The abstract in PubMed or at the publisher’s site is linked when available and will open in a new window.
Papers deriving from NASA support:
- Piekarski DJ, Guarnieri J, Arif S, Aslinger E, McNerney MW.Spaceflight modulates neurodegeneration-associated transcriptomic pathways across brain cell types.Life Sci Space Res. 2026 Aug 27. Online ahead of print.Note: ISS results. GeneLab is available at https://genelab.nasa.gov.
Journal Impact Factor: 3.3
Acknowledgments: “The authors thank the NASA Biological and Physical Sciences (BPS) Division for supporting the NASA Ames Life Sciences Data Archive (ALSDA), NASA GeneLab, and their umbrella project, the NASA Open Science Data Repository (OSDR), which are valuable national and global resources for the future of space biology and space health. We thank the OSDR team and the GeneLab Sample Processing Lab for producing, curating, and processing the single-nucleus RNA-sequencing data from the Rodent Research …” - Aravindan N, Manickam K, Adhikary A, Natarajan M.Space radiation sparks hidden cancer risks: The bystander effect unveiled.Space Sci Technol. 2026 Jun 18;6:0518.PI: M. NatarajanNote: This article may be obtained online without charge.
Journal Impact Factor: 6.4
Funding: “This work was supported by the NASA Ground-Based Studies in Space Radiobiology (grant NNX12AC32G), National Space Biomedical Research Institute grant CA02802 through NASA (NCC 9-58-298), National Institutes of Health/National Institute of Diabetes and Digestive and Kidney Diseases grant(5 RO1 DK096119), Department of Defense (CA-210339), Oklahoma Canter for the Advancement of Science and Technology (OCAST-HR19-045), and National Institutes of Health National Institute of General Medical Sciences (P20GM103639).” - Krull NK, Strobel M, Saulog J, Zaroubi L, Paulo BS, Timba M, Braun DR, Mingolelli G, Raherisoanjato J, Shepherd RA, Scott AF, De Silva C, Fergusson C, Daniel Z, Pokharel SK, Romanowski S, Hernandez A, Monge-Loría M, Dylla CE, Natu MM, Petukhova VZ, Clark CM, Garg N, Jensen PR, Blachowicz A, Cassilly CD, Guan L, Stevens DC, Winter JM, McKinnie SMK, Adaikpoh BI, Carlson S, McCauley EP, Metcalf WW, Bugni TS, Mullowney MW, Pamer EG, Henke MT, Barton H, Carter DO, Eustáquio AS, Linington RG, Sanchez LM, Wang M, Murphy BT.IDBac: An open-access web platform to identify bacteria and analyze relationships in culture collections using MALDI-TOF mass spectrometry.Nat Commun. 2026 Jul 23;17(1):8956.PI: PI NAMESNote: This article may be obtained online without charge.
Journal Impact Factor: 18.1
Funding: A. Blachowicz and L. Guan are affiliated with NASA Jet Propulsion Laboratory. C.D. Cassilly is affiliated with NASA Marshall Space Flight Center. - Xu Y, Jarrah S, Zhang S, Khlgatian MK, Brojakowska A, Du Y, Eskandari A, D’Escamard V, Kovacic JC, Goukassian DA.Space radiation impairs long-term endothelial integrity and may promote atherosclerosis in ApoE-deficient mice.Clin Transl Med. 2026 Aug 13;16(8):e70774.PI: D.A. GoukassianNote: This article is a Letter to the Journal and may be obtained online without charge.
Journal Impact Factor: 7.9
Funding: “… David A. Goukassian is supported by the National Aeronautics and Space Administration Human Research Program, grant No: 80NSSC19K1079 (formerly, 80NSSC18K0921).” - Yarbrough D, Chen R, Katsouleas K, Shoemaker J, Brady T, Yu T, Arthur Ataam J, Amelung C, Santhanam L, Karakikes I, Gerecht S.Artery-on-chip demonstrates mechanical and functional features of healthy and diseased living smooth muscle tissue.Adv Funct Mater. 2026 Jul 1;36(59):e76324.PI: S. GerechtNote: This article may be obtained online without charge.
Journal Impact Factor: 19.9
Funding: “… We acknowledge support from the Duke Cancer Institute as part of the P30 Cancer Center Support Grant (Grant ID: P30 CA014236). This work was supported by RAD0102 and SNT0101 from the Translational Research Institute through NASA Cooperative Agreement NNX16AO69A (both to S.G.), and grants from National Institutes of Health (R01 HL139679 and R01 HL150414) and the Leducq Foundation (both to I. K.).”
