NASA Spaceline Current Awareness List #1,150 23 May 2025 (Space Life Science Research Results)

The abstract in PubMed or at the publisher’s site is linked when available and will open in a new window.

Papers deriving from NASA support:

1. Hill MS, Minnis VR, Simpson AC, Salas Garcia MC, Bone D, Chung RK, Rushton E, Hameed A, Rekha PD, Gilbert JA, Venkateswaran K.Genomic description of Microbacterium mcarthurae sp. nov., a bacterium collected from the International Space Station that exhibits unique antimicrobial-resistant and virulent phenotype.mSystems. 2025 May 20;e0053725. Online ahead of print.PI: J.A. GilbertNote: ISS results. This article may be obtained online without charge.
   
   Journal Impact Factor: 6.4
   
   Funding: “The research was funded by a 2019 Space Biology Grant 80NSSC19K1604.”
2. Adkins AM, Luyo ZNM, Boden AF, Heerbrandt RS, Britten RA, Wellman LL, Sanford LD.Neuroinflammatory signaling and immune cell infiltration differ in brains of rats exposed to space radiation and social isolation.Life. 2025 May 6;15(5):747.PI: L.D. SanfordNote: This article is part of Special Issue “Feature Paper in Physiology and Pathology: 2nd Edition” (https://www.mdpi.com/journal/life/special_issues/0E97QL71F8) and may be obtained online without charge.
   
   Journal Impact Factor: 3.2
   
   Funding: “Support for this project came from the National Aeronautics and Space Administration (NASA) [grant number CBS VNSCOR 80NSSC19K1582] to L.D.S. and a supplemental NASA HRP Augmentation Award to A.M.A.”
3. Akter Tani T, Scouten A, Ortiz E, McLean RJC, Tešić J.Automated corrosion identification in metal imagery: Traditional vs. deep learning.Advances in Visual Computing. 2025.PI: R.J.C. McLeanNote: This article is a conference proceeding published in peer-reviewed publication series Advances Visual Computing.
   
   Journal Impact Factor: 2.3
   
   Funding: “This work has been partially supported by the NSF # 2224449 grant, RJCM is supported by NASA grant 80NSSC22K1361, and the Texas State University Research Enhancement Program grant.”
4. Carter KJ, Laurie SS, Warthen KG, Sater SH, Martin BA, Feng CM, Young M, Hasan KM, Kramer LA, Macias BR.Normal variation in brain volumetrics, CSF dynamics, and ocular structures from magnetic resonance images of healthy participants over two years.J Appl Physiol (1985). 2025 May 21. Online ahead of print.Note: This article may be obtained online without charge.
   
   Journal Impact Factor: 3.3
   
   Funding: “NASA Human Research Program Directed Research.”
5. Chen Y, Liu P, Sabo A, Guan D.Human genetic variation determines 24-hour rhythmic gene expression and disease risk.Nat Commun. 2025 May 8;16(1):4270.Note: This article may be obtained online without charge.
   
   Journal Impact Factor: 14.7
   
   Funding: “This work is supported by R37CA296577, K01-DK125602, Cancer Prevention and Research Institute of Texas (RR210029), V Foundation (V2022-026), and pilot award DK056338, P30 CA125123, TRISH NNX16AO69A, and H-NORC to D.G., as well as the American Liver Foundation Postdoctoral Research Fellowship Award granted to Y.C. The VIVA cohort collection, phenotyping, and variant identification were supported by NIH (U54 HG003273-12 and 1UM1HG008898, R01 DK59264, DK092238 and DK080457) and USDA/ARS under Cooperative Agreement 58-6250-5100.”
6. Clément G, Kuldavletova O, Quarck G, Macaulay TR, Wood SJ, Denise P.Perception of body translation amplitude in altered gravity during parabolic flight.Front Physiol. 2025 May 21;16:1595836.Note: This article may be obtained online without charge.
   
   Journal Impact Factor: 3.2
   
   Funding: G. Clément, T.R. Macaulay, and S.J. Wood are affiliated with NASA Johnson Space Center.
7. Harrington J, Cheburkanov V, Kizilov M, Kulagin I, Petrov GI, Yakovlev VV.Highly sensitive, low-cost deep-UV resonant raman microspectroscopy systems.Chemistry-Methods. 2025 Apr 21;2500006. Online ahead of print.Note: This article may be obtained online without charge.
   
   Journal Impact Factor: 6.1
   
   Funding: “J.T.H. received funding support via the SMART Scholarship-forService Program. V.V.Y. received partial funding support from the Air Force Office of Scientific Research (AFOSR) (grants FA9550-20-1-0366, FA-9555-23-1-0599), the National Institutes of Health (NIH) (grants R01GM127696, R01GM152633, R21GM142107, R21CA269099), and NASA, BARDA, NIH, and USFDA, under Contract/Agreement No. 80ARC023CA002.”
8. Lawler J, Kim J, Othman M, Kamal K, Fluckey J.The sirtuin-1 agonist SRT2104 mitigates redox signaling and nNOS translocation in unloaded skeletal muscle.Physiology. 2025 May 12;40(S1):1343.PI: J. LawlerJournal Impact Factor: 5.3
   
   Funding: “Supported by NASA (80NSSC19K0432, NNX80NSSC17K0118, NNX13AE45G), NSBRI, Huffines Institute, Fight DMD.”
9. Othman M, Kim J, Kamal K, Lawler J.RANKL elevation contributes to skeletal muscle myopathy in aging: Unveiling of novel mechanisms.Physiology. 2025 May 12;40(S1):0567.PI: J. LawlerJournal Impact Factor: 5.3
   
   Funding: “Supported by NASA (80NSSC19K0432, NNX80NSSC17K0118, NNX13AE45G), NSBRI, and Huffines Institute, FightDMD.”
10. Plante I, Daniels V, Young M, Gaza R, Wu H, Reichard JF.The long-term stability of solid-state oral pharmaceuticals exposed to simulated intravehicular space radiation.npj Microgravity. 2025 May 17;11(1):17.Note: This article may be obtained online without charge.
    
