NASA Spaceline Current Awareness List #1,165 8 September 2025 (Space Life Science Research Results)
The abstract in PubMed or at the publisher’s site is linked when available and will open in a new window.
Papers deriving from NASA support:
- Meer EA, Church LE, Johnson BA, Rohde J, Sinclair AJ, Mollan SP, Petersen L, Polk JD, Sawyer AJ.Non invasive monitoring for spaceflight associated neuro ocular syndrome: Responding to a need for in flight methodologies.npj Microgravity. 2025 Sep 1;11:61.Note: This article may be obtained online without charge.
Journal Impact Factor: 5.1
Funding: “For support of this work we would like to acknowledge the UCSF Department of Orthopaedic Surgery, the UC Space Health Program, and the Translational Research Institute of Space Health through NASA Cooperative Agreement NNX16AO69A.” - Gulacsi E, Sabou M, Olsen T.Simulated galactic cosmic rays effects on fungal materials: Towards biotechnological radiation protection for space habitats.Int J Radiat Biol. 2025 Sep 2;1-10. Online ahead of print.Note: From the abstract: “This paper will present the data of the heavy ion radiation experiment carried out at the NASA Space Radiation Laboratory (New York, US) with Aspergillus niger, Cladosporium sp. and Cryptococcus neoformans. Fungi present a promising avenue for increasing the safety of future space exploration.”
Journal Impact Factor: 2.4
Funding: “The authors wish to thank the staff at the Brookhaven National Laboratory and the NASA Space Radiation Laboratory for their invaluable help.” - Smith GR, Uysal-Onganer P, Kraev I, van Breukelen F, Lange S.Immune tuning in extreme environments: Protein citrullinome and extracellular vesicle signatures comparing hibernating versus active states in the heterothermic and heterometabolic tenrec (Tenrec ecaudatus).Biology. 2025 Aug 15;14(8):1056.Note: This article is part of Section “Immunology” (https://www.mdpi.com/journal/biology/sections/Immun) and may be obtained online without charge.
Journal Impact Factor: 3.5
Funding: “Funding was provided by the National Science Foundation grants IOB 0448396 and IOS 1655091, Quality-related (QR) funding from the University of Westminster and the NASA Translational Research Institute for Space Health Biomedical Research Advances for Space Health 2101 grant.” - Cassilly CD, Chander AM, Vaughn JA, Kunstman KJ, Green SJ, Venkateswaran K, Bertone PF, Bahr CW, Marcella SA, Morris HC.Effects of simulated space environmental conditions on cleanroom microbes.Front Microbiol. 2025 Aug 18;16:1600106.Note: This article is part of Research Topic “AI and Omics Approaches to Microbial Interactions: Applications for Space and Earth” (https://www.frontiersin.org/research-topics/62376/ai-and-omics-approaches-to-microbial-interactions-applications-for-space-and-earth). This article may be obtained online without charge.
Journal Impact Factor: 4.5
Funding: “The research described in this manuscript was partially funded by Amentum Space Exploration Division Technology Innovation and Process Improvement grants: C803-Molecular Identification of Microbial Contaminants and Innovation Lab Microbiology Equipment grant and C903-Space Environmental Effects on Clean Room Microbes grant to CDC. It was also partially funded by the NASA ROSES grant NNH18ZDA001N-PPR award 18-PPR18-0011 to KV.”
Other papers of interest:
Yu H, Mu Q, Liu C, Wang S, Sun J.Technical system of electroencephalography-based brain-computer interface: Advances, applications, and challenges.Neural Regen Res. 2025 Sep 3. Review. Online ahead of print.Note: This article may be obtained online without charge.
Lampert R, Goel R, Oblanca JV, Martins DF.From astronauts to stroke survivors: How the TheraSuit Method® can boost balance and recovery.Front Neurol. 2025 Aug 12;16:1581256.Note: This article is a Perspective and may be obtained online without charge
Le Roy B, Claverie D, Sauvadet L, Martin-Krumm C, Trousselard M.We have liftoff: A discovery study to use artificial intelligence to identify adaptative profiles for future space missions.Physiol Rep. 2025 Aug 29;13(17):e70447.Note: From the abstract: “Long-duration space missions will challenge astronauts’ adaptive capacities. Interoception and heart rate variability (HRV), reflecting parasympathetic activity, are increasingly recognized as predictors of adaptation and health. This study investigated whether artificial intelligence may predict adaptation profiles from interoceptive and HRV responses across different space analogs. Data were collected from 84 participants in four environments: parabolic flight, nuclear submarine, sea survival simulation, and chemical/biological hazard exercises.” This article may be obtained online without charge.
Ma X, Wang D, Wang Y, Wang F, Qu A.Pulmonary contusion risk assessment in astronauts during off-nominal Earth-return capsule landings.Ann Biomed Eng. 2025 Sep 4. Online ahead of print.
