NASA Spaceline Current Awareness List #1,121 25 October 2024 (Space Life Science Research Results)
The abstract in PubMed or at the publisher’s site is linked when available and will open in a new window.
Papers deriving from NASA support:
- Arnold C, Casaletto J, Heller P.Spaceflight disrupts gene expression of estrogen signaling in rodent mammary tissue.Med Res Arch. 2024 Sep 11;12(3).Note: ISS results. This article may be obtained online without charge.
Journal Impact Factor: Not available for this journal
Funding: J. Casaletto is affiliated with NASA Ames Research Center. - Kozbenko T, Adam N, Grybas VS, Smith BJ, Alomar D, Hocking R, Abdelaziz J, Pace A, Boerma M, Azimzadeh O, Blattnig S, Hamada N, Yauk C, Wilkins R, Chauhan V.AOP report: Development of an adverse outcome pathway for deposition of energy leading to abnormal vascular remodeling.Environ Mol Mutagen. 2024 Oct 23. Online ahead of print.Note: This article may be obtained online without charge.
Journal Impact Factor: 2.3
Funding: S. Blattnig is affiliated with NASA Langley Research Center. - Hong K, Zhang R, Lee KG, Young PR, Joiner WM, Robinson SK, Goncu-Berk G, Schofield SJ.A wearable haptic sleeve interface for spaceflight robotic arm operations.JACM. 2024 Oct 5;318-22.PI: S.K. RobinsonNote: This article is a meeting proceedings that published in peer-reviewed Journal of the ACM and may be obtained online without charge.
Journal Impact Factor: 2.3
Funding: “This material is based upon work supported by NASA’s Human Research Program – Grant Number 80NSSC21K1373.”
Other papers of interest:
- Marotta D, Ijaz L, Barbar L, Nijsure M, Stein J, Pirjanian N, Kruglikov I, Clements T, Stoudemire J, Grisanti P, Noggle SA, Loring JF, Fossati V.Effects of microgravity on human iPSC-derived neural organoids on the International Space Station.Stem Cells Transl Med. 2024 Oct 23. Online ahead of print.Note: ISS results. This article may be obtained online without charge.
- Tran QD, Spooner N, Geoghehan S, Thavarajah SR, Rahman S, Tran NN, Williams PM, Jarquin SM, Kim DH, Davey K, Buell J, Shumbera M, Gittleman M, Clements T, Stoudemire J, Fisk I, Hessel V.Cosmic-ray radiation effects on ibuprofen tablet formulation inside and outside of the International Space Station.Adv Healthc Mater. 2024 Oct 23:e2402361.Note: ISS results.
- Lazow SP, Siu M, Brown L, Kamine TH.Percutaneous cholecystostomy for acute cholecystitis during spaceflight.Aerosp Med Hum Perform. 2024 Oct;95(10):771-6. Review.Note: From the abstract: “Acute calculous cholecystitis is a common surgical emergency and cholecystectomy is the gold-standard treatment. However, alternative drainage modalities such as percutaneous cholecystostomy tube (PCT) placement have been proposed for poor surgical candidates or in remote environments, such as space. We reviewed the literature to assess the theoretical utility of PCT to treat acute cholecystitis during long-duration spaceflight or on the Moon or Mars.”
- Murali A, Sarkar RR.Dynamic cellular responses to gravitational forces: Exploring the impact on white blood cell(s).Biomicrofluidics. 2024 Oct 21;18(5):054112.
- Nie HY, Ge J, Huang GX, Liu KG, Yue Y, Li H, Lin HG, Zhang T, Yan HF, Xu BX, Sun HW, Yang JW, Si SY, Zhou JL, Cui Y.New insights into the intestinal barrier through “gut-organ” axes and a glimpse of the microgravity’s effects on intestinal barrier.Front Physiol. 2024 Oct 9;15:1465649. Review.Note: This article is part of Research Topic “Gastrointestinal Damage and Metabolic Disorders” (https://www.frontiersin.org/research-topics/61941/gastrointestinal-damage-and-metabolic-disorders/overview) and may be obtained online without charge.
- Qaisar R, Srinivas M, Gul MT, Khan AA, Ranade A, Jose J, Ramachandran G, Ebby S, Ahmad F, Karim A.Mesenchymal stem cell transplant as an intervention to ameliorate disuse-induced muscle atrophy in a mouse model of simulated microgravity.Acta Astronaut. 2024 Oct 24. Online ahead of print.Note: Hindlimb unloading study.
- Velarde M, Sempore MY, Allibert V, Montel V, Castells J, Treffel L, Chopard A, Brioche T, Cochon L, Morel J, Bastide B, Durieux AC, Stevens L, Freyssenet D.Molecular determinants of skeletal muscle force loss in response to 5 days of dry immersion in human.J Cachexia Sarcopenia Muscle. 2024 Oct 25. Online ahead of print.Note: This article may be obtained online without charge.
- Cheng L, Li Y, Yan J.Review insights into the field of space life sciences.Life Sci Space Res. 2024 Oct 21. Review. Online ahead of print.Note: From the abstract: From the abstract: “This review summarizes studies in various key topics in space life science, namely, how microbiome changes in humans and plants, the development of space agriculture and the use of animal, plant, and cell models to study the effect of space environments on physiology.”
