SPACELINE Current Awareness List

NASA Spaceline Current Awareness List #1,071 – 20 October 2023 (Space Life Science Research Results)

By Keith Cowing
Press Release
October 20, 2023
Filed under , , , , ,
NASA Spaceline Current Awareness List #1,071 – 20 October 2023 (Space Life Science Research Results)
Space Life Science Research Aboard The International Space Station

SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at Please send any correspondence to Shawna Byrd, SPACELINE Current Awareness Senior Editor, [email protected].

Call for articles to cite in the weekly lists: Authors at NASA Centers and NASA PIs—do you have an article that has recently published or will publish in the upcoming weeks within a peer-reviewed journal and is in the scope of space life sciences? If so, send it our way! Send your article to the email address mentioned above. Articles received by Wednesday will appear within that week’s list—articles received after Wednesday will appear the following week.

Papers deriving from NASA support:

Papers deriving from NASA support:

  1. Hasenstein KH, John SP, Vandenbrink JP.Assessing radish health during space cultivation by gene transcription.Plants (Basel). 2023 Sep 30;12(19):3458.PI: K.H. HasensteinNote: ISS results. This article is part of Topical Collection “Feature Papers in Plant Development and Morphogenesis” ( and may be obtained online without charge.

    Journal Impact Factor: 4.5

    Funding: “This research was partially supported by NASA grants NNX10AP91G and 80NSSC17K0344.”
  2. DeChurch LA, Lungeanu A, Contractor NS.Think like a team: Shared mental models predict creativity and problem-solving in space analogs.Acta Astronaut. 2023 Oct 13. Online ahead of print.PIs: L.A. DeChurch, N.S. ContractorNote: This article may be obtained online without charge.

    Journal Impact Factor: 3.5

    Funding: “This work was supported by the National Aeronautics and Space Administration under awards No. 80NSSC18K0221, 80NSSC18K0276, NNX15AM32G, and 80NSSC21K0925.”
  3. Goeres DM, Velez-Justiniano Y-A, Kjellerup BV, McLean RJC.Biofilm and human spaceflight.Biofilm. 2023 Aug 18;100150. Online ahead of print.PI: R.J.C. McLeanNote: This article is an editorial to the special issue titled Biofilm (

    Journal Impact Factor: 6.8

    Funding: “PI reports NASA grant #NNX17AC79G support. YAVJ received funding from NASA MSFC Exploration Capabilities Life Support Systems and NASA HQ Polaris Project Bioremediation of Microgravity Biofilms and Water Processor Health. RJCM received funding from NSF Grant 2224449 and NASA Grant HS5HWWK1AAU5. DMG received funding from NASA/Marshall Space Flight Center contract #80NSSC23PA885.”
  4. Zupanska AK, Arena C, Zuñiga GE, Casanova-Katny A, Turnbull JD, Bravo LA, Ramos P, Sun H, Shishov VV.Editorial: Revisiting the limits of plant life – plant adaptations to extreme terrestrial environments relating to astrobiology and space biology.Front Plant Sci. 2023 Aug 17;14:1267183.PI: A.K. ZupanskaNote: This is the editorial to Research Topic “Revisiting the Limits of Plant Life – Plant Adaptations to Extreme Terrestrial Environments Relating to Astrobiology and Space Biology” (—plant-adaptations-to-extreme-terrestrial-environments-relating-to-astrobiology-and-space-biology#overview). The Research Topic also includes an article from previous Current Awareness List #1,019 This article may be obtained online without charge.

    Journal Impact Factor: 5.6

    Funding: PI reports NASA grant #80NSSC22K0208 support.
  5. Bongrand C, Foster JS.Modeled microgravity impacts Vibrio fischeri population structure in a mutualistic association with an animal host.Environ Microbiol. 2023 Oct 12. Online ahead of print.PI: J.S. FosterNote: High aspect ratio vessels were used in this study.

    Journal Impact Factor: 5.1

    Funding: “80NSSC18K1465/NASA; 80NSSC19K0138/NASA”
  6. Hicks J, Olson M, Mitchell C, Juran CM, Paul AM.The impact of microgravity on immunological states.Immunohorizons. 2023 Oct 19;7(10):670-82.Note: This article may be obtained online without charge.

    Journal Impact Factor: 2.6

    Funding: C.M. Juran and A.M. Paul are affiliated with NASA Ames Research Center.
  7. Lam CW, Castranova V, Driscoll K, Warheit D, Ryder V, Zhang Y, Zeidler-Erdely P, Hunter R, Scully R, Wallace W, James J, Crucian B, Nelman M, McCluskey R, Gardner D, Renne R, McClellan R.A review of pulmonary neutrophilia and insights into the key role of neutrophils in particle-induced pathogenesis in the lung from animal studies of lunar dusts and other poorly soluble dust particles.Crit Rev Toxicol. 2023 Oct 18;1-39. Review. Online ahead of print.Journal Impact Factor: 5.9

    Funding: “The LD toxicity studies were funded by the NASA Human Research Program Grant through NASA’s JSC and Wyle Bioastronautics Contract #NAS9-02078. This project was funded by the NASA Human Research Program. Under the NASA-NIOSH government interagency arrangement/agreement, the NIOSH provided (without compensation) scientific staff and technological expertise to conduct the LD intratracheal instillation studies in rats, the participation of the principal investigator of the NASA LD studies, at the NIOSH facility. …”
  8. Pasetes LN, Rosendahl-Garcia KM, Goel N.Impact of bimonthly repeated total sleep deprivation and recovery sleep on cardiovascular indices.Physiol Rep. 2023 Oct 17;11(20):e15841.PI: N. GoelNote: This article may be obtained online without charge.

