NASA Spaceline Current Awareness List #1,082 12 January 2024 (Space Life Science Research Results)

SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at https://taskbook.nasaprs.com/Publication/spaceline.cfm. Please send any correspondence to Shawna Byrd, SPACELINE Current Awareness Senior Editor, [email protected].

Call for articles to cite in the weekly lists: Authors at NASA Centers and NASA PIs—do you have an article that has recently published or will publish in the upcoming weeks within a peer-reviewed journal and is in the scope of space life sciences? If so, send it our way! Send your article to the email address mentioned above. Articles received by Wednesday will appear within that week’s list—articles received after Wednesday will appear the following week.

Papers deriving from NASA support:

1. Hauserman MR, Ferraro MJ, Carroll RK, Rice KC.Altered quorum sensing and physiology of Staphylococcus aureus during spaceflight detected by multi-omics data analysis.npj Microgravity. 2024 Jan 8;10(1):2.PI: K.C. RiceNote: ISS results. This article may be obtained online without charge.
   
   Journal Impact Factor: 5.1
   
   Funding: “This study was funded by NASA grants 80NSSC19K0139 and 80NSSC21K0601 awarded to Kelly C. Rice. We thank the NASA Ames Research Center, NASA Life Sciences Data Archive (LSDA), and NASA Open Science Data Repository (OSDR) for providing the BRIC-23 S. aureus flight and ground control culture supernatant samples that were used in the secretomics experiments described in this study, in addition to secreted protein concentration data and total harvested CFU/plate data for FLT and GC samples.”
2. Vozenin MC, Alaghband Y, Drayson OGG, Piaget F, Leavitt R, Allen BD, Doan NL, Rostomyan T, Stabilini A, Reggiani D, Hajdas W, Yukihara EG, Norbury JW, Bailat C, Desorgher L, Baulch JE, Limoli CL.More may not be better: Enhanced spacecraft shielding may exacerbate cognitive decrements by increasing pion exposures during deep space exploration.Radiat Res. 2024 Jan 4. Online ahead of print.PI: C.L. Limoli/NSCORNote: From the abstract: “The pervasiveness of deep space radiation remains a confounding factor for the transit of humans through our solar system. Spacecraft shielding both protects astronauts but also contributes to absorbed dose through galactic cosmic ray interactions that produce secondary particles. The resultant biological effects drop to a minimum for aluminum shielding around 20 g/cm2 but increase with additional shielding. The present work evaluates for the first time, the impact of secondary pions on central nervous system functionality.”
   
   Journal Impact Factor: 3.4
   
   Funding: “NASA grant NNX15AI22G.”
3. Niclou A, Sarma M, Levy S, Ocobock C.To the extreme! How biological anthropology can inform exercise physiology in extreme environments.Comp Biochem Physiol A Mol Integr Physiol. 2023 Oct;248:111476. Review.PI: M. SarmaNote: This article appeared in Current Awareness list #1,059. It is appearing this week in the “NASA” section along with the PI and funding information.
   
   Journal Impact Factor: 2.3
   
   Funding: The source of funding is not stated in the acknowledgments of the article but this article was included in the PI’s bibliography for their Translational Research Institute for Space Health (TRISH) project and submitted to NASA Task Book.
4. Edwards S, Adams J, Tchernikov A, Edwards JG.Low-dose x-ray radiation induces an adaptive response: A potential countermeasure to galactic cosmic radiation exposure.Exp Physiol. 2024 Jan 5. Online ahead of print.PI: J.G. EdwardsNote: This article may be obtained online without charge.
   
   Journal Impact Factor: 2.7
   
   Funding: “NASA, Grant/Award Number: 80NSSC19K0436.”
5. Linhardt RM, Salas E.Examining the fluidity of innovation teams: A conceptual framework.Front Psychol. 2023 Dec 18;14:1296651. Review.PI: E. SalasNote: From the abstract: “This article focuses on how teams effectively integrate knowledge with diverse, and possibly fluid, team members and how teams can organize knowledge through planning and reflection to implement the idea successfully.” This article is part of Research Topic “Fluid Teams” (https://www.frontiersin.org/research-topics/52681/fluid-teams#overview) and may be obtained online without charge.
   