Jensen AB, Copplestone D, Guidetti R, Heer M, Pittia P, Berggren Å.Immune challenges and pathogen risks in edible insects: Safeguarding health in space life-support systems.Front Physiol. 2025 Sep 2;16:1628696. Review.Note: This article is part of Research Topic “Innovations in Tools and Methods for Life Sciences Research in Space” (https://www.frontiersin.org/research-topics/68978/innovations-in-tools-and-methods-for-life-sciences-research-in-space). The Research Topic also includes articles from previous Current Awareness Lists #1,155 https://doi.org/10.3389/fphys.2025.1599005 and #1,156 https://doi.org/10.3389/fphys.2025.1622401. This article may be obtained online without charge.
Chen F, Jiang N, Khan MN, Zhang Y, Shakir MZ, Zhou G, Xia C, Xu Y, Lv G, Xie M, Liu X.Protective effects of Compound Gastrodia elata formula on the cognitive impairment induced by simulated weightlessness in mice.Life Sci Space Res. 2025 Aug 31. Online ahead of print.Note: Hindlimb unloading study.
Amith M, Vu J, Hou S, Sista V, Gong Y, Shah R, Neumann AC.Rendering knowledge graphs from aerospace dentistry processes for clinical decision support systems.Acta Astronaut. 2025 Aug. 28. Online ahead of print.
Ray A, Parvez F, Islam M.A scoping review on microgravity medicine: Challenges and breakthroughs in space healthcare.Space Habitation. 2025 Sep;1(2):100017.
Zhou Z, Li S, Lv Y, Liu K, Cao Y, Guo S.A deep learning framework for multi-object tracking in space animal behavior studies.Animals (Basel). 2025 Aug 20;15(16):2448.Note: This article may be obtained online without charge.
Mannes Guesser De Oliveira S, Rezwan K, Verseux C, Maas M.3D printing of composites of Martian regolith simulants and cyanobacterial biomass towards sustainable material production on Mars.npj Microgravity. 2025 Aug 29;11:60.Note: This article may be obtained online without charge.
Jacob P, Robin A, Navasiolava N, Custaud MA, Ghislin S, Bareille MP, De Villemeur RB, Antunes I, Van Ombergen A, Gauquelin-Koch G, Frippiat JP.ESA VIVALDI dry immersion microgravity simulations induce increases in immune biomarkers associated with physical and psychological stress, and sex-specific factors.Faseb j. 2025 Sep 15;39(17):e70993.Note: This article may be obtained online without charge.
González-Torres LF, Grimm D, Krüger M.The effects of microgravity on the structure and function of cardiomyocytes.Biomolecules. 2025 Aug 30;15(9):1261.Note: This article is part of Special Issue “Effects of Weightlessness on Molecular Changes in Cellular Organisms, Animals and Plants: 2nd Edition” (https://www.mdpi.com/journal/biomolecules/special_issues/5T02P84N7Y) and may be obtained online without charge.
Silburn A.Counteracting microgravity: Preserving cardiovascular health in low Earth orbit.Mil Med Res. 2025 Sep 1;12:53.Note: This article is a Letter to the Editor and may be obtained online without charge.
Dubayle D, Morel J-L, Lemarchant S.Blood-spinal cord barrier alterations in a mouse model of centrifugation-induced hypergravity.Front Physiol. 2025 Sep 1;16:1658389.Note: This article may be obtained online without charge.
Grimm D.Effects of weightlessness on molecular changes in cellular organisms, animals, and plants.Biomolecules. 2025 Aug 21;15(8):1207.Note: This article is an Editorial and is part of Special Issue “Effects of Weightlessness on Molecular Changes in Cellular Organisms, Animals, and Plants” (https://www.mdpi.com/journal/biomolecules/special_issues/5JR4HV8X19). This article may be obtained online without charge.
Liao Y, Lu D, Yang J.Changes and monitoring technology of human heart rate and blood oxygen saturation under high-altitude hypoxia.Front Physiol. 2025 Aug 31;16:1642777.Note: This article is part of Research Topic “Physiological and Pathological Responses to Hypoxia and High Altitude, Volume III” (https://www.frontiersin.org/research-topics/66099/physiological-and-pathological-responses-to-hypoxia-and-high-altitude-volume-iii). The Research Topic also includes an article from previous Current Awareness List #1,159 https://doi.org/10.3389/fphys.2025.1617136. This article may be obtained online without charge.
Liang Y, Yuan Y, Cai Y, Ma M, Lin X, Sun X, Zhao H, Zhai J, Han N, Zhou J, Wang W, Wang Y, Zhang N.HSFA2D-LAZY6-LAZY1 module regulates shoot gravitropism and tiller angle in rice.New Phytologist. 2025 May 23;247(2):625-36.Note: This article may be obtained online without charge.
Yang J, Wang C, Fu D, Ho LL, Galani K, Chen L, Gonzalez J, Fu J, Huang AY, Frederick DT, He L, Asnani M, Tacke R, Robitschek EJ, Yadav SK, Deng W, Burke KP, Sharova T, Sullivan RJ, Weiss S, Rai K, Liu D, Boland GM, Kellis M.Mature and migratory dendritic cells promote immune infiltration and response to anti-PD-1 checkpoint blockade in metastatic melanoma.Nat Commun. 2025 Sep 1;16:8151.Note: This article may be obtained online without charge.
Astrobiology, space biology, space medicine, microgravity, space station,
