NASA Spaceline Current Awareness List #1,210 31 July 2026 (Space Life Science Research Results)

The abstract in PubMed or at the publisher’s site is linked when available and will open in a new window.

Papers deriving from NASA support:

Neset M, Mielkozorova M, Patron M, Hazra S, Unnithan VB, Girma SM, France H, Singh R, Ly V, Majid MY, Campbell JE, Rosasco R, Grove K, Morris M, Narayanan SA, Scott RT, Komarova SV.A systematic mapping review of studies reporting the effects of spaceflight on cardiovascular outcomes.Life Sci Space Res. 2026 Sep;52:37-44. Review.PI: S.A. NarayananNote: This article may be obtained online without charge.

Journal Impact Factor: 3.3

Funding: PI reports NASA grant #80NSSC23K0885 funding.
Rahman B, Saroyia AP, Blackburn D, Parish AJ, Szewczyk N, Driscoll M, Samuel BS, Vanapalli SA.NemaCapsules: Microfluidics-integrated biocells for investigating C. elegans host-microbiome interactions in spaceflight.npj Microgravity. 2026 Jul 23. Early access article.PI: S.A. VanapalliNote: This article may be obtained online without charge.

Journal Impact Factor: 5.1

Funding: “We gratefully acknowledge NASA for their financial support for this research (project# 80NSSC22K0250) and BioServe Space Technologies ® for providing biocell hardware and the integration protocol to form NemaCapsules, in addition to their 3-D hardware schematics for figures.”
Dicker ML, Consiglio AN, Weng Y, Reyna JC, Ametepe BAAB, Tong T-T, Rubinsky B, Chang TT.Isochoric supercooling improves preservation of hepatic spheroid viability and structure compared to 4°C cold storage.Cryobiology. 2026 Sep;124:105680.PI: T.T. ChangNote: From the abstract: “In this report, we investigated the preservation of self-assembled HepG2 hepatic cell line spheroids in isochoric -6°C supercooling conditions compared to 4°C cold storage.”

Journal Impact Factor: 2.6

Funding: “This work was supported by the Translational Research Institute for Space Health (TRISH) through NASA Cooperative Agreement [grant number NNX16AO69A], National Science Foundation (NSF) [award numbers 1830768 and 2234490], and NSF Engineering Research Center for Advanced Technologies for Preservation of Biological Systems (ATP-Bio) [EEC #1941543].”
Fu Y, Li X, rahmani s, Chen C, Du D, Van Dongen HPA, Qiu K, Lin Y.Flexible electrochemical sensors: Emerging biomedical applications and future perspectives.ECS Sensors Plus. 2026 Jul 21. Early access article.Note: From the abstract: “This review provides a comprehensive overview of recent advances in flexible electrochemical sensors, with particular emphasis on nanomaterial engineering, device fabrication strategies, and biomedical applications.” This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: “This work was supported by NASA grant 80NSSC25M7148 and NIOSH grant R01OH012579.”
Kumar A, Patel R, Johnson D, Jain A.IncuSense: IoT-enabled wireless long-term multiparametric cell culture incubator monitoring system.Ann Biomed Eng. 2026 Jul 16.PI: A. JainNote: This article may be obtained online without charge.

Journal Impact Factor: 5.2

Funding: “This material is based upon work supported by the US Army Medical Research (USAMRAA) Contract No. HT94252410432; NASA, BARDA, NIH, and USFDA, under Contract No. 80ARC023CA002; NHLBI of NIH under Award Number R01HL157790; TAMU Office of Innovation Translational Investment Funds; and National Institute of Dental and Craniofacial Research (Grant No. R21DE035321) to A.J.”
Robin A, Reinarz CD, Pentinat-Llurba H, Zaman SY, Rasmussen CJ, McKnight JR, Haddad L, Zawieja DC, Diaz-Artiles A.Dose-dependent effects of graded altered gravity during hypovolaemia on central haemodynamics and cardiovascular autonomic regulation.Exp Physiol. 2026 Jun 19. Online ahead of print.PI: A. RobinNote: From the abstract: “The cardiovascular system is strongly influenced by gravitational loading and blood volume status. Quantifying central haemodynamic and autonomic reflex responses to fluid redistribution is important in altered-gravity conditions, with relevance to spaceflight and clinical medicine. However, the continuous physiological response to graded gravitational loading under hypovolaemia has not been characterized. Here, we used graded tilt to derive continuous dose-response relationships to altered gravity during acute hypovolaemia.” This article may be obtained online without charge.

