NASA Spaceline Current Awareness List #1,089 1 March 2024 (Space Life Science Research Results)

Papers deriving from NASA support

1. Fois M, Diaz-Artiles A, Zaman SY, Ridolfi L, Scarsoglio S.Linking cerebral hemodynamics and ocular microgravity-induced alterations through an in silico-in vivo head-down tilt framework.npj Microgravity. 2024 Feb 27;10:22.PI: A. Diaz-ArtilesNote: From the abstract: “Head-down tilt (HDT) has been widely proposed as a terrestrial analog of microgravity and used also to investigate the occurrence of spaceflight-associated neuro-ocular syndrome (SANS), which is currently considered one of the major health risks for human spaceflight. We propose here an in vivo validated numerical framework to simulate the acute ocular-cerebrovascular response to 6° HDT, to explore the etiology and pathophysiology of SANS.” This article may be obtained online without charge.
   
   Journal Impact Factor: 5.1
   
   Funding: “This work has been partially supported by the NASA Human Research Program, grant number 80NSSC20K1521, and by the Australian-American Fulbright Commission.”
2. Burke M, Wong K, Talyansky Y, Mhatre SD, Mitchell C, Juran CM, Olson M, Iyer J, Puukila S, Tahimic CGT, Christenson LK, Lowe M, Rubinstein L, Shirazi-Fard Y, Sowa MB, Alwood JS, Ronca AE, Paul AM.Sexual dimorphism during integrative endocrine and immune responses to ionizing radiation in mice.Sci Rep. 2024 Feb 26;14:7334.PI: L.K. ChristensonNote: This article may be obtained online without charge.
   
   Journal Impact Factor: 4.6
   
   Funding: “This work was supported by the Embry-Riddle Aeronautical University startup fund (AMP), the NASA Human Research Program (HRP) Human Factors Behavioral Performance Element Grant 18-18FLAG-2-0028 (AER), NNX15AB48G (LKC), and 80JSC019N0001-FLAGSHIP (CGTT).”
3. Keune JA, Wong CP, Branscum AJ, Menn SA, Iwaniec UT, Turner RT.Bone marrow adipose tissue is not required for reconstitution of the immune system following irradiation in male mice.Int J Mol Sci. 2024 Feb 6;25(4):1980.PI: R.T. TurnerNote: This article is part of Special Issue “New Insights into Adipose Tissue Metabolic Function and Dysfunction 2.0” (https://www.mdpi.com/journal/ijms/special_issues/WL0V1J2WQ0). Additional articles will be forthcoming and may be found in the link to the Special Issue. This article may be obtained online without charge.
   
   Journal Impact Factor: 2.5
   
   Funding: “This work was supported by the National Aeronautics and Space Administration (80NSSC19K0430) and the National Institute of Health (AR060913, AR066811).”
4. Wang Z, Xie H, Chien JH.The margin of stability is affected differently when walking under quasi-random treadmill perturbations with or without full visual support.PeerJ. 2024 Feb 19;12:e16919.Note: This article may be obtained online without charge.
   
   Journal Impact Factor: 3.06
   
   Funding: “The Natural Science Foundation of Sichuan Province No. 2022NSFSC1512 supported Zhuo Wang in completing writing the content of this study. The NASA EPSCoR NNX11AM06A supported this original data collection and analysis for the corresponding author, Jung Hung Chien.”
5. Barcenilla BB, Kundel I, Hall E, Hilty N, Ulianich P, Cook J, Turley J, Yerram M, Min J-H, Castillo-González C, Shippen DE.Telomere dynamics and oxidative stress in Arabidopsis grown in lunar regolith simulant.Front Plant Sci. 2024 Feb 15;15:1351613.PI: D.E. ShippenNote: This article is part of Research Topic “Progressing the Future of Space Agriculture” (https://www.frontiersin.org/research-topics/52433/progressing-the-future-of-space-agriculture#overview). The Research Topic also includes articles from previous Current Awareness Lists #1,055 https://doi.org/10.3389/fpls.2023.1194753, #1,069 https://doi.org/10.3389/fpls.2023.1265458, #1,070 https://doi.org/10.3389/fpls.2023.1284529, and #1,085 https://doi.org/10.3389/fpls.2023.1289208. This article may be obtained online without charge.
   
   Journal Impact Factor: 5.6
   
   Funding: “The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This work was supported by the National Institutes of Health (R01 GM065383 to DS) and the National Aeronautics and Space Administration (80NSSC23K0302 to DS).”

Other papers of interest:

1. Baranov VM, Katuntsev VP, Tarasenkov GG, Khudiakova EP, Sedelkova VA, Alferova IV, Shushunova TG.Studies of the activity of the central respiratory mechanism in long-duration space missions.Hum Physiol. 2024 Jan 24;49(7):780-6. Review.
2. Li Z, Wu J, Zhao T, Wei Y, Xu Y, Liu Z, Li X, Chen X.Microglial activation in spaceflight and microgravity: Potential risk of cognitive dysfunction and poor neural health.Front Cell Neurosci. 2024 Feb 15;18:1296205. Review.Note: This article is part of Research Topic “Space and Neural Cell: The Impact of Space Environment on Neurological Function and Their Molecular Mechanistic Insights” (https://www.frontiersin.org/research-topics/53086/space-and-neural-cell-the-impact-of-space-environment-on-neurological-function-and-their-molecular-mechanistic-insights#overview). The Research Topic also includes articles from previous Current Awareness Lists #1,072 https://doi.org/10.3389/fncel.2023.1275771 and #1,081 https://doi.org/10.3389/fncel.2023.1252958. This article may be obtained online without charge.
3. Huerta R, Kaduk SI, Fatai L, Rusch H, Weber T, Sammito S.A built-in guidance system to monitor vital signs in space and on EarthAerosp Med Hum Perform. 2024 Mar;95(3):139-46.
4. Nardi L, Davis NM, Sansolini S, Baratto de Albuquerque T, Laarraj M, Caputo D, de Cesare G, Shariati Pour SR, Zangheri M, Calabria D, Guardigli M, Balsamo M, Carrubba E, Carubia F, Ceccarelli M, Ghiozzi M, Popova L, Tenaglia A, Crisconio M, Donati A, Nascetti A, Mirasoli M.APHRODITE: A compact lab-on-chip biosensor for the real-time analysis of salivary biomarkers in space missions.Biosensors (Basel). 2024 Jan 30;14(2):72.Note: This article is part of Special Issue “Biosensors and Diagnostic Platforms in Support of Global Health, Antimicrobial Stewardship, Food Sustainability, and Water-Environment Quality 2023” (https://www.mdpi.com/journal/biosensors/special_issues/MM3P8S3R0N) and may be obtained online without charge.
5. Rudolf AM, Hood WR.Mitochondrial stress in the spaceflight environment.Mitochondrion. 2024 May;76:101855. Review.
6. Chopra S, Singh SN, Mathur P.Nutritional fuelling for microgravity environment of space missions.Curr Nutr Food Sci. 2024;20(4):450-65.
7. Luchitskaya ES, Funtova II.Possibilities of studying force and energy characteristics of the cardiac muscle in microgravity using ballistocardiography.Hum Physiol. 2024 Jan 26;49(7):787-92.Note: From the article: “The article is devoted to the assessment of force and energy characteristics of the heart muscle in microgravity using the method of spatial ballistocardiography.”
8. Mortazavi SMJ, Rafiepour P, Mortazavi SAR, Razavi Toosi SMT, Shomal PR, Sihver L.Radium deposition in human brain tissue: A Geant4-DNA Monte Carlo toolkit study.Z Med Phys. 2024 Feb;34(1):166-74.
9. Shafirkin AV, Vasin AL, Tatarkin SV.On the substantiation of dose-modifying factors DMF_im and DMF_del, which characterize modification of the immediate and delayed body responses to radiation by combined effects of stress factors during long-term orbital and exploration missions.Hum Physiol. 2024 Jan 26;49(7):758-71.Note: The spaceflight information is not available in the abstract.
10. Tran MT, Ho CNQ, Hoang SN, Doan CC, Nguyen MT, Van HD, Ly CN, Le CPM, Hoang HNQ, Nguyen HTM, Truong HT, To QM, Nguyen TTT, Le LT.Morphological changes of 3T3 cells under simulated microgravity.Cells. 2024 Feb 15;13(4):344.Note: This article may be obtained online without charge.
11. Blue RS, Ong KM.Handheld sonographic cardiovascular imaging under hypergravity conditions.Aerosp Med Hum Perform. 2024 Mar;95(3):158-64.
12. Gushchin VI, Ryumin OO, Karpova OI, Rozanov IA, Shved DM, Yusupova AK.Perspectives of psychological support in future exploration missions.Hum Physiol. 2024 Jan 26;49(7):750-7.
13. Cole JC AA, Chakarvarty S, Jahangiri FR.The effects of microgravity on EEG recordings: A systematic review.J of Neurophysiological Monitoring. 2024 Feb 21;2(2):14-24. Review.Note: This article may be obtained online without charge.
14. Rangdal A PA, Shadpoor B, Sherman LS, Homsi E.A theory of gravitational generation to mitigate space-induced low gravity – Relevance to premature aging in space.Int J Transl Sci. 2024 Feb 5;(1):77-96.Note: This article may be obtained online without charge.
15. Meng Q, Xu C, Zhang L, Zhang H.Simulations of n-dodecane/oxygen/nitrogen cellular detonations.Acta Astronaut. 2024 Feb 25. Online ahead of print.
16. Treigyte V, Chaillou T, Eimantas N, Venckunas T, Brazaitis M.Passive heating-induced changes in muscle contractile function are not further augmented by prolonged exposure in young males experiencing moderate thermal stress.Front Physiol. 2024 Feb 26;15:1356488.Note: This article is part of Research Topic “Acute and Chronic Responses to Heat Stress to Optimize Health and Performance” (https://www.frontiersin.org/research-topics/61190/acute-and-chronic-responses-to-heat-stress-to-optimize-health-and-performance/overview). Additional articles will be forthcoming and may be found in the link to the Research Topic. This article may be obtained online without charge.
17. Zhang J, Gao Y, Yan J.Roles of myokines and muscle-derived extracellular vesicles in musculoskeletal deterioration under disuse conditions.Metabolites. 2024 Jan 26;14(2):88. Review. Online ahead of print.Note: This article is part of Special Issue “Impact of Exercise on Energy and Muscle Metabolism” (https://www.mdpi.com/journal/metabolites/special_issues/8FKZU3CDC5). Additional articles will be forthcoming and may be found in the link to the Special Issue. This article may be obtained online without charge.
18. Zhang Y, Zhan Y, Guo K, Zheng Y, Tang L, Guo J, Liang J.Contrastive disentanglement for quantitative ultrasound muscle atrophy evaluation.IEEE Trans Biomed Eng. 2024 Feb 23. Online ahead of print.Note: This article may be obtained online without charge.
19. Hoffman WR, McNeil M, Tvaryanas A.The untapped potential of narrative as a tool in aviation mental health and certification.Aerosp Med Hum Perform. 2024 Mar;95(3):165-6.

Astrobiology, space biology,