NASA Spaceline Current Awareness List #1,119 11 October 2024 (Space Life Science Research Results)

The abstract in PubMed or at the publisher’s site is linked when available and will open in a new window.

Papers deriving from NASA support:

1. Corti G, Kim J, Enguita FJ, Guarnieri JW, Grossman LI, Costes SV, Fuentealba M, Scott RT, Magrini A, Sanders LM, Singh K, Sen CK, Juran CM, Paul AM, Furman D, Calleja-Agius J, Mason CE, Galeano D, Bottini M, Beheshti A.To boldly go where no microRNAs have gone before: Spaceflight impact on risk for small-for-gestational-age infants.SOURCE.PI: C.E. MasonNote: GeneLab is available at https://genelab.nasa.gov. This article may be obtained online without charge.
   
   Journal Impact Factor: 5.2
   
   Funding: “Part of the work was performed under funding from NASA’s Biological and Physical Sciences Division to NASA Ames under the Task: ID016GLS, Contract Number: NNA14AB82C awarded to A.B. C.E.M. thanks the Scientific Computing Unit (SCU) at WCM, the WorldQuant and GI Research Foundation, NASA (NNX14AH50G, NNX17AB26G, NNH18ZTT001N-FG2, 80NSSC22K0254, 80NSSC23K0832, the National Institutes of Health (R01ES032638, U54AG089334), and the LLS (7029-23). J.K. was supported by Basic Science Research Program through the National Research Foundation of Korea(NRF), funded by the Ministry of Education(RS-2023-00241586). C.E.M and J.K. acknowledges Boryung for their financial support and research enhancement ground, provided through their Global Space Healthcare Initiative, Humans In Space, including mentorship and access to relevant expert networks.”
2. Tasoula A, Szewczyk N.Astronaut proteomics: Japan leads the way for transformative studies in space.Proteomics. 2024 Oct 10;24(20):e2300645.Note: This article is a commentary.
   
   Journal Impact Factor: 3.4
   
   Funding: “Osteopathic Heritage Foundation; NSSC22K0250/NASA/NASA/United States; NSSC22K0278/NASA/NASA/United States.”
3. Kumar S, Suman S, Angdisen J, Moon B-H, Kallakury BVS, Datta K, Fornace AJ Jr.Effects of high-linear-energy-transfer heavy ion radiation on intestinal stem cells: Implications for gut health and tumorigenesis.Cancers. 2024 Oct 4;16(19):3392.PI: A.J. Fornace JrNote: This article is part of Special Issue “Radiation Exposure, Inflammation and Cancers” (https://www.mdpi.com/journal/cancers/special_issues/33Q81IUBU9). Additional articles will be forthcoming and may be found in the link to the Special Issue. This article may be obtained online without charge.
   
   Journal Impact Factor: 4.5
   
   Funding: “This study was supported in part by National Aeronautics and Space Administration (NASA) Grant Numbers 80NSSC22K1279 and NNX15AI21G.”
4. Walsh K.The emergence of clonal hematopoiesis as a disease determinant.J Clin Invest. 2024 Oct 1;134(19). Review.PI: K. WalshNote: This article may be obtained online without charge.
   
   Journal Impact Factor: 13.3
   
   Funding: “KW is supported by NIH grants AG073249 and AG086508 and NASA grant 80NSSC21K0549.”
5. Curry A, Spern CJ, Khodadad CLM, Hummerick ME, Spencer LE, Torres J, Finn JR, Gooden JL, Monje O.Post-harvest cleaning, sanitization, and microbial monitoring of soilless nutrient delivery systems for sustainable space crop production.Front Plant Sci. 2024 Oct 11;15:1308150.Note: This article is part of Research Topic “Progressing the Future of Space Agriculture” (https://www.frontiersin.org/research-topics/52433/progressing-the-future-of-space-agriculture#overview). The Research Topic also includes articles from previous Current Awareness Lists #1,055 https://doi.org/10.3389/fpls.2023.1194753, #1,069 https://doi.org/10.3389/fpls.2023.1265458, #1,070 https://doi.org/10.3389/fpls.2023.1266199, #1,079 https://doi.org/10.3389/fpls.2023.1284529, #1,085 https://doi.org/10.3389/fpls.2023.1289208, and #1,089 https://doi.org/10.3389/fpls.2024.1351613. This article may be obtained online without charge.
   
   Journal Impact Factor: 4.1
   
   Funding: “The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This work was supported by a National Aeronautics and Space Administration (NASA) Grant entitled ‘Evaluation of the Porous Tube and On-Demand Water and Nutrient Delivery Systems for Food Production in Microgravity’-80NSSC20K1834 awarded to OM.”

