[biorxiv.org] The genetic code is the rule that (apart from minor modifications [1, 2]) is used by all contemporary life on Earth to translate genes into proteins. It is summarized […]
protein
Posted inNanotechnology & SynBio
Designing Protein Structures From Natural Language
[cs.LG] A central challenge in de novo protein design is generating proteins with desired structural and functional properties.
Posted inOrigin & Evolution of Life
Computational Modeling Of An RNA-peptide World
[biorxiv.org] Emergence and evolution of functional RNA and protein structures are the central problems for understanding the origin of life.
Posted inBiophysics
How A Deep-sea Protein Adapts To An Extreme Environment
[Kyushu University] Life in the deep sea is under immense pressure—literally. Such extreme conditions can disrupt the delicate structures of proteins essential to life. Yet somehow, the proteins in deep-sea […]
Posted inOrigin & Evolution of Life
The History Of Enzyme Evolution Embedded In Metabolism
[PNAS]. Whereas phylogenetic reconstructions are a primary record of protein evolution, it is unknown whether the deep history of enzymes is encoded at higher levels of biological organization.
Posted inOrigin & Evolution of Life
Prebiotic Cationic Amino Acids Support Formation Of An Ancient Protein Fold
[biorxiv.org] The evolutionary basis for the selection of the standard proteinogenic amino acids remains elusive, particularly for the long cationic amino acids, lysine and arginine, which were likely scarce in […]
![A symbiotic scenario for co-evolution of the ribosome and the replicase. Two variations of the scenario are depicted, whereby the peptidyltransferase center (PTC) and the replicase (REP) ribozymes are encoded by distinct (A) or the same (B) RNA molecule. The figure depicts three major stages of cellular evolution from the primordial RNA world (left) to the intermediate RNA-protein world (center) and the last universal cellular ancestor (LUCA, right). The major events occurring during each stage are briefly described in the corresponding information boxes at the bottom of the figure. -- [q-bio.PE]](https://i0.wp.com/astrobiology.com/wp-content/uploads/2026/08/The-selfish.png?resize=1200%2C712&ssl=1)
Posted inGenomics, Proteomics, Bioinformatics
The Selfish Ribosome
[q-bio.PE]. The ribosome is responsible for protein synthesis in all cells, and is the largest energy consumer in the cell.
Posted inAstrogeology
Diverging Mineral Chemistry of Iron and Nickel Throughout Earth’s Changing Redox Conditions Reveals Foundation for Their Evolution as Protein Cofactors
[LIFE] Iron (Fe) and nickel (Ni) were both foundational to early metabolism, yet their biological trajectories diverged as Earth’s surface redox state changed. Here, we integrate mineral chemistry network analysis, […]
Posted inBiochemistry & Organic Chemistry
Unraveling The Building Blocks Of Earth’s Pigments
[Ohio State] Although they are some of the most widespread substances on Earth, not much is known about eumelanin, or natural organic matter (NOM) — a dark-colored substance formed by […]
Posted inAstrochemistry, Astronomy & Telescopes, Biochemistry & Organic Chemistry, Biogeochemical Cycles & Geobiology, Biophysics, Biosignatures & Paleobiology, Genomics, Proteomics, Bioinformatics, Habitable Zones, Imaging & Spectroscopy, Origin & Evolution of Life, Press Release, Water/Hycean Worlds & Oceanography
Before The Aliens, The Amino Acids
Before any wrinkled, wide-eyed creature from a distant civilization asks to be taken home, the first success in the search for life beyond Earth might be more prosaic. A clue […]