Krebs cycle Archives

Astrochemistry, Biochemistry & Organic Chemistry, Biophysics, Biosignatures & Paleobiology, Genomics, Proteomics, Bioinformatics, Status Report

Astrochemistry: Abiotic Origin Of Citric Acid Cycle Intermediates

by Keith CowingJuly 8, 2025September 18, 2025

The molecular framework for protometabolism-chemical reactions in a prebiotic environment preceding modern metabolism-has remained unknown in evolutionary biology.

Photo of Nebula NGC 1333. The James Webb telescope detected interstellar ice there, which could be the origin of stars and planets. The study shows that this ice was apparently also behind the formation of organic molecules, including all intermediaries in the Krebs cycle. Credit © ESA/Webb, NASA & CSA, A. Scholz, K. Muzic, A. Langeveld, R. Jayawardhana Larger image

Astrochemistry, Astronomy & Telescopes, Biochemistry & Organic Chemistry, Biophysics, Biosignatures & Paleobiology, Imaging & Spectroscopy, Interstellar, Origin & Evolution of Life, Panspermia, Status Report

Abiotic Origin Of Citric Acid Cycle Intermediates

by Keith CowingApril 22, 2025

The molecular framework for protometabolism—chemical reactions in a prebiotic environment preceding modern metabolism—has remained unknown in evolutionary biology. Mono-, di-, and tricarboxylic acids that comprise contemporary metabolism, such as the […]