NASA Spaceline Current Awareness List #1,200 15 May 2026 (Space Life Science Research Results)

The abstract in PubMed or at the publisher’s site is linked when available and will open in a new window.

Papers deriving from NASA support:

1. Eklund A, Bäcklund T, Williams MA, Jan M.Telemetric lumbar cerebrospinal fluid pressure monitoring for spaceflight: A novel approach to spaceflight-associated neuro-ocular syndrome research.npj Microgravity. 2026 May 7. Early access article.PI: M.A. WilliamsNote: This article is a Brief Communication and is available online without charge.
   
   Journal Impact Factor: 5.1
   
   Funding: “This study was supported by Translational Research Institute through NASA NNX16AO69A and the Baylor College of Medicine Center for Space Medicine through a donation from the Polaris Program.”
2. Mirza S, Lan M, Chen B, Niemczak CE, Buckey JC.Different predictors for components of spaceflight-associated neuro-ocular syndrome.JAMA Ophthalmol. 2026 Apr 30. Online ahead of print.PI: J.C. BuckeyNote: This article is a Research Letter.
   
   Journal Impact Factor: 9.2
   
   Funding: “Buckey, Jay C. M.D., Dartmouth College. Role of the Cranial Venous Circulation in Microgravity-Associated Visual Changes, Human Research NCC 9-58-CA03401 HHC SANS SANS-10.”
3. Blue RS, Mulcahy RA, Kreykes AJ, Haddon R, Pattarini JM, Johansen BD, Suresh R.Infectious disease outcomes of NASA’s health stabilization program.npj Microgravity. 2026 May 8. Early access article.Note: This article may be obtained online without charge.
   
   Journal Impact Factor: 5.1
   
   Funding: R.A. Mulcahy, R. Haddon, J.M. Pattarini, B.D. Johansen, and R. Suresh are affiliated with NASA Johnson Space Center.
4. Kara G, Holcomb M, Tiwari A, Flinn H, Eimer T, Marshall A, Burke M, Park P, Court KA, Cooke JP, Godin B, Villapol S.Telomerase mRNA-lipid nanoparticles attenuate neuroinflammation after traumatic brain injury in mice.Neurotherapeutics. 2026 Apr;23(3):e00917.Note: This article may be obtained online without charge.
   
   Journal Impact Factor: 6.9
   
   Funding: “This study was supported by National Institutes of Health (NIH) grant R21NS106640 (S.V., B.G.) from the National Institute for Neurological Disorders and Stroke (NINDS) and NIH grant R56AG080920 (S. V.) from the National Institute on Aging (NIA). B.G. and J.P.C. acknowledge partial support from CDMRP HT9425-24-1-0842/ MB230026, RP200619 (Cancer Prevention Institute of Texas). J.P.C. acknowledges partial support from 80ARC023CA002, NASA.”
5. Kumar A, Maringanti R, Mathur T, Abe J, Le N, Xiao Y, Wang G, Mojiri A, Cooke JP, Jain A.Investigational new drug-enabling studies in a human vessel-chip: Are we there yet?Bioeng Transl Med. 2026 Mar 17;e70129.PI: A. JainJournal Impact Factor: 5.7
   
   Funding: “National Heart, Lung, and Blood Institute, Grant/Award Number: R01 HL157790; National Institute of Dental and Craniofacial Research, Grant/Award Number: R21DE035321; National Aeronautics and Space Administration, Grant/Award Number: 80ARC023CA002; US Army Medical Research (USAMRAA); National Science Academy, Grant/Award Number: 1944322; National Institutes of Health (NIH), Grant/Award Number: RO1 HL148338.”
6. Elkins-Tanton L, Newman D, Sheffer A, Krafton K.Highlighting a science strategy for human exploration of Mars.Proc Natl Acad Sci USA. 2026 May 19;123(20):e2611962123.Note: This article is an Editorial and may be obtained online without charge.
   
