We propose a simple and efficient pathway for the formation of precursors to core nucleobases in DNA and RNA using a suite of computational chemistry methods.
organic chemistry
A Clue For The Hen And Egg Question: The Simultaneous Formation Of Uracil And Amino Acids Under Simulated Hadean Conditions
The origin of life is commonly discussed within two competing conceptual frameworks: the metabolism-first and information-first hypotheses. While each emphasizes a different defining property of early life, modern biochemistry reveals […]
New Method Sharpens The Search For Alien Biology
For decades, the search for life beyond Earth has revolved around a key question: What molecules should scientists be looking for on other planets or moons?
Detecting Fundamental Chiral Biosignatures in the Ultraviolet Polarization Spectrum
Chiral molecules are ubiquitous and necessary for life as we know it. In extant life, the amino acid and sugar constituents of proteins and biopolymers consist of only one enantiomer.
From Gas To Stars Along The Spiral Wave: CO, HCN, And Star Formation Variations Across The Spiral Arms In NGC 4321 And M51
Molecular clouds form stars from the interstellar medium via gravitational collapse, following a sequence from low-density gas to high-density cores and eventually the formation of stars.
New Sulfur-dependent Ecosystem In A Gas Vent In The Depths Of The Chilean Pacific
Unlike most similar emanations described to date, this one shows no evidence of methane emission or consumption. The absence of this molecule and its abundance of sulfur make it a […]
Modeling The UV-photon Irradiation Of CS2-bearing Ices In The Laboratory With The pyRate Gas-grain Astrochemical Code. New Insights Into The Missing Sulfur Problem
Observations indicate that the total abundance of S-bearing species in dense clouds is orders of magnitude lower than the cosmic sulfur abundance.
The Formation of Glycolamide on Interstellar Ices
For decades, scientists have searched interstellar space for the chemical seeds of life. In this issue of ACS Central Science, Kaiser and co-workers (1) offer a striking advance in that […]
Early Life On Earth Relied On A Surprisingly Scarce Metal: Molybdenum
A new study from researchers at the University of Wisconsin–Madison shows that 3.4 billion years ago, life on Earth relied on a metal called molybdenum, despite its limited availability at […]
Shedding Light On How Hydrogen Cyanide Formed On Early Earth
Manganese dioxide can convert amino acids into hydrogen cyanide (HCN) without requiring methane, solving a long-standing puzzle about the origin of this key prebiotic molecule on early Earth, as reported […]
