Origin & Evolution of Life

Reconstructing Early Microbial Life

By Keith Cowing
Status Report
q-bio.PE
November 23, 2024
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Reconstructing Early Microbial Life
Historical molecular sequences, which can be reconstructed via genomic and phylogenetic tools, can yield experimentally verified insights into ancient protein structure and chemical function. Function can then be mapped to independent biogeochemical records of life (78; 115). — q-bio.PE

For more than 3.5 billion years, life experienced dramatic environmental extremes on Earth. These include shifts from oxygen-less to over-oxygenated atmospheres and cycling between hothouse conditions and global glaciations.

Meanwhile, an ecological revolution took place. The planet evolved from one dominated by microbial life to one containing the plants and animals that are most familiar today. The activities of many key cellular inventions evolved early in the history of life, collectively defining the nature of our biosphere and underpinning human survival.

There is a critical need for a new disciplinary synthesis to reveal how microbes and their molecular systems survived ever changing global conditions over deep time. This review critically examines our current understanding of early microbial life and describes the foundations of an emerging area in microbiology and evolutionary synthetic biology to reconstruct the earliest microbial innovations.

Betul Kacar

Comments: Author accepted manuscript. Posted with permission from the Annual Review of Microbiology
Subjects: Populations and Evolution (q-bio.PE)
Cite as: arXiv:2406.09354 [q-bio.PE] (or arXiv:2406.09354v1 [q-bio.PE] for this version)
https://doi.org/10.48550/arXiv.2406.09354
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Submission history
From: Betul Kacar
[v1] Thu, 13 Jun 2024 17:40:44 UTC (959 KB)
https://arxiv.org/abs/2406.09354

Astrobiology

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