Other papers of interest:
- Caicedo A, Villarroel A, Rendón C, Rodríguez-Arias E, Salgado D, Andrade P, Andrango F, Pacheco P, Castañeda V, Maya R, Haro-Vinueza A, Villavicencio D, Pazmiño-Zurita G, Benavides-Almeida A, Pérez-Meza ÁA, Arizo P, Chile-Miranda S, Mitra K, Beheshti A.Extracellular mitochondrial DNA and extracellular mitochondria as biomarkers of spaceflight stress: Implications for safeguarding astronaut health.npj Microgravity. 2026 Aug 14. Early access article.Note: This article may be obtained online without charge.
- Cassaro A, D’Alò F, Díaz-Rullo J, Pacelli C, Zucconi L, González-Pastor JE, Onofri S.Transcriptomic insights into the mild dehydration response of Cryomyces antarcticus: Cell cycle arrest, amino acid biosynthesis, and ion homeostasis as survival strategies in arid environments.Life Sci Space Res. 2026 Aug 21. Online ahead of print.Note: From the abstract: “Water is essential for life, and dehydration can cause severe damage to cellular components such as proteins, nucleic acids, and membrane lipids, unless appropriate protective mechanisms are activated to counteract its effects. Several organisms have evolved survival strategies that allow them to endure extreme water loss by entering an ametabolic state known as anhydrobiosis. However, the effects of dehydration on microbial functions and the underlying survival mechanisms remain poorly understood. Here, we report a comprehensive transcriptional analysis of the black fungus Cryomyces antarcticus, isolated from sandstones in the McMurdo Dry Valleys (Southern Victoria Land, Antarctica), in response to mild dehydration treatment.”
- Géczy G, Seres I.Operational astronaut and payload radiation exposure during the Axiom-4 spaceflight measured by RadNano Infinity Astronaut Dosimeters.Sci Rep. 2026 Aug 13. Early access article.Note: This article may be obtained online without charge.
- Huang C-W, Baiocco G, Kundrát P.Comprehensive database of track-structure simulations on DNA damage by H-Fe ions up to 1 GeV/u for space radiation biology.Sci Rep. 2026 Jun 9;16:26153.Note: This article may be obtained online without charge.
- Kern C, Cook M, Reynolds E, Ashar A, Siew K, Johnson IRD, Grzesiak N, Jopling L, Christian M, Libera R, Gartner I, Ferreira MJS, Salem AK, Birch W, Dhanji N, Cullen DC, Sampaio JM, Oliveira D, Catchpole S, Richardson R, Milašius D, Bailey DM.Space biology as a catalyst for the next biotech and longevity revolution.Exp Physiol. 2026 Aug 18. Online ahead of print.Note: This article may be obtained online without charge.
- Ji G, Zhou Z, Xia H, Zhao Z, Lu H.Simulated microgravity induces HIF-1-mediated metabolic reprogramming in triple-negative breast cancer cells.npj Microgravity. 2026 Aug 19. Early access article.Note: A random positioning machine was used in this study to simulate microgravity. This article may be obtained online without charge.
- Luo L, Wu J, Du S.Stochastic dynamics of multistep colorectal carcinogenesis under deep-space radiation and microgravity: A large-deviation and quasipotential framework.Life Sci Space Res. 2026 Aug 25. Review. Online ahead of print.
- Otsuki A, Aoki Y, Okada R, Baird L, Kamimura D, Shiba D, Hishinuma E, Koshiba S, Katsuoka F, Kinoshita K, Suzuki T, Uruno A, Yamamoto M.ibSLS as a biobank for democratizing access to multi-omics data and biospecimens from spaceflight research.Nat Commun. 2026 Aug 20;17.Note: From the abstract: “During spaceflight, astronauts are exposed to extreme conditions such as microgravity, cosmic radiation, and confinement, which can cause a wide range of health problems. To elucidate the molecular mechanisms underlying these issues and to develop intervention strategies for maintaining physiological homeostasis during space missions, space life science research using mouse models is actively conducted on the International Space Station (ISS). However, because of the high cost and technical complexity of spaceflight experiments, it is essential to maximize the scientific value of each mission by ensuring broad accessibility to both data and biospecimens. To this end, we present the integrated biobank for Space Life Science (ibSLS; https://ibsls.megabank.tohoku.ac.jp, a data-visualization and sample-sharing platform that provides access to transcriptomic and metabolomic datasets generated from Mouse Habitat Unit (MHU) missions conducted by the Japan Aerospace Exploration Agency (JAXA).” This article may be obtained online without charge.