Journal Impact Factor: 3.0

Funding: “Funding information This work was supported by the Translational Research Institute for Space Health through NASA Cooperative Agreement NNX16AO69A.”
Voropayev V, Marques M, Maleki A, Lyrintzis AS, Mankbadi RR, Grace S, Golubev VV.High-fidelity simulations of noise induced by time-harmonic gust interaction with eVTOL rotor.Int J Aeroacoustics. 2026 Jun;25(3-4):381-406.Note: This article may be obtained online without charge.

Journal Impact Factor: 1.1

Funding: “This research is based upon work supported by the NASA Aeronautics Research Mission Directorate (ARMD) University Leadership Initiative (ULI) under cooperative agreement number 80NSSC21M0057. Anyopinions, findings, and conclusions or recommendations expressed in this material are those of the authors and do not necessarily reflect the views of the National Aeronautics and Space Ad ministration. Resources supporting this work were provided by the NASA High-End Computing (HEC) Program through the NASA Advanced Supercomputing (NAS) Division at Ames Research Center.”
Wozniak KJ, Pan L, Zhu D, Corver J, Kuijper EJ, Smits WK, Britton RA.Acquisition of a gene cluster in Clostridioides difficile PCR ribotype 023 strains enables xylitol utilization.mSphere. 2026 Jul 16;e0026326. Online ahead of print.PI: K.J. WozniakNote: This article may be obtained online without charge.

Journal Impact Factor: 4.0

Funding: “This work was supported by U19AI157981 and R01AI123278 to R.A.B. K.J.W. was supported by the Translational Research Institute for Space Health through Cooperative Agreement NNX16AO69A and a training fellowship from the Gulf Coast Consortia, on the Antimicrobial Resistance Training Program in the Texas Medical Center (AMR-TPT) (NIAID Grant no. T32AI179595).”
Yarbrough D, Chen R, Katsouleas K, Shoemaker J, Brady T, Yu T, Arthur Ataam J, Amelung C, Santhanam L, Karakikes I, Gerecht S.Artery-on-chip demonstrates mechanical and functional features of healthy and diseased living smooth muscle tissue.Adv Funct Mater. 2026 Jul 1;e76324. Online ahead of print.PI: S. GerechtNote: This article may be obtained online without charge.

Journal Impact Factor: 19.9

Funding: “We acknowledge support from the Duke Cancer Institute as part of theP30 Cancer Center Support Grant (Grant ID: P30 CA014236). This work was supported by RAD0102 and SNT0101 from the Translational Research Institute through NASA Cooperative Agreement NNX16AO69A (both to S.G.), and grants from National Institutes of Health (R01 HL139679 and R01 HL150414) and the Leducq Foundation (both to I. K.).”

Other papers of interest:

Naco CSA, Quiming NS, Octavo CJM, Lim CCYY, Obico JJA, Bonto AP, Sumayao RE, Tan MCS, Ajero MDM, Alcantara BJ, Tan AA, Taaca KLM, Vasquez MR, Nuñez JAP.Space-flown spearmint (Mentha spicata L.) seeds potentially tolerate nitro-oxidative stress from plasma-activated water.Front Plant Sci. 2026 Jul 28;17:1836606.Note: ISS results. This article may be obtained online without charge.
Marza L, Mohammed R, Abdelrahman Y, Hajjiri A, Abuhjar M, Deen GR.Unravelling the impact of microgravity on calcium ion signaling and sensorium in spaceflight.Life (Basel). 2026 Jun 30;16(7):1096. Review.Note: This article is part of Section “Physiology and Pathology” (https://www.mdpi.com/journal/life/sections/Physiology_and_Pathology) and may be obtained online without charge.
Oliveira ME, Pereira P, Oliveira ES.Defining surgical capability in spaceflight: A scoping review of feasibility, technologies, and operational constraints.Acta Astronaut. 2026 Jul 24. Online ahead of print.Note: This article may be obtained online without charge.
Gao H, Yin Y, Ye G, Peng Y, Ding Z, Zhang Y, Lu W.Engineering food systems for microbiome stability and metabolic health in deep-space missions.Trends Food Sci Technol. 2026 Sep;175:105875.
Martella CM, Di Stefano G, Chirico A, D’Agostino A, D’Andrea MM, Colini F, Iacovelli F, Falconi M, Verna A, Scifo J, Cemmi A, Billi D.Harnessing desiccation-tolerant cyanobacteria as biosensors for LexA-mediated responses in deep space.Front Microbiol. 2026 Jul 14;17:1842062.Note: This article is part of Research Topic “Microorganisms as Astro-pioneers for Long-term Sustainable Human Presence in Space” (https://www.frontiersin.org/research-topics/70040/microorganisms-as-astro-pioneers-for-long-term-sustainable-human-presence-in-space). The Research Topic also includes articles from previous Current Awareness List #1,173 https://doi.org/10.3389/frspt.2025.1651978. This article may be obtained online without charge.
Sung D.Decision-making in aerospace medicine research, development, and regulation: A philosophical primer.KJAsEM. 2026 Jun 11;36(2):34-40. Review. Korean.
Yazdanpanah F, Y., Asmarz H.From Earth to orbit: Cardiovascular innovation diffusion to space medicine – an updated review incorporating a novel predictive modeling framework.Front Physiol. 2026 Jul 27;17:1890835.Note: This article may be obtained online without charge.
Zanon C, Basilicata M, Chiaravalloti A, Giannotti N, Lupi A, Crimì F, Quaia E.Space radiation and cancer risk in astronauts: Models, evidence, uncertainties, and emerging imaging perspectives.Tomography. 2026 Jul 17;12(7):106.Note: This article is part of Section “Cancer Imaging” (https://www.mdpi.com/journal/tomography/sections/cancer_imaging) and may be obtained online without charge.
Bechet R, Schepens B, Gambelli CN.Mechanical demand shapes anticipatory kinematic adjustments differently in drop and jump landings: Evidence from a microgravity paradigm.J Biomech. 2026 Aug;205:113469.Note: From the abstract: “Landing from a jump presents distinct challenges that require accurate prediction of both ground contact timing and the characteristics of the forthcoming impact forces to generate anticipatory kinematic adjustments to efficiently dissipate energy. This study quantified these adjustments under simulated microgravity to characterize their temporal and magnitude features. Nine participants performed countermovement jumps (CMJ) and drop-landings (DL) under simulated microgravity during parabolic flights, using a subject loading system to apply downward force in weightlessness (0g).” This article may be obtained online without charge.
Zhang H, Li B, Zou Y, Yao F, Su W, Li B.From collapse to active self-repair: Integrative multi-omics and machine learning analysis map the hepatic metabolic adaption in response to simulated spaceflight stress.Faseb j. 2026 Jul 30;40(15):e72165.Note: From the abstract: “Long-term spaceflight poses substantial challenges to human physiology, with the liver being highly susceptible due to its central metabolic role. To determine whether hepatic alterations represent transient stress or sustained remodeling, we performed an integrated multi-omics analysis in a rat model simulating chronic space radiation and microgravity. Herein, we applied an integrated multi-omics and AI-driven analytical framework combining histopathology, cytokine and miRNA profiling, proteomics, metabolomics and Western blot validation.” GeneLab is available at https://genelab.nasa.gov.
Miyake K, Ogawa Y, Kato T, Sugimura K, Iwasaki KI.Sex differences in changes in cerebral blood flow induced by short-term mild +Gz hypergravity in young males and females.J Appl Physiol (1985). 2026 Jul 24. Online ahead of print.Note: This article may be obtained online without charge.