NASA Spaceline Current Awareness List #1,201 22 May 2026 (Space Life Science Research Results)

The abstract in PubMed or at the publisher’s site is linked when available and will open in a new window.

Papers deriving from NASA support:

1. Enguita FJ, Leitão AL, Beheshti A. A systems biology approach to discovery and validation of MicroRNA signature health risks associated with the space environment.In: Bizzarri M, ed. Methods Mol Biol. Vol. 3000. New York, NY: Humana, 2026. p. 123-43.PI: A. BeheshtiFunding: “A.B. was supported by research funding from the NASA E.9 Space Biology Research Studies 2023 grant.”
2. Goel H, Spector E, Yardley G, Mosiman S, Krueger D, Binkley N, Sibonga J. Use of DXA-based software to identify astronauts at risk for persisting spaceflight-induced bone loss.Osteoporos Int. 2026 May 19. Online ahead of print.Note: This article is a Short Communication.
   
   Journal Impact Factor: 5.4
   
   Funding: J. Sibonga is affiliated with NASA Johnson Space Center.
3. Kubik A, Theriot CA, Tang A, Zawaski J, Saha J.Comparative pharmacogenomic coverage of ISS medications across regulatory, clinical, and research databases in human spaceflight.Life Sci Space Res. 2026 Apr 18. Online ahead of print.Journal Impact Factor: 2.8
   
   Funding: “This work was supported in part by the NASA Human Research Program, Space Operations Mission Directorate, and the NASA Human Health and Performance contract NNJ15HK11B.”
4. Brekker MA, Semel M, Korostenskij I, Krikourian O, Kelly KMW, Santos J, Lowe M, Mhatre S, Iyer J, Paul AM, Puukila S, Alwood JS, Shirazi-Fard Y, Rubinstein L, Goukassian D, Ronca AE, Tahimic CGT.Simulated space radiation exposure leads to long-term changes in molecular signatures of the heart.Life Sci Space Res. 2026 May 2. Online ahead of print.PI: C.G.T. TahimicNote: GeneLab is available at https://genelab.nasa.gov.
   
   Journal Impact Factor: 2.8
   
   Funding: “This work was supported by grants from the NASA Human Research Program to Candice G.T. Tahimic (80JSC019N0001-FLAGSHIP) and April E. Ronca (80JSC018N0001-FLAGSHIP). Candice G.T. Tahimic was also supported by start-up funds from the University of North Florida. Stephanie Puukila, Amber M. Paul and Linda Rubinstein were supported by fellowships from the NASA Space Biology Postdoctoral Program (NPP). We thank Dr. Peter Guida and staff for their excellent assistance during the GCR simulation studies at BNL. We also thank NASA GeneLab for assistance in RNA sequencing and bioinformatics analysis.”
5. Schmidt MA, Schmidt JC, Schmidt CM, Jones JA, Mason CE.Precision medicine in astronauts: Principles and targets in molecular assessment.In: Bizzarri M, ed. Methods Mol Biol. Vol. 3000. New York, NY: Humana, 2026. p. 311-46.PI: C.E. MasonFunding: PI reports NASA funding.
6. Willett JDS, Kim J, Sakharkar A, Park J, Agyemang AA, Saygili EA, Proszynski J, Nelson TM, Mason CE.The data science of health in space.Annu Rev Biomed Data Sci. 2026 May 18. Review. Online ahead of print.PI: C.E. MasonJournal Impact Factor: 6.0
   
   Funding: PI reports NASA funding.
7. Bennett JP, Wong MC, Liu YE, Kelly NN, Quon BK, Shepherd JA.Consumer technologies for personalized health: Feasibility of five-compartment body composition self-assessment using mobile devices.Obesity (Silver Spring). 2026 May 14. Online ahead of print.PI: J.A. ShepherdJournal Impact Factor: 4.7
   
   Funding: “This work is supported by the NASA Translational Research Institute for Space Health (TRISH) under Cooperative Agreement NNX16AO69A, award P700000425.”

