NASA Spaceline Current Awareness List #1,204 12 June 2026 (Space Life Science Research Results)

The abstract in PubMed or at the publisher’s site is linked when available and will open in a new window.

Papers deriving from NASA support:

1. Basner M, Rennie K, Moore TM, Gur RC, Smith MG, Nasrini J, Hermosillo E, Ecker AJ, Schneller V, Jones CW, van den Berg FP, Johannes B.Proximity measurements for objective assessments of crew cohesion in an antarctic space analog environment.Front Psychol. 2026 Jun 8;17:1783846.PI: M. BasnerNote: This article may be obtained online without charge.
   
   Journal Impact Factor: 2.9
   
   Funding: “This work was supported by the NASA through grant NNX14AM81G (MB) and by the ESA through grant AO-13-Concordia-13 (BJ).”
2. Curry A, Bunchek J, Morales C, Khodadad C, Hummerick M, Spern C, Massa G, Smith T.Sowing in space: Seed film enables crew-planted crops on the International Space Station.Acta Astronaut. 2026 Jun 9. Online ahead of print.Journal Impact Factor: 3.4
   
   Funding: “This research was funded by NASA through the Biological and Physical Sciences Space Biology Program and is part of a series of Veggie Technology Demonstrations.”
3. Opdensteinen P, Lewin K, Jain A, Copeland A, Copeland J, Ghazinejad M, Steinmetz NF.Streamlined molecular farming of plant virus therapeutics for spaceflight and other low-resource environments.npj Science of Plants. 2026 Jun 5;2(1):16.PI: P. OpdensteinenNote: A random positioning machine was used to simulate microgravity in this study. This article may be obtained online without charge.
   
   Journal Impact Factor: Not available for this journal
   
   Funding: “P.O. was supported through a TRISH postdoctoral fellowship by the Translational Research Institute for Space Health (TRISH) through NASA Cooperative Agreement NNX16AO69A. This work was supported in part by the National Institutes of Health under grant number R01-CA274640. The authors thank Dr. Jingjing Zou, who provided support and expertise in statistical data analysis. The authors thank the University of California, San Diego-Cellular and Molecular Medicine Electron Microscopy Core (UCSD-CMM-EM Core, RRID: SCR_022039) for equipment access and technical assistance. The UCSD-CMM-EM Core is partly supported by the National Institutes of Health (S10OD023527).”
4. Bonarrigo LE, Li I, Comstock DC, Baldonado KM, Rees W, Clark TK, Miller LM, Vance EA, Robinson S, Szafir D, Hayman AP.Neural activation is enhanced with operational task ecological validity during complex cognitive tasks.Front Hum Neurosci. 2026 May 21;20:1825048.PIs: T.K. Clark, S. RobinsonNote: This article may be obtained online without charge.
   
   Journal Impact Factor: 2.7
   
   Funding: “This material was based upon work supported by the National Aeronautics and Space Administration under Grant No. 80JSC019N0001.”
5. Strock NC, Varanoske AN, Allen JR, Frisco DJ.A systematic review identifying fitness metrics indicative of simulated astronaut extravehicular activity task performance.npj Microgravity. 2026 Jun 10. Early access article.Note: This article may be obtained online without charge.
   
   Journal Impact Factor: 5.1
   
   Funding: “This study was funded by the NASA Human Research Program; the funder had no role in study design or interpretation of the data, or writing of this manuscript.”
6. Marshall-Goebel K, Strangman G, Moestl S, Frett T, Tank J, Hoffmann F, Sangi-Haghpeykar H, Mulder E, Bershad E.Effects of artificial gravity on the vascular system during 60 days of strict head-down tilt bedrest.J Appl Physiol (1985). 2026 Jun 9. Online ahead of print.PI: E. BershadNote: This article may be obtained online without charge.
   
   Journal Impact Factor: 3.3
   
   Funding: “This work was funded by the National Aeronautics and Space Administration (NASA), Grant number NNX17AE04G (KMG, GS, HSH, EB).”

Other papers of interest:

1. Altaie S, Al-Sabawi AWS, Abdulla AA, Junaid M, Alrawi A, Faisal RM, AlNeaimy KSA, Altaee MS, Ahmed AW, Xuexin D, Alnada Q.Investigating microgravity’s role in morphological changes, growth behavior, DNA damage, and cytotoxic responses of AMJ13 breast cancer cells.Life Sci Space Res. 2026 Jun 11. Online ahead of print.
2. Boyer M, Robinson A, Clark TK, Sunberg Z.Comprehensive evaluation of explanation types in a spaceflight-relevant human-autonomy teaming task.Hum Factors. 2026 Jun 6;187208261457703. Online ahead of print.
3. Feldblyum Le Blevennec MK.A role for negative genetic selection in space exploration and colonization.Bioethics. 2026 Jun 6. Online ahead of print.
4. Hou W, Wang L, Hu S, Luo L.Gut-muscle axis: A new perspective on microgravity induced skeletal muscle atrophy.Life Sci Space Res. 2026 Apr 8. Review. Online ahead of print.
5. Leal MA, Tovar D, de Pablo MA, Bonilla MA, Sánchez J, Goyanes G, Molina A, Leal M, Manjarrés I, Ríos I, Orozco MC, Tocarruncho M, Vergara C, Leone G, Rizzo C, San Martín J, Abrevaya XC, Luna C, Acevedo-Barrios R, Tchegliakova N.Deception Island (Antarctica) as an analog environment for human space missions: A comparative analysis of Gabriel de Castilla base (Spain) and Decepción base (Argentine).Acta Astronaut. 2026 Nov;248:36-67.Note: This article may be obtained online without charge.
6. Li W, Li Y, Wang F, Qi H, Fan B, Wang G, Wang Q.Tail-suspension model of simulated microgravity-induced functional dyspepsia in rats: Behavioral, motility, and brain-gut peptide alterations.Int J Mol Sci. 2026 May 29;27(11):4915.Note: Hindlimb unloading study. This article may be obtained online without charge.
7. Maurya S, Singh A.A comprehensive review of bioinformatics databases supporting space biology and omics research in microgravity.Life Sci Space Res. 2026 Jun 4. Review. Online ahead of print.
8. Raza MA, Aziz S.Pharmacist roles across the space mission pathway.Innov Pharm. 2025 Oct 24;16(3):10.24926/iip.v16i3.6591.Note: This article may be obtained online without charge.
9. Reynolds RJ, Day SM.Astronaut life expectancy and the limits of general population comparisons.npj Microgravity. 2026 Jun 8. Early access article.Note: This article may be obtained online without charge.
10. Bailey DM, Stacey BS, Ma Y, Washio T, Tsukamoto H, Owens TS, Calverley TA, Fall L, Marley CJ, Iannetelli A, Hashimoto T, Ando S, Ogoh S, Marchi N, Butkovic J, Mumlek I, Parry B, Vrselja Z, Pawelczyk JA, Bartsch RP.Network oscillatory dynamics accompany cerebral bioenergetic defence in hypoxia.J Cereb Blood Flow Metab. 2026 Jun 4;271678×261447119. Online ahead of print.Note: This article may be obtained online without charge.
11. Gao Y, Ge L, Xiao T, Du F, Chen J, Li M, Chang W, Yang Y, Zhang JV.Stage-dependent DNA damage and mitochondrial dysfunction under simulated microgravity constrain oocyte maturation and are mitigated by melatonin.Cell Commun Signal. 2026 Jun 11. Online ahead of print.Note: A rotating cell culture system was used in this study to simulate microgravity. This article may be obtained online without charge.
12. Giordo R, Sanna C, Camboni S, Maccioccu P, Manca A, Pantaleo A, Posadino AM, Pintus G.Simulated microgravity induces a NOX-sensitive oxidative response that is attenuated by resveratrol in human endothelial cells.Sci Rep. 2026 Jun 5. Early access article.Note: A 3D random positioning machine was used in this study to simulate microgravity. This article may be obtained online without charge.
13. Lecoq PE, Viraye G, Dupuis C, Benoit-Gonin X, Aider JL, Peyrin JM.Influence of gravity variations on the activity of neuronal spheroids in an acoustic trap.npj Microgravity. 2026 Jun 9. Early access article.Note: From the abstract: “Among biological models, cell culture constitutes an important paradigm that allows rapid examination of cell phenotype and behavior. While cell cultures are classically grown on a 2D substrate, the recent development of organoid technologies represents a paradigmatic shift in biological experimentation as they pave the way for reconstructing of minimalist organs in 3D. Manipulating these 3D cell assemblies presents a considerable challenge. While there is growing interest in studying the behavior of cells and organs in the space environment, manipulating 3D cultures in microgravity remains a challenge. But with cellular research underway aboard the International Space Station (ISS), optimizing techniques for handling 3D cellular assemblies is essential. Here, in order to cultivate 3D models of spheroids in microgravity, we developed and used an acoustic bioreactor to trap levitating cellular organoids in a liquid cell culture medium.” This article may be obtained online without charge.
14. Mathyk BA, Shukla R, Kumar V, Mishra SP, Pandya S, Patten N, Gerardi K, Beatty HW, Persad AH, Imudia AN, Yadav H, Jain S.Parabolic flight induces site specific microbiome changes in women.Front Microbiol. 2026 May 25;17:1817099.Note: This article is part of Research Topic “Systems of Integration: Metabolomic Signatures of Microbial Symbioses in Eubiosis and Dysbiosis” (https://www.frontiersin.org/research-topics/74078/systems-of-integration-metabolomic-signatures-of-microbial-symbioses-in-eubiosis-and-dysbiosis/articles) and may be obtained online without charge.
15. Sinyakova G, Diagne M, Banville M, Guo L, Wu Q, Enabulele I, Zhang X, Curtin K, Luban M, Hollos P, Divieti Pajevic P.Novel female murine alveolar osteoblasts responsive to hormones and mechanical forces.Bone. 2026 Oct;211:117957.