   Journal Impact Factor: 3.8
   
   Funding: PI reports NASA funding.
6. Raber J, Holden S, Kessler K, Glaeser B, McQuesten C, Chaudhari M, Stenzel F, Lenarczyk M, Leonard SW, Morré J, Choi J, Kronenberg A, Borg A, Kwok A, Stevens JF, Olsen C, Willey JS, Bobe G, Minnier J, Baker JE.Effects of photon irradiation in the presence and absence of hindlimb unloading on the behavioral performance and metabolic pathways in the plasma of Fischer rats.Front Physiol. 2024 Jan 8;14:1316186.PI: J.E. BakerNote: This article is part of Research Topic “Multi-omics Approaches for Understanding Space Flight Impact” (https://www.frontiersin.org/research-topics/36594/multi-omics-approaches-for-understanding-space-flight-impact#overview). The Research Topic also includes articles from previous Current Awareness Lists #1,014 https://doi.org/10.3389/fphys.2022.971282 and #1,056 https://doi.org/10.3389/fphys.2023.1215535. This article may be obtained online without charge.
   
   Journal Impact Factor: 4.0
   
   Funding: “The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This study was supported by NASA 80NSSC19K0498-P00001 ‘NIH 1S10RR027878-01’ and the development account of JR.”
7. Ma N, Mourkioti F.Ex vivo two-photon imaging of whole-mount skeletal muscles to visualize stem cell behavior.STAR Protoc. 2023 Dec 11;5(1):102772.PI: N. MaNote: This article may be obtained online without charge.
   
   Journal Impact Factor: Not available for this journal
   
   Funding: Special thanks to G. Ruthel, technical director at Penn Vet Imaging Core, for guidance with two-photon microscopy, supported by NIH (S10 OD021633). We acknowledge the support and technical expertise from the Biomechanics Core at the Penn Center for Musculoskeletal Disorders (P30AR069619). This study was supported by NIH/NIAMS (R01AR075914), DoD (W81XWH2211116), and NASA (80NSSC19K1602) to F.M.”
8. Totsline N, Kniel KE, Sabagyanam C, Bais HP.Simulated microgravity facilitates stomatal ingression by Salmonella in lettuce and suppresses a biocontrol agent.Sci Rep. 2024 Jan 9;14(1):898.Note: A 2D clinostat was used in this study. This article may be obtained online without charge.
   
   Journal Impact Factor: 4.6
   
   Funding: “Authors acknowledge NASA-EPSCoR for funding support.”

Other papers of interest:

1. Mao T, Fang Z, Chai Y, Deng Y, Rao J, Quan P, Goel N, Basner M, Guo B, Dinges DF, Liu J, Detre JA, Rao H.Sleep deprivation attenuates neural responses to outcomes from risky decision-making.Psychophysiology. 2023 Oct 31;e14465.Note: This article and the article directly below are not funded by NASA but include authors who are NASA Principal Investigators. This article may be obtained online without charge.
2. Goldschmied JR, Boland E, Palermo E, Barilla H, Dinges DF, Detre JA, Basner M, Sheline YI, Rao H, Gehrman P.Antidepressant effects of acute sleep deprivation are reduced in highly controlled environments.J Affect Disord. 2023 Nov 1;340:412-9.
3. Kimura Y, Nakai Y, Ino Y, Akiyama T, Moriyama K, Aiba T, Ohira T, Egashira K, Yamamoto Y, Takeda Y, Inaba Y, Ryo A, Saito T, Kumagai K, Hirano H.Changes in the astronaut serum proteome during prolonged spaceflight.Proteomics. 2024 Jan 7:e2300328. Online ahead of print.Note: ISS results. This article may be obtained online without charge.
4. Deshevaya EA, Fialkina SV, Shubralova EV, Tsygankov OS, Khamidullina NM, Vasilyak LM, Pecherkin VY, Shcherbakova VA, Nosovsky AM, Orlov OI.Survival of microorganisms during two-year exposure in outer space near the ISS.Sci Rep. 2024 Jan 3;14:334Note: From the introduction: “The goals of this work were the selection of microorganisms species for exposure and the study of the duration of it survival in open space near the ISS, as well as changes in radiation resistance and the influence of individual stress factors on the fungi strains.” This article may be obtained online without charge.
5. Mussagy CU, Pereira JFB, Pessoa A Jr.Microbial products for space nutrition.Trends Biotechnol. 2024 Jan 4. Online ahead of print.
6. Chavez A, Topolski C, Hicks J, Villafania M, Baez N, Burke M, Castillo H.Phenotypical changes in Escherichia coli K12 after prolonged exposure to simulated microgravity.Front Space Technol. 2024 Jan 10;4:1282850.Note: A 2D clinostat was used in this study.
7. Gu C, Sun Y, Mao M, Liu J, Li X, Zhang X.Mechanism of simulated lunar dust-induced lung injury in rats based on transcriptomics.Toxicol Res (Camb). 2024 Feb;13(1):tfad108.Note: From the abstract: “Lunar dust particles are an environmental threat to lunar astronauts, and inhalation of lunar dust can cause lung damage. The current study explored the mechanism of lunar dust simulant (CLDS-i) inducing inflammatory pulmonary injury.”
8. Krakos A.Lab-on-chip technologies for space research — Current trends and prospects.Microchimica Acta. 2023 Dec 14;191(1):31.Note: This article may be obtained online without charge.
9. Nie H-Y, Ge J, Liu K-G, Yue Y, Li H, Lin H-G, Yan H-F, Zhang T, Sun H-W, Yang J-W, Zhou J-L, Cui Y.The effects of microgravity on stem cells and the new insights it brings to tissue engineering and regenerative medicine.Life Sci Space Res. 2024 Jan 7. Review. Online ahead of print.
10. Puchkova AA, Shpakov AV, Katuntsev VP, Stavrovskaya DM, Primachenko GK.Cardiorespiratory reactions during submaximal exercise in humans after 14-day simulated lunar gravity.Hum Physiol. 2023 Dec 1;49(6):609-16.Note: Head-up bedrest results.
11. Romano LE, van Loon J, Izzo LG, Iovane M, Aronne G.Effects of altered gravity on growth and morphology in Wolffia globosa implications for bioregenerative life support systems and space-based agriculture.Sci Rep. 2024 Jan 3;14(1):410.Note: A random positioning machine was used in this study. This article may be obtained online without charge.
12. Hu L, Wu Z, Ru K, Liu H, Jia Y, Khan Z, Tian Z, Liu S, Xu X, Chen Z, Qian A.Chapter 10 – Bone cell mechanobiology and bone disease.In: Qian A, Hu L, eds. Bone Cell Biomechanics, Mechanobiology and Bone Diseases. Academic Press, 2024. p. 291-313.
13. Ibrahim Z, Khan NA, Qaisar R, Saleh MA, Siddiqui R, Al-Hroub HM, Giddey AD, Semreen MH, Soares NC, Elmoselhi AB.Serum multi-omics analysis in hindlimb unloading mice model: Insights into systemic molecular changes and potential diagnostic and therapeutic biomarkers.Heliyon. 2024 Jan 15;10(1):e23592.Note: Hindlimb unloading results.
14. Koryak YA, Prochiy RR, Knutova NS.Effect of three weeks of strict head down tilt bedrest on human muscle function and architecture.Human Physiology. 2023 Dec 23;49(6):589-604.Note: Head-down tilt bedrest study.
15. Moes MI, Elia A, Gennser M, Keramidas ME.Combined effects of mild hypothermia and nitrous-oxide-induced narcosis on manual and cognitive performance.Am J Physiol Regul Integr Comp Physiol. 2024 Jan 8. Online ahead of print.
16. Mutschler T, Furian M, Lichtblau M, Buergin A, Schneider SR, Appenzeller P, Mayer L, Muralt L, Mademilov M, Abdyraeva A, Aidaralieva S, Muratbekova A, Akylbekov A, Shabykeeva S, Sooronbaev TM, Ulrich S, Bloch KE.Effect of altitude and acetazolamide on postural control in healthy lowlanders 40 years of age or older. Randomized, placebo-controlled trial.Front Physiol. 2024 Jan 4;14:1274111.Note: This article may be obtained online without charge.
17. Pastushkova LK, Goncharova AG, Kashirina DN, Goncharov IN, Larina IM.Influence of factors of 21-day head-down bedrest on the blood level of myocardial extensibility biomarker ST2.Hum Physiol. 2023 Dec 23;49(6):605-8.
18. Shpakov AV, Primachenko GK, Voronov AV, Sokolov NN, Voronova AA, Puchkova AAInfluence of 21-day antiorthostatic hypokinesia on the functional state of the musculoskeletal system of human.Hum Physiol. 2023 Dec 23;49(6):617-24.
19. Zelenskaya IS, Saveko AA, Amirova LE, Kitov VV, Nosikova IN, Zelenskii KA, Tomilovskaya ES.Grip force control in 21-day dry immersion.Hum Physiol. 2023 Dec 23;49(6):579-88.Note: From the abstract: “During space flight, the changes in the functions of the upper limbs can affect the quality of operator activity. At the same time, there are very few data on this topic, because most of the research is focused on the structure and functions of the lower extremities. The aim was to study the characteristics of the grip force control during the decrease of the support and proprioceptive sensory signals in the conditions of the ground-based model of the effects of space flight, Dry Immersion (DI).”