European Bioinformatics Institute Archives

Slime mould Dictyostelium discoideum protein complex Q55DI5 (AF-0000000066503175), annotated as a transcription elongation factor. The single chain looked disordered, but modelling the homodimer revealed that two chains intertwine, each contributing half a domain to form a stable fold. An illustration of why predicting protein complexes can reveal biology that single-protein models miss. Credit AlphaFold Database, background by Karen Arnott/ EMBL-EBI

Astropharmacy / Biotechnology, Biochemistry & Organic Chemistry, Biophysics, Biosignatures & Paleobiology, Genomics, Proteomics, Bioinformatics, Nanotechnology & SynBio, Press Release

Millions Of Protein Complexes Added To AlphaFold Database Shed Light On How Proteins Interact

by Keith CowingMarch 18, 2026March 18, 2026

A new collaboration between EMBL’s European Bioinformatics Institute (EMBL-EBI), Google DeepMind, NVIDIA, and Seoul National University has made millions of AI-predicted protein complex structures openly available through the AlphaFold Database. […]