    Journal Impact Factor: 2.5

    Funding: “This research was funded by the National Aeronautics and Space Administration (NASA) [grant numbers NNX14AN49G and 80NSSC20K0243 (to N.G.)]. This work was also partially supported by the National Institutes of Health [grant number NIH R01DK117488 (to N.G.)].”
  9. Hearon CM Jr, Peters K, Dias KA, Macnamara JP, Marshall JET, Campain J, Martin D, Marshall-Goebel K, Levine BD.Assessment of venous pressure by compression sonography of the internal jugular vein during 3 days of bed rest.Exp Physiol. 2023 Oct 12. Online ahead of print.Note: Bedrest study. This article may be obtained online without charge.

    Journal Impact Factor: 2.7

    Funding: “This study was supported by NASA (grants 80NSSC19K0300 and 80NSSC19K0300-P00001) and the CTSA program grant from the National Center for Advancing Translational Sciences (5UL1TR001105).”
  10. Suh A, Ong J, Kamran SA, Waisberg E, Paladugu P, Zaman N, Sarker P, Tavakkoli A, Lee AG.Retina oculomics in neurodegenerative disease.Ann Biomed Eng. 2023 Oct 19. Review.PI: A. TavakkoliJournal Impact Factor: 3.8

    Funding: “NASA Grant [80NSSC20K183]: A Non-intrusive Ocular Monitoring Framework to Model Ocular Structure and Functional Changes due to Long-term Spaceflight.”

Other papers of interest:

  1. Yin YS, Zhu YB, Liu JL, Fan QC, Wu XR, Zhao S, Wang JP, Liu Y, Li YZ, Lu WH.Long-term spaceflight composite stress induces depressive behaviors in model rats through disrupting hippocampus synaptic plasticity.CNS Neurosci Ther. 2023 Oct 17. Online ahead of print.Note: From the introduction: “In this study, we used a combination of five factors to simulate the long-term spaceflight composite stress (LSCS) environment, including microgravity, isolation and con-finement, noise, circadian rhythm disruptions, and low pressure, which were much closer to the real space station environment than simply simulating a single factor.” This article may be obtained online without charge.
  2. Ax T, Ganse B, Fries FN, Szentmáry N, de Paiva CS, March de Ribot F, Jensen SO, Seitz B, Millar TJ.Dry eye disease in astronauts: A narrative review.Front Physiol. 2023 Oct 19;14:1281327. Mini review.Note: This article may be obtained online without charge.
  3. Xue F, Zhang L, Li L, Wang Z, Song D.A new composite control strategy for an astronaut virtual operation training system based on cable-driven technology.Actuators. 2023 Oct 12;12(10):384.Note: This article is part of Section “Actuators for Robotics” ( From the introduction: “In the weightless environment of space, the motion characteristics and mechanical properties of objects are very different from those in the Earth’s gravitational environment. An astronaut’s senses in the process of carrying objects and installing equipment are also different compared to the experience within the terrestrial gravitational environment. Due to the inability to feel gravity during the process of moving objects and disassembling and assembling equipment, the motion of objects can result in collision and damage to the equipment and even cause harm to the astronauts, such as tearing inflicted upon the spacesuit.” This article may be obtained online without charge.
  4. Renaud C, Leys N, Wattiez R.Photosynthetic microorganisms, an overview of their biostimulant effects on plants and perspectives for space agriculture.Journal of Plant Interactions. 2023 Dec 23;18(1):2242697. Review.Note: From the abstract: “In this review, we provide an overview of the current state of knowledge about existing biostimulants, their effects and applications, and the potential brought by photosynthetic microorganisms for life in closed environments.”
  5. Vrankar D, Verseux C, Heinicke C.An airlock concept to reduce contamination risks during the human exploration of Mars.npj Microgravity. 2023 Oct 7;9(1):81.Note: From the abstract: “With this paper, we attempt to reconcile these two conflicting goals: the human exploration of Mars and its protection from biological contamination.” This article may be obtained online without charge.
  6. Ge Y, Zhang B, Song J, Cao Q, Bu Y, Li P, Bai Y, Yang C, Xie M.Discovery of salidroside as a novel non-coding RNA modulator to delay cellular senescence and promote BK-dependent apoptosis in cerebrovascular smooth muscle cells of simulated microgravity rats.Int J Mol Sci. 2023 Sep 26;24(19):14531.Note: Hindlimb unloading study. This article is part of Topical Collection “Regulation by Non-Coding RNAs” ( and may be obtained online without charge.
  7. Kramer T, Hoenemann JN, Weis H, Hoffmann F, Rosenkranz S, Baldus S, Hellmich M, Levine BD, Jordan J, Tank J, Limper U.Electrocardiographic changes during sustained normobaric hypoxia in patients after myocardial infarction.Sci Rep. 2023 Oct 14;13:17452.Note: This article may be obtained online without charge.
  8. Xing C, Wang H, Zhu J, Zhang C, Li X.Impact of gravity on fluid flow and solute transport in the bone lacunar-canalicular system: A multiscale numerical simulation study.Comput Methods Biomech Biomed Engin. 2023 Oct 16;1-10. Online ahead of print.


Explorers Club Fellow, ex-NASA Space Station Payload manager/space biologist, Away Teams, Journalist, Lapsed climber, Synaesthete, Na’Vi-Jedi-Freman-Buddhist-mix, ASL, Devon Island and Everest Base Camp veteran, (he/him) 🖖🏻