NASA Spaceline Current Awareness List #1,069 6 October 2023 (Space Life Science Research Results)

Papers deriving from NASA support:

1. Alwood JS, Mulavara AP, Iyer J, Mhatre SD, Rosi S, Shelhamer M, Davis C, Jones CW, Mao XW, Desai RI, Whitmire AM, Williams TJ.Circuits and biomarkers of the central nervous system relating to astronaut performance: Summary report for a NASA-sponsored technical interchange meeting.Life (Basel). 2023 Aug 31;13(9)1852.Note: This article is a perspective and is part of Special Issue “Current Challenges in Space Neuroscience” (https://www.mdpi.com/journal/life/special_issues/XR00G704U3). The Special Issue also includes an article from previous Current Awareness List #1,042 https://doi.org/10.3390/life13030826, #1,046 https://doi.org/10.3390/life13041002, #1,052 https://doi.org/10.3390/life13051214, #1,053 https://doi.org/10.3390/life13061293, and #1,065 https://genelab.nasa.gov. Additional articles will be forthcoming and may be found in the link to the Special Issue. This article may be obtained online without charge.
   
   Journal Impact Factor: 3.2
   
   Funding: “This technical interchange meeting was funded by NASA Human Research Program, through the Human Factors and Behavioral Performance Element in conjunction with Space Radiation Element and the Human Health Countermeasures Element.”
2. Masalkhi M, Ong J, Waisberg E, Berdahl J, Lee AG.Intraocular pressure during spaceflight and risk of glaucomatous damage in prolonged microgravity.Encyclopedia. 2023;3(4):1187-96.PI: J. BerdahlNote: This article is an entry in collection “Encyclopedia of Glaucoma” (https://www.mdpi.com/journal/encyclopedia/topical_collections/encyclopedia_glaucoma) and may be obtained online without charge.
   
   Journal Impact Factor: Not available for this publication
   
   Funding: PI reports funding from NASA grant number NCC 9-58-SMST00012.
3. Trappe T, Tesch P, Alkner B, Trappe S.Microgravity-induced skeletal muscle atrophy in women and men: Implications for long-duration spaceflights to the Moon and Mars.J Appl Physiol (1985). 2023 Oct 5. Online ahead of print.PI: S. TrappeNote: Head-down tilt bedrest study.
   
   Journal Impact Factor: 3.3
   
   Funding: “NNJ04HF72G/National Aeronautics and Space Administration (NASA); Swedish National Space Agency (SNSA).”
4. Cahoon DS, Rabin BM, Fisher DR, Shukitt-Hale B.Effects of HZE-particle exposure location and energy on brain inflammation and oxidative stress in ratsRadiat Res. 2023 Sep 27. Online ahead of print.PI: B.M. RabinJournal Impact Factor: 3.4
   
   Funding: “This research was support by NASA Grants NNX16AE06G and NNJ16HP45I.”
5. Cannon AE, Vanegas DC, Sabharwal T, Salmi ML, Wang J, Clark G, McLamore ES, Roux SJ.Polarized distribution of extracellular nucleotides promotes gravity-directed polarization of development in spores of Ceratopteris richardii.Front Plant Sci. 2023 Oct 3;14:1265458.PI: S.J. RouxNote: This article is part of Research Topic “Progressing the Future of Space Agriculture” (https://www.frontiersin.org/research-topics/52433/progressing-the-future-of-space-agriculture#overview). The Research Topic also includes an article from previous Current Awareness List #1,055 https://doi.org/10.3389/fpls.2023.1194753. This article may be obtained online without charge.
   
   Journal Impact Factor: 5.6
   
   Funding: “The authors declare financial support was received for the research, authorship, and/or publication of this article. This work was supported by grants from the National Aeronautics and Space Administration to SR, GC and MS (NNX13AM54G and NNX15AB85A), and the Florida Space Grant to EM (00091356).”
6. Chaudhari A, Wang X, Wu A, Liu H.Repeated transcranial photobiomodulation with light-emitting diodes improves psychomotor vigilance and EEG networks of the human brain.Bioengineering. 2023 Sep 5;10(9):1043.Note: This article is part of Topic “Machine Learning and Biomedical Sensors” (https://www.mdpi.com/topics/ML_biosens). This article may be obtained online without charge.
   
   Journal Impact Factor: 4.6
   
   Funding: “This research was funded in part by the Translational Research Institute for Space Health (TRISH), which was sponsored by National Aeronautics and Space Administration (NNX16AO69A).”
7. Grant LK, Gooley JJ, St Hilaire MA, Joffe H, Brainard GC, Van Reen E, Rüger M, Rajaratnam SMW, Lockley SW, Czeisler CA, Rahman SA.A pilot study of light exposure as a countermeasure for menstrual phase-dependent neurobehavioral performance impairment in women.Sleep Health. 2023 Sep 23. Online ahead of print.PIs: G.C. Brainard, S.W. Lockley, C.A. CzeislerJournal Impact Factor: 4.1
   
   Funding: “…G.C.B., C.A.C., and S.W.L. were supported in part by the National Space Biomedical Research Institute through NASA NCC 9-58; G.C.B. was supported, in part, by the Nova Institute. The project was supported by the National Center for Research Resources through grants to Brigham and Women’s Hospital General Clinical Research Center (NCRR M01 RR02635) and the Harvard Clinical and Translational Science Center (NCRR UL1 RR025758).”
8. Rahimzadeh V, Fogarty J, Caulfield T, Auñón-Chancellor S, Borry P, Candia J, Cohen IG, Covington M, Fernandez Lynch H, Greely HT, Hanlon M, Hatt J, Low L, Menikoff J, Meslin EM, Platts S, Ravitsky V, Ruttley T, Seidler RD, Sugarman J, Urquieta E, Williams MA, Wolpe PR, Donoviel D, McGuire AL.Ethically cleared to launch?Science. 2023 Sep;381(6665):1408-11.PI: M.A. WilliamsJournal Impact Factor: 56.9
   
   Funding: “This work is supported by the Translational Research Institute for Space Health through NASA Cooperative Agreement NNX16AO69A.”