- Doarn CR.Evolution of space medicine at NASA.Aerosp Med Hum Perform. 2024 Oct;95(10):797-805.Note: From abstract: “From the very beginning of America’s human spaceflight program, space medicine has been at the forefront. There has been a variety of diverse individuals, over six decades, whose contributions helped shape what space medicine is within NASA today.”
- Green DA.SpaceX must share astronaut health data to boost space biomedicine.Nature. 2024 Oct 22;634(8035):782.Note: This article is a correspondence.
- Geipel I.Beautiful new sky: Fabricating bodies for outer space in East Germany’s military.Cambridge, United Kingdom: Polity Press, 2024. 178 p.
- Greenberger J.Prolonged effects of physiological change, psycho-social stress, zero gravity, alterations in the intestinal microbiome, and metabolism on the response to space irradiation.In: Greenberger J, ed. Radiation Oncology and Radiation Biology: The Next 100 Years. Chaum, Switzerland: Springer, 2024. p. 93-103.
- Khune AV, M N, Markam S, Berad A.Physiological responses to space travel: A systematic review.E J Cardiovasc Med. 2024 Oct;14(5):450-4. Review.Note: From the abstract: “Space travel, particularly long-duration missions, poses unique physiological challenges due to microgravity, radiation exposure, confinement, and isolation. This systematic review aims to synthesize the current understanding of the physiological changes that occur in astronauts during space travel.”
- Wang J, Lei M, Xue Y, Tan Q, He X, Guan J, Song W, Ma H, Wu B, Cui X.Assessment of toxicity changes induced by exposure of human cells to lunar dust simulant.Sci Rep. 2024 Oct 21;14:24781.Note: This article may be obtained online without charge.
- Suwanprakorn N, Shin K-J, Tran PH, Truong NT, Kim K-S, Yoo HJ, Yang S-G.Transcriptomic analysis of embryonic mouse hypothalamic N38 cells exposed to high-energy protons and/or simulated microgravity.Heliyon. 2024 Oct 30;10(20):e39533.Note: From the abstract: “Space exploration poses unique challenges to astronauts, especially the effects of space radiation and microgravity (μG). Understanding molecular responses to these factors is crucial for ensuring astronaut health, and this study aimed to identify transcriptomic changes in mouse hypothalamic cell line N38 (mHypoE-N38) caused by simulated space environments.” This article may be obtained online without charge.
- Leinonen AM, Varis NO, Kokki HJ, Leino TK.Normobaric hypoxia symptom recognition in three training sessions.Aerosp Med Hum Perform. 2024 Oct;95(10):758-64
- Amly W, Chen C-Y, Isa T.Modeling saccade reaction time in marmosets: The contribution of earlier visual response and variable inhibition.Front Syst Neurosci. 2024 Oct 23;18:1478019.Note: From the abstract: “Marmosets are expected to serve as a valuable model for studying the primate visuomotor system due to their similar oculomotor behaviors to humans and macaques. Despite these similarities, differences exist; challenges in training marmosets on tasks requiring suppression of unwanted saccades, having consistently shorter, yet more variable saccade reaction times (SRT) compared to humans and macaques. This study investigates whether the short and variable SRT in marmosets is related to differences in visual signal transduction and variability in inhibitory control.” This article may be obtained online without charge.
- Gatterer H, Dünnwald T, Woyke S, Faulhaber M, Schumacher YO, Schobersberger W.Low-dose carbon monoxide inhalation to increase total hemoglobin mass and endurance performance: Scientific evidence and implications.Front Physiol. 2024 Oct 15;15:1490205.Note: From the abstract: “Recently, chronic intermittent inhalation of low-dose carbon monoxide (CO) has been postulated as a practice to increase total hemoglobin mass with potential beneficial effects on endurance performance. In this perspective article, we discuss the potential performance enhancing capabilities as well as the safety concerns, which include individual variability in CO response, and acute and chronic health effects.” This article may be obtained online without charge.
- Tomzig M, Wörle J, Gary S, Baumann M, Neukum A.Strategic naps in automated driving – Sleep architecture predicts sleep inertia better than nap duration.Accid Anal Prev. 2024 Oct 19;209:107811.
- Roginski MA, Atchinson PRA, Esteves AM, Lentz SA, Fjeld KJ, Markwood JM, Lauria MJ, Bernardoni B.Acute respiratory distress syndrome: Updates for critical care transport.Air Medical Journal. 2024 Oct 9. Online ahead of print.Note: From the abstract: “Acute respiratory distress syndrome (ARDS) is characterized by acute diffuse lung injury resulting in bilateral pulmonary infiltrates and hypoxemia. This pathophysiology requires tailored management including treatment of the underlying cause, lung protective mechanical ventilation, prone positioning, selective use of extracorporeal membrane oxygenation, and adjunctive therapies. The objective of this narrative review is an evidence-based update on ARDS management in the critical care transport setting.”
- Linhardt RM, Berger L, Salas E.No laughing matter: How autonomous agents can improve well-being and teamwork.Acta Astronaut. 2024 Oct 18. Online ahead of print.
astrobiology, space biology, space medicine, microgravity,