Proteome Archives

Comparative analysis of minimum energetic costs for cellular synthesis across different organisms at different temperatures calculated using synercell.

Biochemistry & Organic Chemistry, Biophysics, Genomics, Proteomics, Bioinformatics, Status Report

The Minimum Energy Required To Build A Cell

by Keith CowingMarch 27, 2024March 27, 2024

Understanding the energy requirements for cell synthesis accurately and comprehensively has been a longstanding challenge. We introduce a computational model that estimates the minimum energy necessary to build any cell […]

Extended Data Fig. 5. Heat maps showing major metabolic potential functions and KEGG pathways for individual Halobacteria MAGs assembled from north Danakil hypersaline ecosystems. a, Presence (blue)-absence (white) of metabolic functions as inferred by Metabolic G in Danakil MAGs and representative GTDB genomes of Halobacteria. b, Modules of KEGG pathways identified in Halobacteria MAGs and GTDB reference genomes (outgroup). The blue color intensity indicates the completeness of the respective pathway (intense, complete). The names of our MAGs are highlighted in red. Aa, amino acid. -- biorxiv.org

Analog Studies, Atmospheres, Climate, Weather, Away Teams & Field Reports, Biochemistry & Organic Chemistry, Biogeochemical Cycles & Geobiology, Biophysics, Biosignatures & Paleobiology, Extremeophiles and Extreme Environments, Fossils & Paleontology, Genomics, Proteomics, Bioinformatics, Habitable Zones, Lava / magma ocean / Volcanic Worlds, Microbiology & Virology, Status Report

Extremely Acidic Proteomes And Metabolic Flexibility In Bacteria And Highly Diversified Archaea Thriving In Geothermal Chaotropic Brines

by Keith CowingMarch 17, 2024November 21, 2025

Few described archaeal, and fewer bacterial, lineages thrive at salt-saturating conditions, such as solar saltern crystallizers (salinity above 30%-w/v).