The emergence of biomolecular homochirality requires both an initial symmetry-breaking event and a mechanism to amplify and preserve a chiral imbalance.
prebiotic chemistry
Liquid–liquid Phase Separation As A Driver Of Abiogenesis And Evolution
The origin of life may have emerged through physical mechanisms that enable molecular organization and self-assembly. Building on Alexander Oparin’s concept of coacervate droplets, liquid–liquid phase separation (LLPS) offers a […]
Analytical Characterization Approaches to Measure Prebiotically Relevant Compounds in High Salinity Impact-Induced Hydrothermal Systems
Experiments exploring potential emergence-of-life chemistry in a laboratory setting critically depend on simulating realistic early-Earth environments. Such experimental conditions include the implementation of controlled high temperatures and pressures, anoxic gas […]
Novel Chemical Pathways For The Formation Of Nucleobase Precursors Via Benzene π-Bond Addition To HCN
We propose a simple and efficient pathway for the formation of precursors to core nucleobases in DNA and RNA using a suite of computational chemistry methods.
A Clue For The Hen And Egg Question: The Simultaneous Formation Of Uracil And Amino Acids Under Simulated Hadean Conditions
The origin of life is commonly discussed within two competing conceptual frameworks: the metabolism-first and information-first hypotheses. While each emphasizes a different defining property of early life, modern biochemistry reveals […]
Shedding Light On How Hydrogen Cyanide Formed On Early Earth
Manganese dioxide can convert amino acids into hydrogen cyanide (HCN) without requiring methane, solving a long-standing puzzle about the origin of this key prebiotic molecule on early Earth, as reported […]
Showing The Math For Earth’s First — And Sudden — Spark Of Life
Isolating the first spark of life on Earth is a matter of biology, geology, and chemistry — but it’s also an amazing math problem. At least, that’s how Varun Varanasi […]
Flare-driven Habitability: Expanding Life’s Potential Around Low-mass Stars
The traditional definition of the circumstellar habitable zone (HZ) focuses on liquid water, but neglects the crucial role of ultraviolet (UV) radiation in prebiotic chemistry.
Science Goals and Objectives for the Dragonfly Titan Rotorcraft Relocatable Lander
NASA’s Dragonfly mission will send a rotorcraft lander to the surface of Titan in the mid-2030s. Dragonfly’s science themes include investigation of Titan’s prebiotic chemistry, habitability, and potential chemical biosignatures […]
Prebiotic Chemistry Insights for Dragonfly II: Thermodynamic Favorability of Nucleobases, Ribose, and Fatty Acids in Selk Crater on Titan
Saturn’s moon Titan is a prime destination for investigating prebiotic chemistry beyond Earth, particularly at impact crater sites where transient liquid water may have enabled aqueous reactions between organic molecules.
