NASA Spaceline Current Awareness List #1,103 7 June 2024 (Space Life Science Research Results)

The abstract in PubMed or at the publisher’s site is linked when available and will open in a new window.

Papers deriving from NASA support:

1. Grant LK, Kent BA, Rahman SA, St Hilaire MA, Kirkley CL, Gregory KB, Clark T, Hanifin JP, Barger LK, Czeisler CA, Brainard GC, Lockley SW, Flynn-Evans EE.The effect of a dynamic lighting schedule on neurobehavioral performance during a 45-day simulated space mission.SLEEP Advances. 2024 May 30. Online ahead of print.PI: G.C. BrainardNote: From the introduction: “The present study compared a dynamic lighting schedule (DLS) to a standard lighting schedule (SLS) during 45-day missions in the Human Exploration Research Analog (HERA) habitat (Campaign 4) (https://www.nasa.gov/mission/hera/). This article may be obtained online without charge.
   
   Journal Impact Factor: Not available for this journal
   
   Funding: “This work was supported by NASA grant NNX15AM28G. BAK was supported by NIHNINDS K99/R00 NS109909-01. GCB and JPH were supported, in part, by NASA grant NNX15AC14G; the Nova Institute, and The Philadelphia Chapter of the Illuminating Engineering Society. EEE, CLK, and KBG were supported by NASA grant NNJ15ZSA001N.”
2. Poveda L, Devane K, Lalwala M, Gayzik FS, Stitzel JD, Weaver AA.Injury risk predictions in Lunar Terrain Vehicle (LTV) Extravehicular Activities (EVAs): A pilot study.Ann Biomed Eng. 2024 Jun 5.PI: A.A. WeaverNote: This article may be obtained online without charge.
   
   Journal Impact Factor: 3.8
   
   Funding: “This study was supported by a NASA Human Research Program Student Augmentation Award to NASA Grant No. NNX16AP89G.”
3. Smokovski I, Steinle N, Behnke A, Bhaskar SMM, Grech G, Richter K, Niklewski G, Birkenbihl C, Parini P, Andrews RJ, Bauchner H, Golubnitschaja O.Digital biomarkers: 3PM approach revolutionizing chronic disease management – EPMA 2024 position.Epma j. 2024 Jun;15(2):149-62.Note: This article may be obtained online without charge.
   
   Journal Impact Factor: 6.5
   
   Funding: R.J. Andrews is affiliated with NASA Ames Research Center.

Other papers of interest:

1. Murgia M, Rittweger J, Reggiani C, Bottinelli R, Mann M, Schiaffino S, Narici MV.Spaceflight on the ISS changed the skeletal muscle proteome of two astronauts.npj Microgravity. 2024 Jun 5;10(1):60.Note: ISS results. This article may be obtained online without charge.
2. Lee Satcher R, Fiedler B, Ghali A, Dirschl DR.Effect of spaceflight and microgravity on the musculoskeletal system: A review.JAAOS. 2024 Jun 15;32(12):535-41. Review.
3. Tölgyesi B, Altbäcker A, Barkaszi I, Stuckenschneider T, Braunsmann L, Takács E, Ehmann B, Balázs L, Abeln V.Effect of artificial gravity on neurocognitive performance during head-down tilt bedrest.npj Microgravity. 2024 Jun 5;10(1):59.Note: Head-down tilt bedrest study. This article may be obtained online without charge.
4. Jullienne A, Malo M, Shaw K, Zheng Y, Johnston JD, Kontulainen S, Chilibeck PD, Dadachova E, Obenaus A, Sarty GE.Musculoskeletal perturbations of deep space radiation: Assessment using a Gateway MRI.Life Sci Space Res. 2024 Aug;42:74-83.Note: From the abstract: “This review summarizes the current state of our knowledge on musculoskeletal consequences of spaceflight, especially with respect to radiation, and then elaborates how MRI can be used to monitor the deleterious effects of space travel and the efficacy of putative countermeasures.”
5. Liu H, Yu S, Liu B, Xiang S, Jiang M, Yang F, Tan W, Zhou J, Xiao M, Li X, Richardson JJ, Lin W, Zhou J.Space-efficient 3D microalgae farming with optimized resource utilization for regenerative food.Advanced Materials. 2024 Mar;2401172. Online ahead of print.Note: From the abstract: “Photosynthetic microalgae produce valuable metabolites and are a source of sustainable food that supports life without compromising arable land. However, the light self-shading, excessive water supply, and insufficient space utilization in microalgae farming have limited its potential in the inland areas most in need of regenerative food solutions. Herein, this work develops a 3D polysaccharide-based hydrogel scaffold for vertically farming microalgae without needing liquid media.”
6. Javaid A, Rasool S, Maqsood A.Analysis of visual and vestibular information on motion sickness in flight simulation.Aerospace. 2024 Feb 6;11(2):139.Note: This article is part of Section “Aeronautics” (https://www.mdpi.com/journal/aerospace/sections/aeronautics) and may be obtained online without charge.
7. Panwar KS, Huish EG, Law JL, Deans JT, Staples JR, Eisemon EO, Lum ZC.Revision total joint arthroplasty places a disproportionate burden on surgeons: A comparison using the National Aeronautics and Space Administration Task Load Index (NASA TLX).The Journal of Arthroplasty. 2024 Jun;39(6):1550-6.Note: NASA Task Load Index was used in this study.
8. Yang Q, Zhong R, Chang W, Chen K, Wang M, Yuan S, Liang Z, Wang W, Wang C, Tong G, Zhang T, Sun Y.WormSpace μ-TAS enabling automated on-chip multi-strain culturing and multi-function imaging of Caenorhabditis elegans at the single-worm level on the China Space Station.Lab Chip. 2024 May 31.
9. Chilvers NJS, Evans ZM, Clark AW, Mydin MI, Clark SC.Quantifying the effects of training in lung transplantation: Lessons from NASA.JHLT Open. 2024 Aug;5:100102. Online ahead of print.Note: From the abstract: “We prospectively collected the NASA-TLX data for 60 patients undergoing bilateral sequential lung transplantation. In 30 cases, the operation was performed entirely by the senior surgeon (SS) who implanted both lungs. In 30 operations, the senior surgeon implanted the right lung (SSR) and supervised a trainee implanting the left lung (TL).” This article may be obtained online without charge.
10. Giuliani G, Longo VD.Ketone bodies in cell physiology and cancer.Am J Physiol Cell Physiol. 2024 Mar 1;326(3):C948-c63. Review.Note: From the abstract: “Here, we explore the impact of ketone bodies (KBs) on mammalian cell physiology, including aging and tissue regeneration.”
11. Golov AK, Gavrilov AA.Cohesin-dependent loop extrusion: Molecular mechanics and role in cell physiology.Biochemistry (Mosc). 2024 May 6;89(4):601-25. Review.Note: From the abstract: “This review briefly summarizes the current understanding of the place and role of cohesin-dependent extrusion in cell physiology and presents a number of models describing the potential molecular mechanism of extrusion in a most compelling way. We conclude the review with a discussion of how the capacity of cohesin to extrude DNA loops may be mechanistically linked to its involvement in sister chromatid cohesion.”
12. Vicente EM, Grande Gutierrez N, Oakes JM, Cammin J, Gopal A, Kipritidis J, Modiri A, Mossahebi S, Mohindra P, Citron WK, Matuszak MM, Timmerman R, Sawant A.Integrating local and distant radiation-induced lung injury: Development and validation of a predictive model for ventilation loss.Med Phys. 2024 May 31. Online ahead of print.
13. Huo Y, Hao L, Sun M, Dai W, Kan G, Yang Z, Zhu S.Effects of long-term simulated weightlessness on retinal microcirculation and visual electrophysiology.Altern Ther Health Med. 2024 May 24. Online ahead of print.Note: Head-down tilt study.
14. Carhuaricra-Huaman D, Setubal JC.Step-by-step bacterial genome comparison.Methods Mol Biol. 2024 Jun 1;2802:107-34.
15. Fendi F, Abdullah B, Suryani S, Usman AN, Tahir D.Development and application of hydroxyapatite-based scaffolds for bone tissue regeneration: A systematic literature review.Bone. 2024 Jun;183:117075. Online ahead of print.
16. Lal H, Kumar V, Wang Y, Xie M, Young ME.Circadian rhythms in cardiovascular metabolism.Circulation Research. 2024 Mar 14;134(6):635-58. Review.Note: This article may be obtained online without charge.
17. Munteanu C, Turti S, Achim L, Muresan R, Souca M, Prifti E, Mârza SM, Papuc I.The relationship between circadian rhythm and cancer disease.International Journal of Molecular Sciences. 2024;25(11):5846.Note: This article is part of Special Issue “Molecular Insights in Circadian Rhythm and Metabolism” (https://www.mdpi.com/journal/ijms/special_issues/W12D3FJR43) and may be obtained online without charge.
18. Otobe Y, Jeong EM, Ito S, Shinohara Y, Kurabayashi N, Aiba A, Fukada Y, Kim JK, Yoshitane H.Phosphorylation of DNA-binding domains of CLOCK-BMAL1 complex for PER-dependent inhibition in circadian clock of mammalian cells.Proc Natl Acad Sci USA. 2024 Jun 4;121(23):e2316858121.Note: This article may be obtained online without charge.

Astrobiology, microgravity, space biology