phospholipid membrane Archives

A simplified illustration of the model. It depicts a cross-section of a spherical phospholipid vesicle, highlighting its membrane with hydrophilic heads and hydrophobic tails. Racemic d- and l-ribose (green) can both penetrate the membrane and capture the PO groups, but d-ribose undergoes this process more quickly and is preferentially trapped (purple) inside the vesicle. --Life

Astrochemistry, Biochemistry & Organic Chemistry, Biophysics, Biosignatures & Paleobiology, Genomics, Proteomics, Bioinformatics, Status Report

Stereoselective Phosphorylation of d-Ribose as a Driver of Life’s Homochirality

by Keith CowingJune 1, 2026June 1, 2026

Life demonstrates remarkable homochirality of its major building blocks: nucleic acids, amino acids, sugars, and phospholipids. Phospholipid bilayer vesicles (liposomes) are formed at the water/air interface from Langmuir layers and […]

Artistic depiction of liposome formation and evolution. Liposomes formed on the surface of the Archean water pools are destroyed by Solar UV unless they acquire two adaptive traits – the heavy content that sinks the liposomes to the bottom of the pool and facilitates protection from UV, and the formation of resilient autocatalytic membrane composition that ensures liposomal survival, fusion, fission, and mutation of the components, thus providing liposomes adaptation and persistence. -- q-bio.PE

Astrochemistry, Biochemistry & Organic Chemistry, Biophysics, Biosignatures & Paleobiology, Genomics, Proteomics, Bioinformatics, Meteorites & Asteroids, Microbiology & Virology, Origin & Evolution of Life, Status Report

Heuristic Model On The Origin Of The Homochirality Of Life

by Keith CowingJanuary 2, 2026January 3, 2026

Life demonstrates remarkable homochirality of its major building blocks: nucleic acids, amino acids, sugars, and phospholipids. We propose a mechanism that places the root of life homochirality in the formation […]