Aminotransferases Archives

Poor conservation of AT groups across the ToL due to wide-spread replacement of ATs from distantly related non-orthologous AT groups. (A) Percent conservations (with red to yellow background colors) of 62 AT and related groups for different taxonomic groups and ranks. (B) AT and related groups were clustered based on the similarity of gene copy numbers within each species. Species were arranged based on the taxonomic relationship at the top: Gray, brown, orange, red, green and blue depict archaea, protists, fungi, animals, plants, and eubacteria, respectively. Species marked with a star (*) contain secondary plastids. Brown filled boxes indicate that certain enzymes (left) are present in the corresponding species (top). Magenta open boxes highlight 11 clusters (CTs) which are labeled at the corresponding branches of the clustering tree. -- biorxiv.org

Multi-substrate Specificity Shaped The Complex Evolution Of The Aminotransferase Family Across The Tree Of Life

by Keith CowingMarch 24, 2024

Aminotransferases (ATs) are an ancient enzyme family that play central roles in core nitrogen metabolism essential to all organisms. However, many of the AT enzyme functions remain poorly defined, limiting […]

Aminotransferases

Multi-substrate Specificity Shaped The Complex Evolution Of The Aminotransferase Family Across The Tree Of Life

Material Cycling Across Earth’s Spheres And Triggers Of Cambrian Explosion: A Tectonic Perspective

Where Does Earth’s Nitrogen Go? Two Atoms Offer A Clue

Exotic Methanol Discovered In Planet-Building Zones

More Than One Thousand TESS Planets

First Detection Of Variable Water Clouds Outside Of Our Solar System