Protoribosome Archives

Graphical abstract -- Nucleic Acids Research

Biochemistry & Organic Chemistry, Biophysics, Biosignatures & Paleobiology, Fossils & Paleontology, Genomics, Proteomics, Bioinformatics, Origin & Evolution of Life, Press Release

New Study Sheds Light on Ancient Protoribosome and its Role in Early Life Evolution

by Keith CowingOctober 2, 2024October 2, 2024

Scientists have uncovered new insights into the protoribosome, a molecular fossil within the ribosome, which plays a key role in the origin of life on Earth. This research, published in […]

Secondary structure of the tt_A1P1 construct predicted by mfold (Zuker, 2003). With a ΔG of -64.30 Kcal/mol. Thermus thermophilus numbering system is used. According to this prediction base paring shift occur in H74, H89 and H90. The overall shape of H90 has grown by at least three base pairs at the beginning of the helix compared to the secondary structure of the extant ribosome. -- PNAS

Genomics, Proteomics, Bioinformatics, Origin & Evolution of Life, Status Report

How To Build A Protoribosome

by Keith CowingApril 1, 2023April 1, 2023

NASA-supported scientists have reexamined some previous assumptions about how the ribosome in living cells is constructed. The ribosome is a large molecule found in all living cells that catalyzes the […]