Although a large fraction of Earth’s volume and most places beyond the planet lack life because physical and chemical conditions are too extreme, intriguing scientific questions are raised in many […]
biophysics
Nitrogenase Structural Evolution Across Earth’s History
Life on Earth is more than 3.5 billion years old—nearly as old as the age of the planet. Over this vast expanse of time, life and its biomolecules adapted to […]
Early Ocean World Chemistry: Prebiotic Nucleoside Phosphorylation in a Simulated Deep-Sea Supercritical Carbon Dioxide-Water Two-Phase Environment
Prebiotic synthesis of complex organic molecules in water-rich environments has been a long-standing challenge. In the modern deep sea, emission of liquid CO2 has been observed in multiple locations, which […]
Experimentally Measured Assembly Indices Are Required To Determine The Threshold For Life
Assembly theory (AT) aims to distinguish living from non-living systems by explaining and quantifying selection and evolution.
Astrochemistry: The Mystery of Life’s Handedness Deepens
The mystery of why life uses molecules with specific orientations has deepened with a NASA-funded discovery that RNA — a key molecule thought to have potentially held the instructions for […]
Synthetic Cells Emulate Natural Cellular Communication
A research team from the University of Basel has succeeded in synthesizing simple, environmentally sensitive cells complete with artificial organelles. For the first time, the researchers have also been able […]
Creating A Simplified Form Of Life
It is one of the most fundamental questions in science: how can lifeless molecules come together to form a living cell? Bert Poolman, Professor of Biochemistry at the University of […]
Prebiotic Gas Flow Environment Enables Isothermal Nucleic Acid Replication
Nucleic acid replication is a central process at the origin of life. On early Earth, replication is challenged by the dilution of molecular building blocks and the difficulty of separating […]
A Bayesian Analysis Of The Probability Of The Origin Of Life Per Site Conducive to Abiogenesis
The emergence of life from nonlife, or abiogenesis, remains a fundamental question in scientific inquiry. In this article, we investigate the probability of the origin of life (per conducive site) […]
New Study Sheds Light on Ancient Protoribosome and its Role in Early Life Evolution
Scientists have uncovered new insights into the protoribosome, a molecular fossil within the ribosome, which plays a key role in the origin of life on Earth. This research, published in […]
