![These high-resolution pre-catalysis RNA Pol II EC structures also define the reaction-ready configuration of a complete active site. The 1.96 Å cryo-EM map reveals an unambiguous density of Adenosine triphosphate (ATP) substrate with a chair-like triphosphate conformation that is precisely coordinated with two Mg2+ ions. [Full video] Molecular Cell](https://i0.wp.com/astrobiology.com/wp-content/uploads/2026/05/Water-molecules-found.png?resize=1200%2C720&ssl=1)
Researchers have uncovered a previously hidden layer of complexity in how genes are activated, showing that water molecules play a direct and essential role in one of the most fundamental […]
cryo-electron microscopy
Posted inGenomics, Proteomics, Bioinformatics, Imaging & Spectroscopy, Intelligence & Language, Press Release
The Calcium Sensor Helps Humans And Other Earth Life See The Stars
Using cryo-electron microscopy and mass spectrometry, researchers from PSI have deciphered the structure of an ion channel found in the eye while it interacts with the protein calmodulin – a […]