Sample Return

Mars Sample Return Campaign: Biological Risk And A Proposed Sample Safety Assessment Protocol

By Keith Cowing
Press Release
June 3, 2026
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Mars Sample Return Campaign: Biological Risk And A Proposed Sample Safety Assessment Protocol
Overview of the proposed sample safety assessment protocol summarizing the workflow and decision-making processes. Reprinted from reference 5, previously published — Applied and Industrial Microbiology

Returning surface samples from Mars to Earth has been a major planetary science objective, with the potential for the detection of microbiological life and the possibility of improving our understanding of the origins of life.

The National Aeronautics and Space Administration and the European Space Agency assembled a team to assess the level of risk that returned samples could contain potential biohazards.

The team was chartered with optimizing previous sample safety assessment strategies, defining what constitutes a biological hazard, developing a protocol to test for biohazards, and establishing a statistical framework to determine if samples may be safe for release from a high-containment facility.

This report presents the biological context for a proposed three-step protocol for testing returned samples, including how to determine if microorganisms are present, and if they could be (or were recently) alive.

Summary of the proposed Step 3 (biological activity). — Applied and Industrial Microbiology

Astrobiology,

Biologist, Explorers Club Fellow, ex-NASA Space Biologist and Payload integrator, Editor of NASAWatch.com and Astrobiology.com, Lapsed climber, Explorer, Synaesthete, Former Challenger Center board member 🖖🏻