolina Biotechnology Center by grant 2016-IDG-1013 (HARDAC+: Reproducible HPC for Next-Generation Genomics).”
5. Haghani NB, Lampel RH, Samuel BS, Chalasani SH, Matty MA.Identification and characterization of a skin microbiome on Caenorhabditis elegans suggests environmental microbes confer cuticle protection.Microbiol Spectr. 2024 Jul 9;e00169-24. Online ahead of print.Note: This article may be obtained online without charge.
   
   Journal Impact Factor: Not available for this journal
   
   Funding: “…NBH was supported by the UCSD Faculty Mentoring Program, the Summer URS Ledell Family Research Scholarship for Science and Engineering, with technical and professional support provided by UCSD’s Research Scholarship Coordinator, Dr. Sophia Tsai Neri. BSS was supported with NIH grant DP2DK116645, NASA grant 80NSSC22K0250, and JGI/DOE grant CSP-503338. SHC was supported by an NIH grant R01MH096881.”
6. Lewandowski BE, Schkurko CM, Miller RS, Valentine RW, Calaway KM, Yang JD, Ebert DJ, Sargsyan A, Byrne V, Walton M, Lemery J, Suresh R, Thompson MS, Easter BD, Lehnhardt KR.Technology modification, development, and demonstrations for future spaceflight medical systems at NASA.Front Space Technol. 2024 Jul 14;5:1384457.Note: This article and an article below (Soto et al.) in the “Other” section are part of Research Topic “Innovation in Medical Space Technology” (https://www.frontiersin.org/research-topics/57838/innovation-in-medical-space-technology/overview). The Research Topic also includes an article from previous Current Awareness List #1,108 https://doi.org/10.3389/frspt.2024.1391200. Additional articles will be forthcoming and may be found in the link to the Research Topic. This article may be obtained online without charge.
   
   Journal Impact Factor: Not available for this journal
   
   Funding: “…Funding for the projects and technologies described in this manuscript and for the labor necessary to write the manuscript was provided by the Exploration Medical Capability Element of the NASA Human Research Program and by the Exploration Medical Integrated Product Team of the NASA Mars Campaign Office.”
7. Kim AW, Swana S, Sarma MS.Evaluating the buffering role of perceived social support and coping resources against the adult mental health impacts of COVID-19 psychosocial stress: A cross-sectional study in South Africa.ADV RES SCI. 2024 Jul 10.PI: M.S. SarmaJournal Impact Factor: Not available for this journal
   
   Funding: “AWK is supported by the Fogarty International Center and National Institute of Mental Health, of the National Institutes of Health under Award Number D43 TW010543. MSS is supported by the Translational Research Institute for Space Health through National Aeronautics and Space Administration Cooperative Agreement NNX16AO69A and the National Institute on Deafness and Other Communication Disorders of the National Institute of Health under Award Number 5T32DC000023-33. …”

Other papers of interest:

1. Deshevaya ÅÀ, Fialkina SV, Shubrailova EV, Smirnov YI.[Microflora investigation in the MIM-2 area of the International Space Station before and after extravehicular activities].Aviakosm Ekolog Med. 2024;Vol. 58(3);Russian.Note: ISS results.
2. Perevedentsev OV, Plotnikov AD.[Application of convolution neural networks in automated primary diagnostics of skin diseases in long-duration space exploration missions].Aviakosm Ekolog Med. 2024;Vol. 58(3);Russian.Note: From the abstract: “Our investigation demonstrated the feasibility to modify the architecture of convolution neural network VGG16 so that it could be used in diagnostics of skin diseases by medical images with an accuracy of no less than 0.88. In the future, this approach could be integrated into a medical care system of space exploration mission for early detection of skin diseases.”
3. Kutko OV, Rykova MP, Antropova EN, Shmarov VA, Zhirova EA, Orlova KD, Sadova ÀÀ, Vlasova DD, Shulguina SM, Lysenko EÀ, Utkin ÊV, Ponomarev SÀ.[Effect of long-term space mission on formation and development of the human T-cell immunity].Aviakosm Ekolog Med. 2024;Vol. 58(3);Russian.
4. Supolkina NS, Yusupova AK, Ryumin II.[Operational psychological support to crews on space missions: History of the evolution, state-of-the-art, and prospects].Aviakosm Ekolog Med. 2024;Vol. 58(3);Russian.Note: From the abstract: “This paper summarizes the experience of psychological monitoring of the Soviet and Russian space crews, outlines the processes of psychological support bringing in the new, constantly changing conditions, and possible associated difficulties.”
5. Dainiak N.Biology of exfoliation of plasma membrane-derived vesicles and the radiation response: Historical background, applications in biodosimetry and cell-free therapeutics, and quantal mechanisms for their release and function with implications for space travel.Radiat Res. 2024 Jul 10. Online ahead of print.
6. David LZ, Hoogeboom M, Endedijk MD, Schraagen JM.Using a digital data analytic tool to capture dynamic change in coordination patterns: An exploratory study of the Apollo 13 mission.Appl Ergon. 2024 Nov;121:104345.Note: From the abstract: “We examine restructuring in coordination patterns during NASA’s Apollo 13 Mission, revealing significant shifts from stable, long-duration ‘coordination hubs’ in routine operations to shorter-duration patterns during a crisis situation.”
7. Nelson AM, Lacinski RA, Steller JG.Spaceflight-associated pain.Curr Opin Anaesthesiol. 2024 Jun 12. Online ahead of print.
8. Pirri C, Pirri N, Stecco C, Macchi V, De Caro R, Porzionato A.Optimizing healthcare in space: The role of ultrasound imaging in medical conditions.J Ultrasound. 2024 Jul 12. Review.
9. Smith MB, Chen H, Oliver BGG.The lungs in space: A review of current knowledge and methodologies.Cells. 2024 Jul 6;13(13):1154. Review.Note: This article is part of Special Issue “Cells in Space and on Earth” (https://www.mdpi.com/journal/cells/special_issues/GP50606408) and may be obtained online without charge.
10. Özdemir V.Toward next-generation phenomics: Precision medicine, spaceflight, astronaut omics, and beyond.OMICS: A Journal of Integrative Biology. 2024 Jul 17. Online ahead of print.
11. Wang Y, Li C, Wang R, Zhao X, Pan Y, Zhang Q, Li S, Fan J, Wang Y, Sun X.PIEZO1 promotes the migration of endothelial cells via enhancing CXCR4 expression under simulated microgravity.Int J Mol Sci. 2024 Jul 1;25(13):7254.Note: A 2D-clinostat was used in this study. This article is part of Section “Molecular Biology” (https://www.mdpi.com/journal/ijms/sections/Molecular_Biology) and may be obtained online without charge.
12. Liu S, Ma X, Chen Y, Zhao Y, Luo R, Wu Z, Li Y, Qian Y, Wang W, Dong S, Zhou Z, Li S, Xiao Y, Zhu X, Tian Y, Guo J.Multiplex influences on vigilance and biochemical variables induced by sleep deprivation.Front Sports Act Living. 2024 Jun 27;6:1412044.Note: This article is part of Section “Circadian Rhythm and Performance in Sports” (https://www.frontiersin.org/research-topics/63481/circadian-rhythm-and-performance-in-sports/overview) and may be obtained online without charge.
13. Schwoerer AP, Biermann D, Ehmke H.Ventricular unloading causes prolongation of the QT interval and induces ventricular arrhythmias in rat hearts.Front Physiol. 2024 Jul 2;15:1346093.Note: From the abstract: “Rat hearts were unloaded using the heterotopic heart transplantation. The ECG of unloaded and of control hearts were telemetrically recorded over 56 days resulting in >5 × 106 cardiac cycles in each heart. Long-term electrical remodeling was analyzed using a novel semi-automatic arrhythmia detection algorithm.” This article may be obtained online without charge.
14. Soto E, Vega R.Use of galvanic vestibular stimulation device as a countermeasure for microgravity effects in spaceflight.Front Space Technol. 2024 Jul 4;5:1422868.Note: This article and an article above (Lewandowski et al.) in the “NASA” section are part of Research Topic “Innovation in Medical Space Technology” (https://www.frontiersin.org/research-topics/57838/innovation-in-medical-space-technology/overview). This article may be obtained online without charge.

astrobiology, space life science, microgravity,