Other papers of interest:

1. Kharchenko V, Golubkina N, Skrypnik L, Murariu OC, Vecchietti L, Caruso G.The effect of one-year seed spaceflight storage on yield, biochemical and mineral characteristics of mature leafy vegetables belonging to Brassicaceae, Apiaceae, and Asteraceae families.Horticulturae. 2023 Sep 25;9(10):1073.Note: ISS results. This article is part of Special Issue “Advanced Studies in Abiotic Stress Response Mechanism of Horticultural Plants” (https://www.mdpi.com/journal/horticulturae/special_issues/9RXKR6AN5U). Additional articles will be forthcoming and may be found in the link to the Special Issue. This article may be obtained online without charge.
2. Ghani F, Cheung I, Phillips A, Tawhai M, Ashworth E.Lung volume, capacity, and shape in microgravity: A systematic review and meta-analysis.Acta Astronaut. 2023 Nov;212:424-35. Review.
3. Handwerk L, Schreier HK, Kraft D, Shreder K, Hemmersbach R, Hauslage J, Bonig H, Wiesmüller L, Fournier C, Rall-Scharpf M.Simulating space conditions evokes different DNA damage responses in immature and mature cells of the human hematopoietic system.Int J Mol Sci. 2023 Sep 6;24(18):13761.Note: A 2D clinostat was used in this study. This article is part of Special Issue “DNA Replication and DNA Damage Response in Aging and Disease” (https://www.mdpi.com/journal/ijms/special_issues/DNA_ReplicationRepairDamage) and may be obtained online without charge.
4. Hu Y, Tian H, Chen W, Liu Y, Cao Y, Pei H, Ming C, Shan C, Chen X, Dai Z, Yang S, Shao Z, Lan S, Liu Y, Tong W.The critical role of the Piezo1/β-catenin/ATF4 axis on the stemness of Gli1⁺ BMSCs during simulated microgravity-induced bone loss.Adv Sci (Weinh). 2023 Sep 27;e2303375. Online ahead of print.Note: Hindlimb unloading study. This article may be obtained online without charge.
5. Li J, Xue C, Yang H, Zhang J, Li G, Li J, Kuang F, Chen J, Zhang S, Gao F, Kou Z, Zhang X, Dong L.Simulated weightlessness induces hippocampal insulin resistance and cognitive impairment.Life Sci. 2023 Sep 25;122112. Online ahead of print.Note: Hindlimb unloading study.
6. Maillard T.Hypogravity modeling of upper extremities: An investigation of manual handling in the workplace.Front Physiol. 2023 Oct 2;14:1198162.Note: This article is part of Research Topic “Women in Space Physiology 2022” (https://www.frontiersin.org/research-topics/34966/women-in-space-physiology-2022#overview). The Research Topic also includes articles from previous Current Awareness Lists #1,021 https://doi.org/10.3389/fphys.2022.1039924, #1,038 https://doi.org/10.3389/fphys.2023.1085545, #1,047 https://doi.org/10.3389/fphys.2023.1178077, and #1,049 https://doi.org/10.3389/fphys.2023.1162355. This article may be obtained online without charge.
7. Markina E, Tyrina E, Ratushnyy A, Andreeva E, Buravkova L.Heterotypic cell culture from mouse bone marrow under simulated microgravity: Lessons for stromal lineage functions.Int J Mol Sci. 2023 Sep 6;24(18):13746.Note: This article is part of Special Issue “New Insights into the Use of Mouse Models for the Study of Musculoskeletal Diseases” (https://www.mdpi.com/journal/ijms/special_issues/5J5X21E2KW). The Special Issue also includes an article from previous Current Awareness List #1,050 https://doi.org/10.3390/ijms24108594. This article may be obtained online without charge.
8. Muñoz-Hisado V, Ruiz-Blas F, Sobrado JM, Garcia-Lopez E, Martinez-Alonso E, Alcázar A, Cid C.Bacterial molecular machinery in the Martian cryosphere conditions.Front Microbiol. 2023 Jul 26;14:1176582.Note: This article is part of Research Topic “The Impact of the Space Environment on Microbial Growth and Behavior” (https://www.frontiersin.org/research-topics/27130/the-impact-of-the-space-environment-on-microbial-growth-and-behavior#overview). The Research Topic also includes articles from previous Current Awareness Lists #1,009 https://doi.org/10.3389/fmicb.2022.877625, https://doi.org/10.3389/fmicb.2022.893071, and https://doi.org/10.3389/fmicb.2022.909997; #1,041 https://doi.org/10.3389/fmicb.2023.1090740; #1,046 https://doi.org/10.3389/fmicb.2023.1155726; and #1,050 https://doi.org/10.3389/fmicb.2023.1150224. This article may be obtained online without charge.
9. Rappaport MB, Corbally CJ.Toward an etiology of spaceflight neuroplastic Syndrome: Evolutionary science leads to new hypotheses and program priorities.NeuroSci. 2023 Sep 25;4(4):247-62.Note: This article is a hypothesis and may be obtained online without charge.