During the microbial surveillance of the International Space Station (ISS) in April 2018, four Gram-stain positive bacterial strains, designated as F6_8S_P_2BT, F6_8S_P_3A, F6_8S_P_3B and F6_8S_P_3C, belonging to the genus Microbacterium […]
sequencing
Microbial Exoenzymes Catalyzed The Transition To An Oxygenated Earth
Microbial exoenzymes—extracellular enzymes secreted to degrade complex organic polymers— are essential for recycling carbon and nutrients, thus sustaining primary productivity in today’s oceans.
Earth BioGenome Project Accelerates Efforts To Genetically Map Life On Earth
Published in Frontiers in Science, this is the new ambition of the Earth BioGenome Project (EBP)—a global network of scientists sequencing the genomes of Earth’s eukaryotes. Its goal? To create […]
Raiding Nature’s Genetic Toolbox For UV-C Resistance By Functional Metagenomics
As we assess the habitability of other worlds, we are limited by being able to only study terrestrial life adapted to terrestrial conditions.
Tricorder Tech: Unlocking the Full Potential of Nanopore Sequencing: Tips, Tricks, and Advanced Data Analysis Techniques
Editor’s note: If we aspire to mount expeditions to new worlds and then embrace the task of characterizing and quantifying whatever life forms we find, the ability to map and […]
Simulating 500 Million Years Of Evolution With A Language Model
More than three billion years of evolution have produced an image of biology encoded into the space of natural proteins.
The Extremophile Protein That Revolutionized DNA Sequencing
This game-changing bacterium is called Thermus aquaticus, and it can withstand temperatures as high as 80°C. It’s an example of an extremophile – an organism capable of living in extreme […]
Protocell Effects on RNA Folding, Function, and Evolution
Creating a living system from nonliving matter is a great challenge in chemistry and biophysics. The early history of life can provide inspiration from the idea of the prebiotic “RNA […]
Tricorder Tech: A Nanopore Diagnostic Tool Breakthrough Had Multiple Applications
Editor’s note: Nanopore technology has been used multiple times on the International Space Station to try and help elucidate changes in genomic function during exposure to conditions of spaceflight. This […]
CABO-16S: A Combined Archaea, Bacteria, Organelle 16S Database for Amplicon Analysis of Prokaryotes and Eukaryotes in Environmental Samples
Identification of both prokaryotic and eukaryotic microorganisms in environmental samples is currently challenged by either the burden of additional sequencing required to obtain both 16S and 18S rRNA sequences or […]