Other papers of interest:

1. Anna S, Silvia S, Ferre ER.The human brain in space: A meta-analysis of neuroimaging evidence.Front Psychol. 2026 Apr 29;17:1748118. Review.Note: This article is part of Research Topic “Gravitational Influence on Human Cognition and Behavior: Emerging Research” (https://www.frontiersin.org/research-topics/66872/gravitational-influence-on-human-cognition-and-behavior-emerging-research/articles). The Research Topic also includes articles from previous Current Awareness Lists #1,186 https://doi.org/10.3389/fpsyg.2026.1713354 and #1,187 https://doi.org/10.3389/fpsyg.2025.1735072. This article may be obtained online without charge.
2. Bryson S.Space food: The intersection of agriculture and life support.In: Carberry C, Zucker R, eds. A Future Spacefaring Society: Establishing Human Life Beyond Earth. Cham: Springer Nature Switzerland, 2026. p. 133-53.
3. Kirby ED, Burles F, Frizzell TO, D’Arcy RCN, Iaria G.Monitoring cognitive brain function before and after spaceflight: Feasibility of brain vital signs.Space Sci Technol. 2026 Apr 23;6:0547.Note: This article may be obtained online without charge.
4. Kubota K.Beyond rescue: An auditable minimum care standard for commercial human spaceflight.Space Policy. 2026 Apr 21;101763.Note: This article may be obtained online without charge.
5. Ciocanel M-V, Nardini JT, Flores KB, Rutter EM, Sindi SS, Volkening A.Enhancing generalizability of model discovery across parameter space with multi-experiment equation learning for biological systems.PLOS Computational Biology. 2026 Apr 22;22(4):e1014161.Note: This article may be obtained online without charge.
6. García-Florentino C, Bergamo I, Fornaro T, Alberini A, Marinoni N, Merlini M, Biancalani S, Renzi F, Poggiali G, Battistuzzi M, Hausrath EM, Brucato JR.L-histidine in nontronite: Stability under Martian-like UV irradiation to assist life detection on Mars.Sci Rep. 2026 May 18. Early access articles.Note: This article may be obtained online without charge.
7. Hazra S, Palit S, Russomano T, Ghosh G, Sannigrahi P.Enabling living in space through modern innovations in space medicine: A perspective on tissue-on-a-chip technology.Front Space Technol. 2026 Jan 5;6:1725575.Note: This article is part of Research Topic “Living in Space” (https://www.frontiersin.org/research-topics/71808/living-in-space). The Research Topic includes articles from previous Current Awareness List #1,172 https://doi.org/10.3389/frspt.2025.1704391 and https://doi.org/10.3389/frspt.2025.1675939. Additional articles will be forthcoming and may be found in the link to the Research Topic. This article may be obtained online without charge.
8. Marchal S, Hellwig P, Schmidt C, Kopp S, Grimm D, Walles H, Walles T, Wiese-Rischke C, Krüger M.A bioartificial 3D bronchial epithelial airway model to study lunar hay fever on Earth.Trends Biotechnol. 2026 May 15. Online ahead of print.Note: This article may be obtained online without charge.
9. Tonietti L, Esposito M, Leggiero M, Bunn F, Eades LJ, Cordone A, Horsfall L, Covone G, Cockell CS, Giovannelli D, Rotundi A, Santomartino R.Bioleaching of critical trace metals by Sphingomonas desiccabilis: Substrate-driven selectivity in Earth and space analogues.Front Microbiol. 2026 Apr 9;17:1741305.Note: This article is part of Research Topic “Microbial Interactions with Metals/Minerals: From Environmental Aspects to Applications” (https://www.frontiersin.org/research-topics/67203/microbial-interactions-with-metalsminerals-from-environmental-aspects-to-applications) and may be obtained online without charge.
10. van den Nieuwenhof DWA, Vergos K, Thierry S, van den Hoogen FJA, Hinkelbein J.Development and proof-of-concept validation of a neutral buoyancy testbed for cricothyrotomy evaluation in microgravity.Acta Astronaut. 2026 May 16. Online ahead of print.Note: This article may be obtained online without charge.
11. Zhong R, Yang Q, Wang M, Chang W, Chen K, Sun Y.Optimized experimentation for the WormChip cartridge enables lifelong tracking and high-content phenotyping of multi-strain C. elegans toward advanced space biology.Life Sci Space Res. 2026 May 18. Online ahead of print.
12. Dumais R, Suckow E, Ainab I, Zirille F, Forbes LM, Lawley JS, Cornwell WK.Cardiovascular exercise physiology under hypoxia, microgravity, and heat stress: A review with public health implications.Int J Environ Res Public Health. 2026 Apr 30;23(5):594. Review.Note: This article may be obtained online without charge.