   Journal Impact Factor: 9.1
   
   Funding: “80HQTR22DA001/80HQTR23FA063/National Aeronautics and Space Administration (NASA).”

Other papers of interest:

1. Kim G, Park Y, Lim YK, Lee JW, Kang D, Lee DK, Lee JH, Song MS, Lee BH.Understanding spaceflight-induced oxidative stress and the critical role of diet and microbiome.Antioxidants. 2026 Apr 23;15(5):534. Review.Note: This article may be obtained online without charge.
2. Carbin DD.Variations in urinary microbiota on a short-duration space mission to the International Space Station.JU Open Plus. 2026 Feb;4(2):e00018.Note: This article is an Editorial Comment and may be obtained online without charge.
3. Kumar R, Waisberg E, Ong J.Chapter 27 – Advanced technologies in deep space exploration and clinical applications.In: Waisberg E, Ong J, Lee AG, eds. Fundamentals of Space Medicine and Clinical Technology. Academic Press, 2026. p. 415-24.
4. Fan Y, Liang X, Sun L, Shi Q, Le Y, Yue H, Ling S, Tian W, Shi Y, Zhong G, Xing W, Li Y, Du R, Liu Z, Li Y, Sun W, Pan J, Jin X, Liu Y, Zong F, Li Y, Li J.Multimodal magnetic resonance imaging reveals the combined effects of simulated microgravity and space radiation on brain structure and function.Fundamental Research. 2026 Apr 30. Online ahead of print.Note: This article may be obtained online without charge.
5. Gere Á, Szabó L, Tillmann B, Balogh C, Zákány F, Kovács T, Nagy P, Szarka M, Csernoch L, Dienes B.Proton radiation impairs mechanotransduction in C2C12 myoblasts.npj Microgravity. 2026 May 14. Early access article.Note: This article may be obtained online without charge.
6. Villanueva-Congote J, Smith S, Tinh Le T, Karachenets S, Marin-Urrego J, Hansen N, Dalton R, James E, Buckey J, Wollin DA, Sobel DW.Microgravity-related changes in urinary calcium and oxalate excretion: A systematic review of astronaut data.Urology. 2026 May 12. Review. Online ahead of print.
7. Andrade DC, Salazar-Ardiles C, García-Ordenes B, Bueno J, Arce-Alvarez A, Rodriguez-Fernandez M, Iturriaga R, Millet GP.Carotid body chemoreceptors: From mountain to space.Physiology (Bethesda). 2026 May 13. Review. Online ahead of print.Note: From the abstract: “This review summarizes current evidence and proposed potential similarities and bioconvergent mechanisms underlying human responses to both terrestrial and extraterrestrial environments.”
8. O’Sullivan C, Kohl TM, Konstas K, Mulet X, Chang KL, Hill MR, Polyzos A, Thornton AW.Review of carbon dioxide removal and recycling in space.npj Microgravity. 2026 May 12. Early access article.Note: This article may be obtained online without charge.
9. Atkin J, Pierson E, Gentry T, Oliveira Santos S.Bioremediation of lunar regolith simulant through mycorrhizal fungi and plant symbioses enables chickpea to seed.Sci Rep. 2026 Mar 5;16:7498.Note: This article may be obtained online without charge.
10. Clary JE, Conway MT, Paramkusham Y, Sedelnikova AV, Pope NJ, Roth CC, O’Connor SP, Steelman ZA.Design and validation of an electroporation-capable random positioning machine for the study of cell membrane permeabilization in simulated microgravity.Rev Sci Instrum. 