Other papers of interest:

1. Di Filippo ES, Chiappalupi S, Falone S, Dolo V, Amicarelli F, Marchianò S, Carino A, Mascetti G, Valentini G, Piccirillo S, Balsamo M, Vukich M, Fiorucci S, Sorci G, Fulle S.The MyoGravity project to study real microgravity effects on human muscle precursor cells and tissue.npj Microgravity. 2024 Oct 3;10:92.Note: ISS results. This article may be obtained online without charge.
2. Chang HHV, Kim KS.Review on the impact of spaceflight stressors on the vestibular system: Beyond microgravity to space radiation.Res Vestib Sci. 2024 Sep 15;23(3):71-8. Review.Note: This article may be obtained online without charge.
3. Jayakumar D, Pachiyappan JK, Roychowdhury P, Kuppusamy G, Mr J, Karri VVSR, Venkatesan J, Mallick S, Tagde P, Shaikh NK, Khan FS.The impact of cardiovascular deconditioning in space: A review.Acta Astronaut. 2024 Oct 10. Online ahead of print.
4. Oommen AM, Stafford P, Joshi L.Profiling muscle transcriptome in mice exposed to microgravity using gene set enrichment analysis.npj Microgravity. 2024 Oct 4;10:94.Note: GeneLab is available at (https://genelab.nasa.gov). This article may be obtained online without charge.
5. Pagnini F.Supporting the mind in space: Psychological tools for long-duration missions.Interact J Med Res. 2024 Sep 10;13:e66626.Note: This article is a commentary and may be obtained online without charge.
6. Pattyn N, Charlesworth S, Manzey D.Mental performance in extreme environments (space and Antarctica).In: Handbook of Mental Performance. London: Routledge, 2024. p. 296-315.Note: This book chapter may be obtained online without charge.
7. Smith L.Automated psychotherapy in a spaceflight environment: Advantages, drawbacks, and unknowns.Interact J Med Res. 2024 Sep 10;13:e58803.Note: This article may be obtained online without charge.
8. Gonzalez-Torre S, Rasero A, Diaz-Artiles A, Ramallo MA, de la Torre GG.Latent personality profiles of analog astronauts: An unsupervised clustering method analysis.Acta Astronaut. 2024 Oct 5. Online ahead of print.Note: From the abstract: “The selection of astronauts for space missions is an important process that involves the assessment of multiple factors, including personality traits. Previous studies have corroborated that these traits exert a significant influence on the performance and adaptation of the crew during the execution of space missions. In this study, International Personality Item Pool – NEO – 120 (IPIP-120) was used to assess the personality of participants in a sample of 43 analog astronauts who took part in 9 different analog missions between 2022 and 2023.”
9. Ding Z, Wang D, Zhang S, Yang X, Xu M, Li W, Shi Q, Gao B, Wang Y, Yan M.Role and mechanism of histone demethylase PHF8 in weightlessness osteoporosis.Exp Cell Res. 2024 Oct 9;114270.Note: From the abstract: “Weightlessness osteoporosis, which progresses continuously and has limited protective effects, has become one of the major problems that need to be solved in crewed spaceflight. Our study aims to investigate the regulatory role of PHF8 in disuse osteoporosis by observing the expression of PHF8 in bone marrow mesenchymal stem cells (BMSCs) under simulated weightlessness conditions. Therefore, we used the model of ground-based microgravity simulated by disuse osteoporosis patients and tail suspension in mice to simulate microgravity in vivo, and measured the expression of PHF8 in bone tissue. Subsequently, we used the 2D gyroscope to simulate the weightless effect on bone marrow mesenchymal stem cells.”
10. Jörges B, Bury N, McManus M, Bansal A, Allison RS, Jenkin M, Harris LR.The impact of gravity on perceived object height.npj Microgravity. 2024 Oct 4;10(1):95.Note: From the abstract: “Altering posture relative to the direction of gravity, or exposure to microgravity has been shown to affect many aspects of perception, including size perception. Our aims in this study were to investigate whether changes in posture and long-term exposure to microgravity bias the visual perception of object height and to test whether any such biases are accompanied by changes in precision. We also explored the possibility of sex/gender differences. Two cohorts of participants (12 astronauts and 20 controls, 50% women) varied the size of a virtual square in a simulated corridor until it was perceived to match a reference stick held in their hands. Astronauts performed the task before, twice during, and twice after an extended stay onboard the International Space Station. On Earth, they performed the task of sitting upright and lying supine. …”
11. Krotkova OA, Danilov GV, Galkin MV, Kuleva AY, Kaverina MY, Enikolopova EV, Strunina YV, Enikolopov GN.Dissociation of cognitive changes under unilateral exposure of the hippocampus to radiation.Hum Physiol. 2024 Sep 26;50(2):87-98.
12. Furrer R, Handschin C.Molecular aspects of the exercise response and training adaptation in skeletal muscle.Free Radic Biol Med. 2024 Oct;223:53-68.
13. Gonzalez Viejo C, Harris N, Tongson E, Fuentes S.Exploring consumer acceptability of leafy greens in Earth and space immersive environments using biometrics.npj Sci Food. 2024 Oct 9;8(1):81.Note: From the abstract: “This study used univariate and multivariate analysis on data from pick-and-eat leafy greens to assess self-reported and biometric consumer sensory analysis in simulated microgravity using reclining chairs and space-immersive environments.” This article may be obtained online without charge.
14. Zhao M.Food systems for long-term spaceflight: Understanding the role of non-nutrient polyphenols in astronauts’ health.Heliyon. 2024 Oct 15;10(19):e37452..Note: This article may be obtained online without charge.
15. Dugrenot E, Guernec A, Orsat J, Guerrero F.Gene expression of decompression sickness-resistant rats through a miRnome/transcriptome crossed approach.Commun Biol. 2024 Oct 2;7:1245.Note: This article may be obtained online without charge.

astrobiology, space biology , space medicine, microgravity,