13. Tomaz da Silva M, Joshi AS, Roy A, Hornberger TA, Kumar A.TAK1 regulates skeletal muscle mass, hypertrophic signaling, and metabolic homeostasis in male and female mice.Faseb j. 2026 May 12;40(10):e71893.Note: This article may be obtained online without charge.
14. Vaněček D, Kursch M, Şen E, Rehman IU, Yorulmaz YI.Exploring how textual complexity affects cognitive load during reading: An eye-tracking study.Sci Rep. 2026 May 18. Early access article.Note: This article may be obtained online without charge.
15. Hong H, Guo S, Liu Z, Sang N, Wang H, Tian D, Ye L.Enhanced space-variant deblurring of spacecraft images via detail-preserving techniques.Sci Rep. 2026 May 15. Early access article.Note: From the abstract: “During spacecraft launch, flight, and docking operations, monitored images often suffer from spatially variant blur caused by atmospheric turbulence, defocusing, and relative motion. To address this challenge, we propose a novel unsupervised deblurring framework tailored specifically for spacecraft imagery.” This article may be obtained online without charge.
16. Bizzarri M.Biomedicine and biotechnology in space: An introduction.In: Bizzarri M, ed. Methods Mol Biol. Vol. 3000. New York, NY: Humana, 2026. p. 3-17.
17. van Loon J.Hypergravity, microgravity, and animal research.In: Bizzarri M, ed. Methods Mol Biol. Vol. 3000. New York, NY: Humana, 2026. p. 24-45.
18. Nikitiuk AS, Bayandin YV, Naimark OB.Assessing the effects of microgravity on eukaryotic cells using a statistical thermodynamic approach.In: Bizzarri M, ed. Methods Mol Biol. Vol. 3000. New York, NY: Humana, 2026. p. 47-60.
19. Pais M, Cahill T, López-Campos GH, Hardiman G.Multiscale modeling and systems biology in microgravity investigations.In: Bizzarri M, ed. Methods Mol Biol. Vol. 3000. New York, NY: Humana, 2026. p. 61-95.
20. Olanrewaju GO, Szewczyk NJ, Willis CRG.Transcriptomics in space: A basic R pipeline for analyzing bulk RNA-sequencing data.In: Bizzarri M, ed. Methods Mol Biol. Vol. 3000. New York, NY: Humana, 2026. p. 99-122.
21. Catizone A, Tafani M, Berardini M, Ricci G.The cytoskeleton in space.In: Bizzarri M, ed. Methods Mol Biol. Vol. 3000. New York, NY: Humana, 2026. p. 145-61.
22. Fuso A.Epigenetics in space: The dynamic cellular response.In: Bizzarri M, ed. Methods Mol Biol. Vol. 3000. New York, NY: Humana, 2026. p. 163-82.
23. Di Nisio E, Cacci E, Lupo G, Negri R.Modulation of cell-to-cell adhesion and interaction with the extracellular matrix in microgravity conditions.In: Bizzarri M, ed. Methods Mol Biol. Vol. 3000. New York, NY: Humana, 2026. p. 185-95.
24. Di Nisio E, Cacci E, Lupo G, Negri R.Modulation of cell-to-cell adhesion and interaction with the extracellular matrix in microgravity conditions.In: Bizzarri M, ed. Methods Mol Biol. Vol. 3000. New York, NY: Humana, 2026. p. 185-95.
25. Atiakshin D, Shishkina V, Buchwalow IB, Tiemann M.Histochemistry and immunohistochemistry in space biology: Analysis of the functional morphology of the tissue microenvironment.In: Bizzarri M, ed. Methods Mol Biol. Vol. 3000. New York, NY: Humana, 2026. p. 197-234.
26. Monti N, Galante E, Querqui A, Cucina G, Angeloni A, Bizzarri M.Ovarian reproductive and endocrine function investigated in microgravity environment.In: Bizzarri M, ed. Methods Mol Biol. Vol. 3000. New York, NY: Humana, 2026. p. 235-50.
27. Blackburn D, Rahman B, Saroyia AP, Parish AJ, Driscoll M, Szewczyk NJ, Vanapalli SA, Samuel BS.Defining microbiome impact on host physiology during spaceflight using Caenorhabditis elegans.In: Bizzarri M, ed. Methods Mol Biol. Vol. 3000. New York, NY: Humana, 2026. p. 251-75.
28. Sforza ML, Chirivì M, Bearzi C, Perotto G, Rosa P, Petronella F, Rizzi R, De Sio L.3D bioprinted tumor constructs for photothermal therapy: Emerging opportunities in microgravity research.In: Bizzarri M, ed. Methods Mol Biol. Vol. 3000. New York, NY: Humana, 2026. p. 279-86.
29. Pontecorvi P, Marchese C.Regenerative medicine in space: Advancing bone repair with adipose-derived stem cells and bone-on-chip technology.In: Bizzarri M, ed. Methods Mol Biol. Vol. 3000. New York, NY: Humana, 2026. p. 287-300.
30. Sanders LM, Costes SV.Integrated platforms to further advance space biology research.In: Bizzarri M, ed. Methods Mol Biol. Vol. 3000. New York, NY: Humana, 2026. p. 303-10.