2026 May 12;97(5):055209.Note: From the abstract: “Biomanufacturing is being explored as a potential solution for improved space logistics in austere environments. One potentially useful tool is electroporation-the delivery of exogenous DNA into cells using pulsed electric fields to increase cell membrane permeability. Electroporation has the potential to enable tunable bioreactors in a space environment through the targeted delivery of nucleic acids encoding proteins of interest and may also present a solution for disinfection, purification, and biomolecule extraction without requiring disposable reagents. Unfortunately, electroporation has not been studied using cells adapted to microgravity conditions, and it is possible that well-known cellular adaptations to microgravity will alter electroporation outcomes. Studying this phenomenon is complicated by the fact that electroporating cells in common microgravity simulators, such as the rotating wall vessel and the random positioning machine (RPM), is currently not feasible. In this work, we design and validate a custom, electroporation-capable RPM.”
11. Vadukoot Lazar M, Menon A, Gopalakrishna R.Microgravity as a translational model for metabolic dysfunction: Implications for obesity, insulin resistance, steatotic liver and pancreatic diseases.Front Endocrinol (Lausanne). 2026 Apr 23;17:1820707.Note: This article may be obtained online without charge.
12. Xu Y, Chen W, Hu Y, Wang H, Xie Y, Cheng Y, Lin Y, Wu X, Ren X, Cheng L, Wang N, Duan K, Chen H.Optic nerve cerebrospinal fluid drainage via lymphatic vessels in its sheath.npj Microgravity. 2026 May 13. Early access article.Note: This article may be obtained online without charge.
13. Marr B, Laakso H, Blimkie M, Cao A, Lee SH, Khan AUH.Limited immune perturbations in mice exposed to sustained low-dose ionizing radiation.Front Immunol. 2026 Apr 19;17:1642012.Note: This article is part of Research Topic “Occupational Low-Dose Ionizing Radiation Exposure and the Immune System: Findings and Future Research Goals” (https://www.frontiersin.org/research-topics/68769/occupational-low-dose-ionizing-radiation-exposure-and-the-immune-system-findings-and-future-research-goals) and may be obtained online without charge.
14. Núñez-Vázquez I, Morales-Garoffolo A, Pacheco-Ramos G, Mateos I.A study on students’ personality and motivation in the educational UCAnFly CubeSat project.Acta Astronaut. 2026 May 12. Online ahead of print.
15. Orr S, Gilmore NK, Pathak S, Edan HA, Langer H, Baar K, Christiansen BA.Age-dependent musculoskeletal changes during mechanical unloading with bisphosphonate treatment.Bone. 2026 Sep;210:117924.
16. Fernandez P, Linossier MT, Bareille MP, Billette DEVR, Antunes I, Van Ombergen A, Navasiolava N, Custaud MA, Strigini M, Vico L.ESA VIVALDI (1 & 2) Campaigns: Sex-specific bone responses to dry immersion-induced unloading.J Appl Physiol (1985). 2026 May 7. Online ahead of print.Note: This article may be obtained online without charge.
17. Chu T, Wu XH, Lv MY, You HH, Duan HZ, Fu XY, Liu Q, Liu X, Su D, Li B, Zhang G, Bai C, Li B, Hou DY.In situ self-assembled glycopeptide regulates tumor microenvironment for tumor immunotherapy.J Control Release. 2026 Jul 10;395:114999.
18. Faiss R, Girard O.Live high, train smart: Translating altitude physiology to best practice with mechanistic insights.Front Physiol. 2026 May 10;17:1834288.Note: This article is part of Research Topic “Physiological and Pathological Responses to Hypoxia and High Altitude, Volume IV” (https://www.frontiersin.org/research-topics/74860/physiological-and-pathological-responses-to-hypoxia-and-high-altitude-volume-iv/articles). The Research Topic also includes articles from previous Current Awareness Lists #1,183 https://doi.org/10.3389/fphys.2025.1724998, #1,186 https://doi.org/10.3389/fphys.2026.1746894, and #1,198 https://doi.org/10.3389/fphys.2026.1781613. This article may be obtained online without charge.

astrobiology, ISS, Microgravity, space biology, space life science, space medicine, spaceline, AbSciCon,