[biorxiv.org] Biological individuals on Earth today are cellular, but the simplest cells are too complex to have arisen spontaneously.
origin of life
The Abiotic Background: Challenges and Opportunities in the Search for Evidence of Life Beyond Earth
[Astrobiology (Journal) via PubMed]. The “Exploring the Abiotic Background for Life Detection“ workshop was convened between March 31, 2025, and April 3, 2025, at the Carnegie Institution for Science in […]
Deep Shifts In Evolutionary Rate Trajectories Of Ancient Bacterial Genes
[biorxiv.org] Reconstruction of ancestral gene repertoires from extant genomes captures only the genes that survived; those lost from the record are invisible. Among the genes that did persist, selective pressures […]
The History Of Enzyme Evolution Embedded In Metabolism
[PNAS]. Whereas phylogenetic reconstructions are a primary record of protein evolution, it is unknown whether the deep history of enzymes is encoded at higher levels of biological organization.
Structure Of An RNA polymerase Ribozyme Replication Complex
[biorxiv.org] Life began with the emergence of a molecule that could replicate its own genetic material, a task plausibly mediated by an RNA-dependent RNA polymerase ribozyme.
Sea Ice As An Origin Of Life Location For Hycean And Ocean Worlds
[astro-ph.EP] Water worlds with potential deep oceans are at the forefront of currently observable exoplanetary habitability.
Carbon and Sulfur Isotopes of Microfossils and Pyrites from Neoarchean Cherts: Microbial Diversity in an Ancient Deep-Marine Environment
[Astrobiology (Journal) via PubMed] The 2.52 Ga Gamohaan Formation in South Africa offers critical insights into microbial ecosystems that inhabited deep-marine environments during the late Archean.
Auroral Belts As Magnetically Localized Reactors For Prebiotic Chemistry On Early Earth
[Biosystems] Most models of prebiotic chemistry emphasize globally distributed or widely acting energy sources, including ultraviolet radiation, lightning, impacts, and energetic particles.
The Emergence Of Life In The Light Of Evolution
[q-bio.PE] The origin of life is often framed primarily as a chemical problem, yet life s defining feature is evolution.
ReactionAtlas: Ab Origine Exploration Of Chemical Reaction Networks With Machine Learning
[cs.LG] Mapping a chemical reaction network, the graph of minima and transition states (TS) and the elementary reactions connecting them, is the natural language of chemistry, from catalysis to combustion […]