- Quinto LF, Atento RG, Dela Cruz W, Morcilla J, Castañeda CO.Mitochondrial dysfunction as a convergent mechanism in spaceflight-associated pathology: Implications for countermeasure development.Frontier Science and Futures. 2026 Jul 31;1(1).Note: This article may be obtained online without charge.
- Sappa S, Keremane P, Mumbrekar KD.Microgravity-induced gut dysbiosis and its consequences for brain health.Microgravity Sci Technol. 2026 Aug 1;38(4):50. Review.Note: This article may be obtained online without charge.
- Shen Y, Shi H, Meng F, Qi R.A comprehensive review of humidity management in crewed spacecraft: Standards, technological advances and applications.Renew Sustain Energy Rev. 2026 Jul;234:116864.
- Wang H, Xue S, Zhang H, Dai F, Chen S, Wang C, Fu Y.Shared mental astronaut-robot team: How astronauts and autonomous robots establish fault recovery experimental platform during crewed space missions.Int J Hum.-Comput Interact. 2026 Mar 10:1-24.
- Wang W, Li T, Wu H, Wu H, Cui Y, Deng H, Xiang W, Li C.Polysaccharide accumulation and antioxidant activity in space-mutated Spirulina platensis H11 under seawater versus freshwater cultivation.Mar Drugs. 2026 Aug 5;24(8):272.Note: This article may be obtained online without charge.
- Beauchamps V, Sauvet F, Boyer S, Nemmi F, Buratto F.Evaluate the effectiveness of cognitive stimulation and physiological dynamization on sleep inertia.Front Physiol. 2026 Aug 24;17:1855408.Note: This article may be obtained online without charge.
- Bergauer A, Urevc J, Steuber B, Schmid-Zalaudek K, Pivec V, Goswami N.Dose-dependent reduction of optic nerve sheath diameter during graded lower body negative pressure in healthy adults of both sexes.Front Netw Physiol. 2026 Aug 6;6:1908460.Note: This article is part of Research Topic “Network Physiology in Space: Exploring Physiological Networks during Space Flight for the Benefit of Life on Earth” (https://www.frontiersin.org/research-topics/75817/network-physiology-in-space-exploring-physiological-networks-during-space-flight-for-the-benefit-of-life-on-earth). The Research Topic includes articles from previous Current Awareness Lists #1198 https://doi.org/10.3389/fnetp.2026.1817815 and https://doi.org/10.3389/fnetp.2026.1867627. Additional articles will be forthcoming and may be found in the link to the Research Topic. This article may be obtained online without charge.
- Chen D, Ma L, Chen J, Zhang X, Hou X, Yang M, Wang Y, Lei X, Duan X, Feng Y, Wilkinson S.Biophilic design in closed cabins: A scoping review of habitability countermeasure pathways under isolated, confined, and extreme conditions.Acta Astronaut. 2026 Dec;249(Part B):228-52.
- de la Torre GG, Ramallo-Luna MA, López-Ramírez JA, Gonzalez-Torre S, García-Villadangos M, Carrasco Gómez M, Zarandona Palacio PJ, Claeys K, Avila-Rauch C, Mintus A, Ceballos D, Violadé C, Ráčková L.Cognitive performance and psychological wellbeing in hybrid human-robot crews in space analog missions: The delayed unwinding paradox.Acta Astronaut. 2026 Aug 24. Online ahead of print.Note: This article may be obtained online without charge.
- Farkas SZ, Grippo F, Oulehlová D, González-Delgado A, Noura S, Molazeinali S, Wabnik K, Fendrych M, Waidmann S, Kleine-Vehn J.SHOOT GRAVITROPISM 9 links sensory timing to the initial lateral root growth angle.Proc Natl Acad Sci USA. 2026 Jul 22;123(30):e2536276123.Note: This article may be obtained online without charge.
- Cui Z, Xie T, Zhou Y, Gong P, Zhang X, Wang P.Exploring the differences in neural oscillation mechanisms before and after sleep deprivation.Front Neurosci. 2026 Aug 2;20:1910878.Note: This article may be obtained online without charge.
- Shankhwar V, Garg R, Deepak KK, Singh D.Multimodal coherence mapping of cardiac, vascular, and respiratory dynamics during 6° head-down tilt.Life Sci Space Res. 2026 Aug 26. Online ahead of print.
astrobiology, Microgravity, NASA, space biology, space medicine, spaceline,
