β-sheets Archives

Design and evaluation of random peptide libraries using distinct amino acid alphabets. (a) Chemical structures of 16 α-amino acids assembled through solid phase peptide synthesis to generate random 25-mer peptides utilising one of nine distinct alphabets (collections of amino acids). Dap, 2,3-diaminopropionic acid; Dab, 2,4-diaminobutyric acid; Aad, 2- aminoadipic acid; Api, 2-aminopimelic acid. -- biorxiv.org

Biochemistry & Organic Chemistry, Biophysics, Biosignatures & Paleobiology, Genomics, Proteomics, Bioinformatics, Origin & Evolution of Life, Status Report

Prebiotically Plausible Peptides Can Self-assemble Into β-rich Nanostructures

by Keith CowingNovember 17, 2025November 17, 2025

Modern proteins are remarkable polymers built from a 20-amino-acid alphabet, shaped by billions of years of evolution. Yet in Earth’s prebiotic era, several amino acids – particularly the canonical basic […]

β-sheets

Prebiotically Plausible Peptides Can Self-assemble Into β-rich Nanostructures

NASA Establishes Mars Forward Operational Risk and Contamination Evaluation (M-FORCE) Tiger Team to Shape Mars Planetary Protection Protocols

Opportunity to Contribute to NASA DARES Community White Paper on Phototrophic Biosignatures

The Search For Life Elsewhere: Avoiding Hype and Fostering Public Understanding

Panchromatic Spectra of Nearby Low-mass and Sun-like Stars with Directly Imageable Habitable Zones

Alfred: A Flexible, User-Friendly Python Package for Exoplanet Confirmation