    Journal Impact Factor: 5.1
    
    Funding: “This work was performed under NASA contract NNJ15HK11B.”
11. Robin A, Zaman SY, Reinarz C, Lawson K, McKnight J, Navasiolava N, Custaud M, Haddad L, Zawieja D, Diaz-Artiles A.Ocular and jugular gravitational dose-response curves during hypovolemia: Preliminary results.Physiology. 2025 May 12;40(S1):0116.PI: A. RobinJournal Impact Factor: 5.3
    
    Funding: “This work is supported by the Translational Research Institute for Space Health through NASA Cooperative Agreement NNX16AO69A.”
12. Seyedmadani K, Tucker KA, Anderson MR, Akay YM, Akay M, Stone LS.Effects of binocularity and eye dominance on visually-driven ocular tracking.Front Neurosci. 2025 Apr 30;19:1504628.Note: This article may be obtained online without charge.
    
    Journal Impact Factor: 3.2
    
    Funding: “This work was supported by the National Aeronautics and Space Administration (NASA) provided funding for this research through a Human Research Program ISFM grant (to LS) and Space Technology Mission Directorate Grant 80NSSC19M0186 (to KS).”
13. Weinrich M, Neto OP, Wang Y, Abbott R, Walsh M, Diaz-Artiles A, Kennedy DM.Accuracy and stability in non-immersive VR: How display type and body position influence motor performance.Hum Mov Sci. 2025 Jun;101:103360.PI: A. Diaz-ArtilesNote: This article may be obtained online without charge.
    
    Journal Impact Factor: 1.6
    
    Funding: “This research was supported by the NASA Human Research Program, Grant number 80NSSC20K1499.”

Other papers of interest:

1. Fournier R, Greaves DK, Shoemaker JK, Arbeille P, Hughson RL, Robertson AD.Cerebrovascular pulsatility following long duration spaceflight is associated with changes in pulse pressure and carotid artery stiffness.Exp Physiol. 2025 May 19. Online ahead of print.Note: ISS results. This article may be obtained online without charge.
2. Kumar R, Waisberg E, Ong J, Paladugu P, Sporn K, Chima K, Amiri D, Zaman N, Tavakkoli A.Precision health monitoring in spaceflight with integration of lower body negative pressure and advanced large language model artificial intelligence.Life Sci Space Res. 2025 May 20. Online ahead of print.Note: This article is an opinion/position paper.
3. Sun Y, Liu S, Chen L, Zhou Z, Ma M, Li J, Lu Y, Shi Y, Yao T, Feng R, Lu Q, Qassadi F, Williams PM, Monaghan TM, Wang G, Zhu Z, Li X.Spaceflight redefines aging-associated microbiota.iMeta. 2025 Mar;e70023. Online ahead of print.Note: This is a correspondence and may be obtained online without charge.
4. Cutigni M, Cucina G, Galante E, Cerri M, Bizzarri M.Microgravity impairs endocrine signaling and reproductive health of women. A narrative review.Front Physiol. 2025 May 13;16:1558711.Note: This article is part of Research Topic “Exploring Frontiers: Astroparticle, Space Science and Public Health for Future Crewed Space Missions” (https://www.frontiersin.org/research-topics/63490/exploring-frontiers-astroparticle-space-science-and-public-health-for-future-crewed-space-missions/overview). The Research Topic also includes articles from previous Current Awareness Lists #993 https://doi.org/10.3389/fpubh.2022.862598, #1,027 https://doi.org/10.3389/fspas.2022.949432, #1,049 https://doi.org/10.3389/fspas.2023.1117811, #1,124 https://doi.org/10.3389/fphys.2024.1486767, #1,127 https://doi.org/10.3389/fphys.2024.1482860, #1,137 https://doi.org/10.3389/fimmu.2025.1538421, #1,146 https://doi.org/10.3389/fphys.2025.1558625, and #1,149 https://doi.org/10.3389/fphys.2025.1558711. This article may be obtained online without charge.
5. Sánchez-Lozano J, Peña-Asensio E, Bickel VT, Kring DA.Prioritizing astronaut traverses on the Moon: A multi-criteria decision-making approach.Acta Astronaut. 2025 Apr;229:77-89.Note: From the abstract: “Properly designed astronaut traverses are decisive for the science return and safety of crewed lunar missions to the Moon. Their development and planning are challenged by numerous parameters involved and the difficulty of determining their relative importance. Investigating the potential of Multi-Criteria Decision-Making (MCDM) techniques for lunar exploration within the context of Artemis III, this paper demonstrates the effective application of the well-established Analytic Hierarchy Process (AHP) and the Technique for Order Preference by Similarity to Ideal Solution (TOPSIS).”
6. Meinke A, Baez AL, Wiesmann N, Ullrich O, Green DA, Egli M, Swanenburg J.Adaptation of thoracic and lumbar curvature and spinal muscle activity under changing gravity.Front Physiol. 2025 May 20;16:1549249.Note: This article may be obtained online without charge.

Astrobiology, space biology, space life science, space medicine, microgravity,